Results 231 to 240 of about 52,144 (290)

Research progress in <i>SYNGAP1</i>-related neurodevelopmental disorders: from pathogenesis to therapeutic strategies. [PDF]

Front Neurol
Zhang J, Xue G, Wang X, Rao X, Chen J, Fan L, Liu L, Gan J.   +7 more
europepmc   +1 more source

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

Advanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat, Laurie O'Neill, Léo Pio‐Lopez, Megan M. Sperry, Patrick Erickson, Tiffany Lin, Michael Levin   +6 more
wiley   +1 more source

Neuronal calcium spikes enable vector inversion in the Drosophila brain. [PDF]

Cell
Ishida IG, Sethi S, Mohren TL, Haraguchi MK, Abbott LF, Maimon G.   +5 more
europepmc   +1 more source

Cellular Snowballing: Cell Adhesion and Migration Drive the Self‐Assembly of Cell‐Microgel Biohybrid Spheroids

Advanced Science, EarlyView.
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie, Sina Kheirabadi, Changhao Li, Aneesh Risbud, Aswathy Sebastian, Istvan Albert, Sulin Zhang, Amir Sheikhi   +7 more
wiley   +1 more source

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model. [PDF]

Adv Sci (Weinh)
Yokomizo S, Maci M, Stafford AM, Miller MR, Perle SJ, Inagaki S, Takahashi S, Brown-Harding H, Liang L, Lovely A, Algamal M, Gillani RL, Zwang TJ, Richardson D, Naegele JR, Vogt D, Kastanenka KV.   +16 more
europepmc   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Mapping auxin dynamics in the formation of lateral roots with a dual-DR5 reporter. [PDF]

Plant Physiol
Reyes-Hernández BJ.
europepmc   +1 more source

Synaptotagmin 5, not synaptotagmin 1, is required for cortical granule exocytosis at fertilization of mouse eggs†. [PDF]

Biol Reprod
Mehlmann LM, Uliasz TF, Lowther KM.
europepmc   +1 more source

Primary cilia regulate GLP-1 signaling in pancreatic β cells. [PDF]

Mol Metab
Melena I, Jo JH, Townsend SE, DiGruccio SA, Dong X, Zhu L, Campbell J, Hughes JW.   +7 more
europepmc   +1 more source