Results 71 to 80 of about 688 (142)

Effect of Ospemifene on Densitometric and Plasma Bone Metabolism Biomarkers in Postmenopausal Women Reporting Vulvar and Vaginal Atrophy (VVA)

, 2022
Menopausal hormone deficiency can exert multiple effects on various organs. Vulvovaginal atrophy (VVA) is among the most widespread and disabling post-menopausal disorder.
Maffei, Silvia, Silvia Maffei, Letizia Guiducci, Guiducci, Letizia   +3 more
core   +1 more source

Retrospective analysis in 46 women with vulvovaginal atrophy treated with ospemifene for 12 weeks. improvement in overactive bladder symptoms

, 2017
The aim of this study was to assess the effectiveness and safety of Ospemifene in the improvement of urgency component in women affected by mixed urinary incontinence (MUI) who underwent surgery with mid-urethral sling (MUS). Eighty-one patients with MUI
Violante Di Donato, Giorgia Perniola, Giovanni Prata, Schiavi, MICHELE CARLO, Ottavia D’Oria, Colagiovanni, Vanessa, Zullo, Marzio Angelo, Chiara Di Tucci, Marco Monti, Vanessa Colagiovanni, Perniola, Giorgia, Faiano, Pierangelo, Monti, Marco, D' Oria Ottavia, Pierluigi Benedetti Panici, Ludovico Muzii, Muzii, Ludovico, Michele Carlo Schiavi, Prata, Giovanni, DI TUCCI, Chiara, BENEDETTI PANICI, Pierluigi, Pierangelo Faiano, Andrea Giannini, DI DONATO, Violante, Marzio Angelo Zullo, Giannini, Andrea   +25 more
core   +1 more source

Overactive bladder syndrome treatment with ospemifene in menopausal patients with vulvovaginal atrophy. improvement of sexuality?

, 2018
The aim of this study was to assess the effectiveness of ospemifene in the improvement of sexual function in postmenopausal women with vulvovaginal atrophy (VVA) affected by overactive bladder syndrome (OAB) or urge urinary incontinence (UUI).
Sciuga, Valentina, Di Tucci, Chiara, Meggiorini, Maria Letizia, Valentina Sciuga, Schiavi, Michele Carlo, Giovanni Prata, Natalia Aleksa, Carmela Capone, Benedetti Panici, Pierluigi, Flaminia Vena, Savone, Delia, Di Mascio, Daniele, Zullo, Marzio Angelo, Delia Savone, Daniele Di Mascio, D'oria, Ottavia, Chiara Di Tucci, GIANNINI, ANDREA, Ottavia D’oria, Marco Monti, Capone, Carmela, VENA, FLAMINIA, Monti, Marco, Maria Letizia Meggiorini, Pierluigi Benedetti Panici, Ludovico Muzii, Muzii, Ludovico, Michele Carlo Schiavi, Prata, Giovanni, ALEKSA, NATALIA, Andrea Giannini, Marzio Angelo Zullo   +31 more
core   +1 more source

Differential effects of selective oestrogen receptor modulators (SERMs) tamoxifen, ospemifene and raloxifene on human osteoclasts in vitro

, 2007
Background and purpose: Several selective oestrogen receptor modulators ( SERMs) with oestrogen agonist effects in bone cells and without increased risk of breast and endometrial cancer have been developed.
Vaananen, H. K., H K Väänänen, Kangas, L., Hentunen, T. A., L Kangas, Härkönen, Pirkko,, Michael, H., H Michael, T A Hentunen, Lund University., P L Härkönen, Härkönen, Pirkko   +11 more
core   +1 more source

Usefulness of Ospemifene in the treatment of urgency in menopausal patients affected by mixed urinary incontinence underwent mid-urethral slings surgery

, 2018
The aim of this study was to assess the effectiveness and safety of Ospemifene in the improvement of urgency component in women affected by mixed urinary incontinence (MUI) who underwent surgery with mid-urethral sling (MUS). Eighty-one patients with MUI
Sciuga, Valentina, Di Tucci, Chiara, Meggiorini, Maria Letizia, Schiavi, Michele Carlo, Monti, Marco, Vena, Flaminia, Benedetti Panici, Pierluigi, D’Oria, Ottavia, Muzii, Ludovico, Prata, Giovanni, Savone, Delia, Zullo, Marzio Angelo, Aleksa, Natalia, Giannini, Andrea   +13 more
core   +1 more source

Pharmacokinetics, pharmacodynamics and clinical efficacy of ospemifene for the treatment of dyspareunia and genitourinary syndrome of menopause

, 2016
Ospemifene is a selective estrogen receptor modulator recently approved by the FDA for the treatment postmenopausal women experiencing moderate-to-severe dyspareunia and by the EMA for the treatment of moderate-to-severe symptomatic genitourinary ...
FERRERO, SIMONE, RACCA, ANNALISA, LEONE ROBERTI MAGGIORE, UMBERTO, SCALA, CAROLINA, Bondi, Chiara, VENTURINI, PIER LUIGI, TAFI, EMANUELA   +6 more
core   +1 more source

Prevention of recurrent lower urinary tract infections in postmenopausal women with genitourinary syndrome. outcome after 6 months of treatment with ospemifene

, 2017
Aim of this study was to evaluate the efficacy of ospemifene in the prevention of recurrent lower urinary tract infections in postmenopausal women with vulvovaginal atrophy. The study have a retrospective design.
Sciuga, Valentina, Angela Martoccia, Di Tucci, Chiara, Di Pinto, Anna, Valentina Sciuga, Schiavi, Michele Carlo, Giovanni Prata, Benedetti Panici, Pierluigi, Ostuni, Rosa, Zullo, Marzio Angelo, Chiara Di Tucci, Ottavia D’oria, Rosa Ostuni, Dâ€TMoria, Ottavia, Faiano, Pierangelo, Anna Di Pinto, Pierluigi Benedetti Panici, Ludovico Muzii, Martoccia, Angela, Carlo Carraro, Muzii, Ludovico, Michele Carlo Schiavi, Prata, Giovanni, Pierangelo Faiano, Carraro, Carlo, Marzio Angelo Zullo   +25 more
core   +1 more source

The role of drug metabolism in drug discovery and development:case ospemifene

, 2015
Drug metabolism is one of the most important events a drug faces after administration. Traditionally, drug metabolism has only been considered as a major clearance and elimination step in the pharmacokinetics of a drug.
Uusitalo, J. (Jouko)
core  

Efficacy, tolerability, and endometrial safety of ospemifene compared with current therapies for the treatment of vulvovaginal atrophy: a systematic literature review and network meta-analysis. [PDF]

Menopause, 2023
Simon JA, Ferenczy A, Black D, Castonguay A, Royer C, Marouf R, Beauchemin C.   +6 more
europepmc   +1 more source

Posttreatment with Ospemifene Attenuates Hypoxia- and Ischemia-Induced Apoptosis in Primary Neuronal Cells via Selective Modulation of Estrogen Receptors. [PDF]

Neurotox Res, 2023
Pietrzak BA, Wnuk A, Przepiórska K, Łach A, Kajta M.   +4 more
europepmc   +1 more source