Results 171 to 180 of about 60,818 (269)

Biosynthetic Pathways and Regulation of Antibacterial Compounds From Endophytic Fungi: From Chemistry to Genomics and Biotechnology

open access: yesChemistry &Biodiversity, Volume 23, Issue 11, November 2026.
Endophytic fungi encode abundant cryptic biosynthetic gene clusters that remain largely silent under conventional cultivation. This review highlights how genome mining, multi‐omics, and cluster activation strategies bridge the BGC‐to‐metabolite gap, enabling the discovery of structurally diverse antibacterial natural products with activity against ...
Farkhod Eshboev   +8 more
wiley   +1 more source

The contribution of tear osmolarity measurement to ocular surface assessment in contact lens wearers

open access: yes, 2012
Purpose: To determine whether tear osmolarity using the TearLabTM Osmolarity System contributes to the assessment of the ocular surface in contact lens (CL) wearers.Methods: Data were collected from 44 CL wearers (28 tolerant and 16 intolerant) and 34 ...
Brétillon, Lionel   +7 more
core  

Physical stability of RNA–lipid nanoparticles under agitation, freeze–thaw and accelerated stability testing

open access: yesJournal of Chemical Technology &Biotechnology, Volume 101, Issue 11, Page 2293-2300, November 2026.
Abstract BACKGROUND The choice of excipient is important in enhancing stability of liquid formulations containing lipid nanoparticles (LNPs) used in RNA delivery where the ability to survive unplanned excursions to higher and lower temperature and vibration is an important attribute.
Franz W Laurett Veras   +2 more
wiley   +1 more source

Harnessing the Horse for Human Osteoarthritis: microRNA‐181a‐5p Antisense Oligonucleotides in Clinically Normal Equine Fetlock Joints Are Safe and Well Tolerated

open access: yesJournal of Orthopaedic Research, Volume 44, Issue 11, November 2026.
ABSTRACT Horses serve as a translational model for human osteoarthritis (OA) due to their comparable joint size, cartilage thickness, and incidence of naturally occurring disease. Overexpression of microRNA‐181a‐5p has been implicated in cartilage degradation in OA, and its inhibition using locked nucleic acid antisense oligonucleotides (LNA‐miR‐181a ...
T. Connor McCorkell   +8 more
wiley   +1 more source

Early glucose and sodium trajectories and short-term outcomes in extremely preterm infants. [PDF]

open access: yesFront Pediatr
Gialamas S   +5 more
europepmc   +1 more source

Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 9809-9818, November 2026.
ABSTRACT Context Metabolic syndrome (MetS) is defined by central obesity, insulin resistance, hypertension and dyslipidemia. MetS affects over one‐third of US adults. Beyond its cardiovascular burden, MetS has clinically relevant associations with ocular health and may contribute to a systemic vascular and neuro‐metabolic phenotype involving the retina,
Ron T. Varghese, Ansu A. John
wiley   +1 more source

Tracking Sodium Inside the Plant: Hydraulic Adjustments to Deal With Salinity

open access: yesJournal of Agronomy and Crop Science, Volume 212, Issue 6, November 2026.
ABSTRACT Sorghum is a crop that has become more relevant in recent years due to its uses and properties (biofuel, gluten‐free flour) as well as its versatility to grow in unfavourable environmental conditions. Salinity is one of the main abiotic stresses affecting crop production and yield worldwide.
Moira R. Sutka   +4 more
wiley   +1 more source

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