Results 161 to 170 of about 9,199 (246)

Oral Streptococcus salivarius Couples Neutrophil IRGM1 Signaling to NET Formation and Colorectal Cancer Metastasis

Advanced Science, EarlyView.
The oral bacterium Streptococcus salivarius promotes colorectal cancer metastasis by inducing neutrophil extracellular trap (NET) formation. Mechanistically, IRGM1–IQGAP1 interaction activates Wnt5a–PI3K/AKT signaling in neutrophils, driving NET‐mediated tumor progression.
Fengyi Liu, Yuan Wang, Hengxuan Cai, Qianwen Yue, Xueli Liu, Xuanwen Bao, Zeng Wang, Xuehan Li, Lai Wei, Zhihua Zhang, Fan Xing, Yi Xu, Xianjun Li, Wei Xu   +13 more
wiley   +1 more source

Deep learning reconstruction of zero-echo time sequences to improve visualization of osseous structures and associated pathologies in MRI of cervical spine. [PDF]

Insights Imaging
Kaniewska M, Zecca F, Obermüller C, Ensle F, Deininger-Czermak E, Lohezic M, Guggenberger R.   +6 more
europepmc   +1 more source

Developmentally Inspired, Mechanical–Metabolic Dual Gradient Osteochondral Constructs Bridging Regeneration and Therapeutic Screening

Advanced Science, EarlyView.
A developmentally inspired osteochondral construct integrates mechanical and metabolic dual gradients within a 3D‐printed platform. Human MSC spheroids are spatially directed to form cartilage–bone interfaces, enabling evaluation of regeneration without biochemical reagents and assessment of drug responses. This physiologically relevant, phase‐specific
Yurim Choi, Wonjun Jang, Raehui Kang, Ulziituya Batjargal, Jihyeon Song, Soojin Park, MinSeok Kim, Hyobum Cho, Junhyung Kim, Yu Shrike Zhang, Han‐Jun Kim, Junmin Lee   +11 more
wiley   +1 more source

The Value of Histopathological and Clinical Characteristics for the Assessment of the Prognosis and the Efficacy of Dynamic Anterior Stabilization Surgical Treatment for Shoulder Instability. [PDF]

Diagnostics (Basel)
Finogejevs A, Jumtiņš A, Moritis ET, Isajevs S.   +3 more
europepmc   +1 more source

Posttraumatic rotation deficit of the forearm, including synostosis [PDF]

, 2012
Hollevoet, Nadine, KEGELS, LORE, Vanhove, Wim   +2 more
core   +1 more source

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

Validation and feasibility of a deep learning-based reconstruction technology in 5.0 tesla knee joint MR imaging. [PDF]

Front Radiol
Wang P, Li Z, Zhu C, Mu R, Liu C, Yang J, Du L.   +6 more
europepmc   +1 more source

Collagen and Chondroitin Sulfate Xenogeneic Implants in Primates: A Sequential Histopathologic Study [PDF]

, 1975
Skinner, Raymond Alister
core  

Targeted Extracellular Vesicles Deliver Asiaticoside to Inhibit AURKB/DRP1‐Mediated Mitochondrial Fission and Attenuate Hypertrophic Scar Formation

Advanced Science, EarlyView.
Hypertrophic scar formation is driven by excessive mitochondrial fission in wound macrophages, which we discover is governed by a novel AURKB‐DRP1(Ser616) axis. The study develops a targeted therapy using cRGD‐decorated extracellular vesicles to deliver the natural compound Asiaticoside specifically to macrophages.
Luyu Li, Chenli Si, Xue Wang, Xiaojin Wu, Ying Shang, Shengfang Ge, Yong Wang, Yong Zuo, Zhen Zhang   +8 more
wiley   +1 more source

[¹⁸F]SiTATE PET for PRRT selection and monitoring metastatic tumors of the adrenal medulla and extra-adrenal paraganglia. [PDF]

Eur J Nucl Med Mol Imaging
Siegmund SC, Holzgreve A, Schöll M, Wenter VU, Sheikh GT, Scheifele M, Gildehaus FJ, Lindner S, Auer MK, Lottspeich C, Kroiß M, Nölting S, Völter F, Spitzweg C, Auernhammer CJ, Werner RA, Zacherl MJ.   +16 more
europepmc   +1 more source