Results 81 to 90 of about 50,612 (311)

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Organization of liver transplantation service in the Republic of Belarus

Трансплантология (Москва), 2018
The paper shows the main stages of introduction and organization of liver transplantation in the Republic of Belarus, the procedure of examination of patients on the waiting list for liver transplantation, and the experience of the first 37 orthotopic ...
O. O. Rummo, A. M. Dzyadzko, A. M. Fedoruk, A. E. Shcherba, A. F. Minov   +4 more
doaj   +1 more source

CD3ɛ Nanobody‐Engineered Extracellular Vesicles Driving In Vivo Generation of BiTE‐Secreting CAR‐Ts for Solid Tumor Therapy With Memory Response and Minimal Immunogenicity

Advanced Science, EarlyView.
HEK‐293T‐derived CD3ε Nb‐engineered EVs to generate dual‐targeting CAR‐T cells directly in vivo. These EVs selectively deliver CAR.BiTE transgenes into T cells and reprogramed to HLA‐G/PD‐L1‐targeting effector cells with enhanced memory and persistence.
Shi‐Wei Huang, Yu‐Chuan Lin, Chih‐Ming Pan, Yeh Chen, Ming‐You Shie, Cheng‐Yu Chen, Kai‐Wen Kan, Yi‐Wen Chen, Ming‐Chao Liu, Chung‐Chun Wu, Yu‐Ting Chiang, Huai‐Ping Ho, Chen‐Yu Lin, Pei‐Ying Lin, Yu‐Han Huang, Steffany Rusli, Wan‐Yu Mao, Pei‐Wen Huang, Sin‐Ting Wang, Wan‐Chen Tsai, Ya‐Hsu Chiu, Ting‐Hsun Lin, Wan‐Ling Chiang, Che‐Kai Chang, Zi‐Lun Lai, Mei‐Chih Chen, Shao‐Chih Chiu, Der‐Yang Cho   +27 more
wiley   +1 more source

The problem of hyperammoniemia after orthotopic liver transplantation

Трансплантология (Москва)
Background. Currently, there is no doubt that orthotopic liver transplantation increases life expectancy compared to standard treatment methods in patients with decompensated liver cirrhosis.
S. V. Zhuravel, P. Yu. Falevko, V. A. Manukovskiy, M. E. Malyshev   +3 more
doaj   +1 more source

Use of Mammalian Liver Cells for Artificial Liver Support

Cell Transplantation, 1996
Advances in orthotopic liver transplantation have improved the survival rate of both acute and chronic liver failure patients to nearly 70%. However, the success of this treatment modality has created an international organ shortage.
Hugo O. Jauregui M.D., Ph.D., Namita Roy Chowdhury, Jayanta Roy Chowdhury   +2 more
doaj   +1 more source

Clinical Characteristics and Risk Factors for Intra-Abdominal Infection with Chryseobacterium indologenes after Orthotopic Liver Transplantation [PDF]

, 2022
Yixin Zhang, Xiaoyu Zhao, Xu Su, Ying Li
openalex   +1 more source

Two‐stage portal flow modulation for volume‐augmented grafts in living donor liver transplantation: Rat model validation

Animal Models and Experimental Medicine, EarlyView.
This study presents a two‐stage portal flow modulation strategy for graft procurement in living donor liver transplantation with the aim of expanding left lateral lobe grafts, thereby circumventing technical and anatomical limitations of conventional approaches.
Yuqi Gong, Yutong Chen, Zhoucheng Wang, Libin Dong, Zhengxing Lian, Kai Wang, Xiao Xu   +6 more
wiley   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Acute Appendicitis after Liver Transplantation: A Case Report and Review of the Literature

International Journal of Organ Transplantation Medicine, 2017
Acute appendicitis is one of the most common etiologies for acute abdomen. However, fewer than 30 cases of acute appendicitis after liver transplantation have so far been reported in the literature.
SE Sheppard, HL Marecki, CM Psoinos, B Movahedi, MJ Furman, A Bozorgzadeh, PN Martins   +6 more
doaj  

Hyperbilirubinemia: Does It Matter?

Canadian Journal of Gastroenterology, 1999
Serum bilirubin concentrations are increased in several hematological and hepatic disorders; however, hyperbilirubinemia, often of familial origin, may occur without overt signs of hemolysis or evident liver disease.
Lajos Okolicsanyi, Giulia Martina Cavestro, Claudia Guatti-Zuliani   +2 more
doaj   +1 more source