Results 41 to 50 of about 2,096,772 (60)

Aryl Hydrocarbon Receptor in Health and Disease

MedComm, Volume 6, Issue 11, November 2025.
Based on the structure and ligands of AhR, this review introduces the AhR‐related signaling pathways and their roles in health and diseases. Agonists and antagonists of AhR as well as new strategies for treatment using the microbial–AhR axis are summarized. A prospect was made for the future use of AhR as a therapeutic target.
Haonan Li, Yufeng Fan, Jizheng Liu, Shumin Dong, Bin Wen, Yunfei Zhang, Xiaocui Wang, Xuemei Duan, Ying Hu, Ze Yan, Huifeng Shang, Yukai Jing   +11 more
wiley   +1 more source

Pan‐cancer analysis and oncogenic implications of MGAM and MGAM2: Toward precision oncology and drug repurposing in colorectal cancer

Journal of Cell Communication and Signaling, Volume 19, Issue 3, September 2025.
Abstract Cancer remains a major global health challenge, with high prevalence and mortality rates emphasizing the urgent need for innovative treatment strategies. Although precision oncology offers tailored therapies based on genetic profiles, the clinical translation of genomic insights has been slow.
Rawaa Chasib Mezher, Hanieh Azari, Reza Khayami, Hamid Fiuji, Farzaneh Alizadeh, Ladan Goshayeshi, Majid Rajabian, Ibrahim Saeed Gataa, Seyed Mahdi Hassanian, Amir Avan   +9 more
wiley   +1 more source

Research progress on traditional Chinese medicine animal models of post‐stroke depression and pathological insights

Animal Models and Experimental Medicine, Volume 8, Issue 8, Page 1387-1399, August 2025.
Post‐stroke depression (PSD) animal model of traditional Chinese medicine (TCM) combined with disease and syndrome often uses western medicine surgery (including: middle cerebral artery embolization to construct cerebral ischemia, or brain injection of collagenase to construct cerebral hemorrhage) combined with other methods (including: isolation ...
Jielin Wang, Wenlu Ma, Wei Wu, Yujuan Fu, Hui Li   +4 more
wiley   +1 more source

Film beyond boundaries: film, migrant narratives and other media Film beyond boundaries: film, migrant narratives and other media

Ilha do Desterro, 2008
The articles here presented are representative of the debates about the various transformational aspects of film studies, fostering the discussion about the transformations and interactions between national and international narrative forms, the ...
Anelise Reich Corseuil
doaj  

Study the past if you would define the future: Historical methods in medical education scholarship

Medical Education, Volume 59, Issue 8, Page 823-832, August 2025.
Abstract Introduction A study was conducted to describe the state of historical scholarship in medical education including its strengths and opportunities as well as its shortcomings, lacunae, inattentions, and failings. The study took a particular focus on historical methods and methodologies and whether they have been applied appropriately and with ...
Rachel Ellaway, Anna MacLeod, Susan van Schalkwyk, Jennifer Cleland   +3 more
wiley   +1 more source

Mechanism Analysis of Zuogui and Yougui Pills on Diabetic Nephropathy Through Transcriptional Regulatory Networks of HIF1A and PPARA

Food Science &Nutrition, Volume 13, Issue 6, June 2025.
The shared mechanisms of Zuogui Pill (ZGP) and Yougui Pill (YGP) for treating diabetic nephropathy is HIF1A‐CA9‐PDK1 and PPARA‐PDK4. ZGP and YGP inhibited renal fibrosis and relieved the decrease in glucose consumption through transcriptional regulatory network of HIF1A and PPARA.
Liansheng Qiao, Xiaopeng Zhao, Anlei Yuan, Chaoqun Liu, Zewen Wang, Xiaoqian Huo, Shijie Bi, Jiaye Tian, Bin Yu, Zhaozhou Lin, Yanling Zhang, Jiwang Zhang   +11 more
wiley   +1 more source

Machine Learning‐Enabled Drug‐Induced Toxicity Prediction

Advanced Science, Volume 12, Issue 16, April 24, 2025.
Unexpected toxicity accounts for 30% of drug development failures. This review highlights ML innovations in predicting drug‐induced toxicity, emphasizing comparative analyses, interpretable algorithms, and multi‐source data integration. It categorizes toxicity types, summarizes ML models, and organizes key databases, offering strategies to address ...
Changsen Bai, Lianlian Wu, Ruijiang Li, Yang Cao, Song He, Xiaochen Bo   +5 more
wiley   +1 more source

Serum Vitamin D Levels and Risk of Iron Deficiency Anemia in Adults: A Cross‐Sectional Study and Mendelian Randomization Analysis

Food Science &Nutrition, Volume 13, Issue 3, March 2025.
The results of our cross‐sectional analysis demonstrated a negative correlation between serum vitamin D levels and IDA. A non‐linear relationship between the two was found. ABSTRACT This study focuses on the potential role of vitamin D in the diagnosis and treatment of iron deficiency anemia (IDA), and evaluates causation using Mendelian randomization (
Leifei Chen, Nanyuan Gu, Kai Qiu, Hui Chen, Fu Tian, Yang Chen, Longhuan Zeng   +6 more
wiley   +1 more source

VALENTE, Rubens. Os fuzis e as flechas: história de sangue e resistência indígena na ditadura. 1 ed. São Paulo: Cia das Letras, 2017.

, 2022
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openaire   +1 more source

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A ARTE E A FORMAÇÃO DE PROFESSORES: UMA ANÁLISE DO FILME “OS FUZIS” DE RUY GUERRA COMO CAMINHO À COMPREENSÃO DA REALIDADE BRASILEIRA

ARACÊ
Diferentes abordagens pedagógicas têm se debruçado em levantar possibilidades que o diálogo com a arte proporciona para a formação intelectual e no processo de humanização dos sujeitos. Este artigo analisa a obra “Os Fuzis” (1964), de Ruy Guerra, focando nas relações entre cinema e educação, particularmente na formação inicial e continuada de ...
Tiago Serpa Barbosa Chaves, Marco Túlio Jorge Cortez, Laise Vieira Gonçalves, Antonio Fernandes Nascimento Junior   +3 more
openaire   +2 more sources