Results 21 to 30 of about 688 (142)
International Journal of Gynecology &Obstetrics, Volume 162, Issue 3, Page 1042-1049, September 2023., 2023 Abstract Objective To evaluate the effect of iatrogenic menopause on the physiology of the vagina of the ewe and to evaluate if vaginal changes in ewes can be translated to women with genitourinary syndrome of menopause (GSM). Methods Preclinical research with Dohne Merino ewes. Iatrogenic menopause was induced by bilateral ovariectomy (OVX).
Eva V. Vodegel +8 more
wiley +1 more source
Drugs in Context, 2020 Women with breast cancer are at a higher risk of developing vulvar and vaginal atrophy (VVA), a major component of the genitourinary syndrome of menopause, due to the combined estrogen-depleting effects of chemotherapy, adjuvant hormone therapy, and ...
Mariella Lilue +2 more
doaj +1 more source
Clinical and Translational Medicine, Volume 13, Issue 7, July 2023., 2023 Repurposed drugs and drug delivery systems could help overcome immunosuppression induced by cancer. Drugs unveiled to have immunostimulatory effects in cancer treatment span multiple categories. Well‐designed structures and rational cargos enable delivery systems to stimulate the anticancer immune response.
Zile Fu +4 more
wiley +1 more source
Drugs in Context, 2020 The pathophysiological changes associated with hypoestrogenism of menopause, a condition known as genitourinary syndrome of menopause, are responsible for the hallmark symptoms of vulvovaginal atrophy (VVA), namely dyspareunia secondary to vaginal ...
Ana Rosa Jurado López +1 more
doaj +1 more source
Mechanistic advances in osteoporosis and anti‐osteoporosis therapies
MedComm, Volume 4, Issue 3, June 2023., 2023 Osteoporosis, a type of bone loss disease, causes enormous burden at both the human and socioeconomic layer. In this study, we systematically reviewed according literatures and clinical evidences to both mechanistically and clinically demonstrate the state‐of‐art advances on osteoporosis, and furthermore present the most updated anti‐osteoporosis ...
Haiwei Wang +5 more
wiley +1 more source
Experience with ospemifene in a patient with vulvovaginal atrophy and dyslipidemia: a case study
Drugs in Context, 2020 The changes that occur in sex hormone levels, body composition, and lipid/lipoprotein levels during the menopause transition, together with vascular remodeling, increase the risk of cardiovascular disease (CVD) in postmenopausal women.
Silvia Pilar González Rodríguez
doaj +1 more source
Chemistry – A European Journal, Volume 29, Issue 18, March 28, 2023., 2023 A key reagent to introduce trifluoroethylene: A protocol for the connection of alcohols and (hetero)arenes via a trifluoroethylene linker has been developed. Key for the development of this procedure has been the synthesis of a sulfonium salt bearing a trifluorovinyl substituent.
Zeyu Feng +8 more
wiley +1 more source
Current treatment options for genitourinary syndrome
Медицинский совет, 2020 At the onset of menopause, the urogenital symptoms begin to develop simultaneously with vasomotor symptoms: vaginal soreness, itching and dryness, dyspareunia, etc.
E. V. Tikhomirova +2 more
doaj +1 more source
European Journal of Cancer Care, Volume 2023, Issue 1, 2023., 2023 Objective. To assess the sexual health and interest of breast cancer survivors (BCSs) in a tailored evaluation of their sexuality. Methods. A descriptive analysis on baseline sexual assessment of female BCS with genitourinary syndrome of menopause (GSM) receiving aromatase inhibitors (AIs), who have participated on an ongoing double‐blinded randomized ...
Sònia Anglès-Acedo +8 more
wiley +1 more source
Menopause, skin and common dermatosis. Part 3: genital disorders
Clinical and Experimental Dermatology, Volume 47, Issue 12, Page 2123-2129, December 2022., 2022 The low oestrogen levels during menopause lead to physical and physiological changes to the female genitourinary tract. This can lead to the characteristic changes known as genitourinary syndrome of menopause (GSM). The symptoms and signs of GSM can overlap or coexist with other vulval dermatoses.
Esra Musbahi +3 more
wiley +1 more source