Results 41 to 50 of about 144,877 (249)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
eLifeThe gut undergoes peristaltic movements regulated by intricate cellular interactions. How these interactions emerge in the developing gut remains poorly explored due to a lack of model system.
Rei Yagasaki +8 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The Roles of Cortical Slow Waves in Synaptic Plasticity and Memory Consolidation
Frontiers in Neural Circuits, 2017 Sleep plays important roles in sensory and motor memory consolidation. Sleep oscillations, reflecting neural population activity, involve the reactivation of learning-related neurons and regulate synaptic strength and, thereby affect memory consolidation.
Daisuke Miyamoto +3 more
doaj +1 more source
Axioms, 2020 In this work, we present some new sufficient conditions for the oscillation of a class of second-order neutral delay differential equation. Our oscillation results, complement, simplify and improve recent results on oscillation theory of this type of non-
Shyam Sundar Santra +2 more
doaj +1 more source
Physica Scripta, 2006 The inverted harmonic oscillator problem is investigated quantum mechanically. The exact wave function for the confined inverted oscillator is obtained and it is shown that the associated energy eigenvalues are discrete and it is given as a linear function of the quantum number $n$.
Yüce, Cem, Kılıç, Abidin, Coruh, A.
openaire +2 more sources
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Oscillation of Emden–Fowler-Type Neutral Delay Differential Equations
Axioms, 2020 In this work, we consider a type of second-order functional differential equations and establish qualitative properties of their solutions. These new results complement and improve a number of results reported in the literature.
Shyam Sundar Santra +3 more
doaj +1 more source