Results 111 to 120 of about 5,512,868 (262)

PACRG, a protein linked to ciliary motility, mediates cellular signaling. [PDF]

, 2016
Cilia are microtubule-based organelles that project from nearly all mammalian cell types. Motile cilia generate fluid flow, whereas nonmotile (primary) cilia are required for sensory physiology and modulate various signal transduction pathways.
Blacque, Oliver E, Bialas, Nathan J, Walker, D.S. (Denise S.), Schafer, WR, Dekkers, Martijn, Grundy, Laura J, Walker, DS, Li, Chunmei, Bialas, N.J. (Nathan), Walker, Denise S, Inglis, P.N. (P. Nick), Bialas, NJ, Dekkers, MPJ (Martijn), Li, C. (Chunmei), Loucks, CM, Schafer, William R, Inglis, P Nick, Kida, Katarzyna, Blacque, OE, Leroux, Michel R, Leroux, M.R. (Michel), Blacque, O.E. (Oliver), Kida, K. (Katarzyna), Grundy, L.J. (Laura J.), Inglis, PN, Leroux, MR, Kida, K, Loucks, C.M. (Catrina M.), Jansen, Gert, Dekkers, M.P.J. (Martijn), Li, CM, Loucks, Catrina M, Grundy, LJ, Schafer, W.R. (William), Jansen, G. (Gert)   +34 more
core   +2 more sources

Thermoresponsive Liquid Crystalline Polymer Coatings Programmed by Field‐Induced Topological Defects for Tunable Optical and Topographical Responses

Advanced Functional Materials, EarlyView.
Resonant standing waves generate large‐area lattices of liquid‐crystal topological defects that are permanently encoded into polymer coatings by photopolymerization. The preserved director architecture produces thermally reconfigurable surface topographies while maintaining programmable optical functionality, demonstrating a scalable strategy for ...
Jacques A. Peixoto, Mufeeduzaman Chavilkkadan, Alexander Fusi, Marko Beslać, Dirk J. Broer, Etienne Brasselet, Danqing Liu   +6 more
wiley   +1 more source

Targeting Aberrant RAS/RAF/MEK/ERK Signaling for Cancer Therapy

, 2020
The RAS/RAF/MEK/ERK (MAPK) signaling cascade is essential for cell inter- and intra-cellular communication, which regulates fundamental cell functions such as growth, survival, and differentiation.
Ufuk Degirmenci, Jiancheng Hu, Mei Wang
core   +1 more source

An Integrated Oxygen‐Supplying Device and Predictive Multiphysics Model for Extended Ambient Transport of Insulin‐Producing Cells

Advanced Functional Materials, EarlyView.
Cell therapies typically rely on cold‐chain logistics and cryopreservation, limiting access and compromising cell quality. Here, a dual‐chamber device separates an oxygen‐supplying chamber from a hyaluronic acid cargo chamber, sustaining oxygen delivery for over 70 h and enabling ambient‐temperature shipment.
Daniel A. Domingo‐Lopez, Ruth Tarpey, Benjamin Brennan, Bryan D. Boyle, Amir M. Alsharabasy, Abhik Mallick, Gabriella Bellavia, Abhay Pandit, Garry P. Duffy, Ruth E. Levey   +9 more
wiley   +1 more source

Nonlinear time series analysis of nodulation factor induced calcium oscillations: evidence for deterministic chaos?

PLoS ONE, 2009
Legume plants form beneficial symbiotic interactions with nitrogen fixing bacteria (called rhizobia), with the rhizobia being accommodated in unique structures on the roots of the host plant.
Saul Hazledine, Jongho Sun, Derin Wysham, J Allan Downie, Giles E D Oldroyd, Richard J Morris   +5 more
doaj   +1 more source

Fibroblast Growth Factor Receptor Signaling in Skin Cancers

, 2019
Fibroblast growth factor (FGF)/Fibroblast growth factor receptor (FGFR) signaling regulates various cellular processes during the embryonic development and in the adult organism.
Malgorzata Czyz
core   +1 more source

Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis [PDF]

, 2019
Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells, melanocytes, and peripheral neurons and glia during embryonic ...
Chengji J. Zhou, Hao, Hongyan, Yu Ji, Reynolds, Kurt, Kurt Reynolds, McMahon, Moira, Hongyan Hao, Moira McMahon, Ji, Yu, Zhou, Chengji J   +9 more
core   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Acetoacetates Derived From Vegetable Oils: A Platform for Tailor‐Made Vinylogous Urethane Foams

Advanced Functional Materials, EarlyView.
A renewable vegetable oil is converted into acetoacetate‐functionalized precursors for the preparation of catalyst‐free vinylogous urethane foams. Room‐temperature foaming with n‐pentane generates lightweight cellular materials, while the choice of amine enables control over foam structure and mechanical properties.
Krzysztof Polaczek, Priscilla de Souza Lima, Olga Gotkiewicz, Ondrej Kopilec, Radka Hobzova, Lívia Kanizsová, Mikelis Kirpluks, Ondrej Sedlacek, Hynek Beneš   +8 more
wiley   +1 more source

P53 | CIRCADIAN DEPENDENT MOTILITY: THE ROLE FOR THE PERINUCLEAR ACTIN CAP

European Journal of Histochemistry
The circadian rhythm is responsible for the regulation of the daynight cycle by release of several factors, including the master regulator glucocorticoids (GCs). Previous studies reveal that the GCs dampen the transcriptional response to EGFR activation,
doaj   +1 more source