Results 181 to 190 of about 209,496 (210)

Diacerein Disrupts Testicular Homeostasis: The Essential Role of Basal Cytokines in Maintaining Sertoli Cell Integrity and the Immune Microenvironment

open access: yesAndrology, EarlyView.
ABSTRACT Background Pro‐inflammatory cytokines, TNF and IL‐1B, are essential for testicular homeostasis. Diacerein, an anti‐inflammatory drug, inhibits these cytokines, impairing M2 macrophages and Leydig cells (LCs). However, its impact on Sertoli cells (SCs) and M1 (CD68) macrophages remains unknown.
Elide Loise Freitas de Jesus   +6 more
wiley   +1 more source

Sleep Disorders in Klinefelter Syndrome and Other Sex Chromosome Aneuploidies: A Narrative Review

open access: yesAndrology, EarlyView.
ABSTRACT Background Sex chromosome aneuploidies (SCAs) are among the most frequent types of chromosomal aneuploidies and include Klinefelter syndrome (47,XXY and higher‐grade variants), 47,XYY syndrome, Turner syndrome (45,X), and trisomy X (47,XXX).
Roberto Paparella   +3 more
wiley   +1 more source

Dermal chondrosarcoma in a cat with prolonged survival after limb amputation

open access: yesAustralian Veterinary Journal, EarlyView.
A 5‐year‐old male entire domestic shorthair cat presented with a firm dermal mass on the dorsal left metatarsal region. Diagnostic investigations included haematology, biochemistry, urinalysis, biopsy, histopathology and computed tomography staging. Histopathology of the tissue biopsy, including immunohistochemistry, confirmed a dermal chondrosarcoma ...
A Ivanovs   +5 more
wiley   +1 more source

Sleep health of adults with cerebral palsy: A systematic review

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Although many people with cerebral palsy (CP) are adults, most sleep research in CP focuses on children. As poor sleep can affect pain, mood, energy, daily functioning, and quality of life we reviewed what is currently known about the sleep health of adults with CP. We searched three major research databases (MEDLINE, Embase, and CINAHL) up to February
Deepika Nagabhushan   +7 more
wiley   +1 more source

Weight Regain After Incretin Treatment: The Lean Mass Deficit Hypothesis and a Role for Testosterone Combination Therapy in Men

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs), dual glucose‐dependent insulinotropic polypeptide (GIP)/GLP‐1RA and triple (GIP)/GLP‐1RA/glucagon agonists achieve placebo‐subtracted weight loss of 15% to 22%. Their long‐term value depends on how well the weight loss is maintained and on the composition of weight loss, not only
Michael Zitzmann   +3 more
wiley   +1 more source

Sleep Medicine Education in Italian Undergraduate and Post‐Graduate Dental Programs

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Introduction Sleep‐related breathing disorders (SRBD), particularly obstructive sleep apnea (OSA), represent a major public health concern, yet remain widely underdiagnosed. Dentists play an important role in screening, referral, and management of SRBD; however, the extent of sleep medicine education in Italian dental curricula is unknown ...
Federica Guglielmi   +5 more
wiley   +1 more source

Current State of Moderate Congenital Haemophilia A and the Need for Preventive Treatment

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction The severity of haemophilia A is classified by the degree of factor VIII (FVIII) deficiency, rather than by clinical manifestations. However, FVIII activity alone does not necessarily accurately reflect clinical severity such as bleeding tendency, and patients with mild‐to‐moderate haemophilia A can experience significant disease ...
Masahiro Takeyama   +6 more
wiley   +1 more source

Orofacial pain disorder or trigeminal autonomic cephalalgia? Insights into pathophysiology and implications in medicine and dentistry

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
There are some headache disorders known as trigeminal autonomic cephalalgias (TACs). When these “headaches” are localized in the mid‐face region, they are known as “trigeminal autonomic orofacial pains” (TAOPs), and they can mimic other types of face pains including dental pain, which puts the patient at risk of receiving treatments that are incorrect.
Marcela Romero‐Reyes, Simon Akerman
wiley   +1 more source

Enhancing scar appearance: Results from a cosmetic clinical study on dexpanthenol‐containing silicone gel and massage ball in adults and children

open access: yesInternational Journal of Cosmetic Science, EarlyView.
This cosmetic clinical study demonstrates improvements in scar appearance associated with the use of a dexpanthenol‐containing silicone gel with an integrated massage ball in adults and children. Abstract Objective To evaluate changes in scar appearance and tolerability associated with 8 weeks of use of a test product comprising a topical dexpanthenol ...
Erwan Peltier   +3 more
wiley   +1 more source

Impact of a Case‐Based Sleep Apnoea Education on the Knowledge, Attitudes and Confidence of Dental Hygiene Students—A Multicentre Intervention Study

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Objective This pilot study aimed to explore knowledge, attitudes and confidence levels of Obstructive Sleep Apnoea (OSA) before and after case‐based education among dental hygiene students. Moreover, to give an international perspective, this study included students from the US and Scandinavia. Methods A longitudinal multicentre study assessed
Ann‐Catrin André Kramer   +6 more
wiley   +1 more source

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