Results 151 to 160 of about 15,651 (253)

Managed decline: Muddling through with the Sterling (dis)Agreements, 1968–74

open access: yesThe Economic History Review, EarlyView.
Abstract How do policymakers manage the decline of an international currency? This paper revisits the view that the ‘Sterling Agreements’ of 1968–74 – bilateral contracts between the UK and sterling‐holding governments – marked a successful paradigm shift towards sterling's managed ‘retirement’.
Alan de Bromhead   +3 more
wiley   +1 more source

Authors' Reply to Letter to the Editor: Sequential Ramucirumab Plus Docetaxel After PD‐1 Inhibitors

open access: yes
Cancer Science, EarlyView.
Kinnosuke Matsumoto   +2 more
wiley   +1 more source

Final Analysis of the Phase 1/2 Trial of Valoctocogene Roxaparvovec for Severe Haemophilia A

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Valoctocogene roxaparvovec is an adeno‐associated virus vector serotype 5 (AAV5)‐mediated gene therapy for severe haemophilia A (HA). Aim Report the final safety and efficacy results of the phase 1/2 trial of valoctocogene roxaparvovec. Methods An open‐label phase 1/2 trial (NCT02576795) enrolled adult males with severe HA (factor
Priyanka Raheja   +9 more
wiley   +1 more source

Real‐World Use of Emicizumab in Patients With Acquired Haemophilia A: An Interim Safety Analysis of a Large‐Scale Post‑Marketing Surveillance Study

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Acquired haemophilia A (AHA) is a rare autoimmune disorder where the development of autoantibodies to factor (F)VIII neutralise its function, leading to bleeding. Emicizumab has been approved for treating AHA in Japan. Aim This post‐marketing study was performed to primarily examine the use and safety of emicizumab, and indirectly
Midori Shima   +8 more
wiley   +1 more source

Beyond Standard Half‐Life: Real‐world Pharmacokinetics of Efanesoctocog Alfa in a Single Centre

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Efanesoctocog alfa (EFA) is an ultra–extended half‐life factor VIII (FVIII) developed to address limitations of conventional prophylaxis in haemophilia A. Although the XTEND trials reported low interindividual pharmacokinetic (PK) variability, real‐world data remain important to better characterize PK profiles across patient ...
Laurent Sattler   +6 more
wiley   +1 more source

Impact of obstructive sleep apnea on gut microbiome of patients with symptomatic intracranial atherosclerotic stenosis. [PDF]

open access: yesFront Aging Neurosci
Liao S   +11 more
europepmc   +1 more source

Enhancing scar appearance: Results from a cosmetic clinical study on dexpanthenol‐containing silicone gel and massage ball in adults and children

open access: yesInternational Journal of Cosmetic Science, EarlyView.
This cosmetic clinical study demonstrates improvements in scar appearance associated with the use of a dexpanthenol‐containing silicone gel with an integrated massage ball in adults and children. Abstract Objective To evaluate changes in scar appearance and tolerability associated with 8 weeks of use of a test product comprising a topical dexpanthenol ...
Erwan Peltier   +3 more
wiley   +1 more source

The Role of Obstructive Sleep Apnea and CPAP Therapy in the Functional Hypogonadism of Male Patients With Severe Obesity.

open access: yesJ Clin Endocrinol Metab
Amodeo A   +17 more
europepmc   +1 more source

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