Results 161 to 170 of about 4,299 (193)

Inhibition of KDEL Receptors Remodels the Tumor Microenvironment for T Cell Independent Tumor Regression

Advanced Science, EarlyView.
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak, Hong Wang, Belinda Willard, Timothy A. Chan, William C Merrick, Zheng‐Rong Lu, Boaz Tirosh   +6 more
wiley   +1 more source

Undifferentiated pelvic sarcoma 5 years post-radiochemotherapy for rectal adenocarcinoma: A case report. [PDF]

Oncol Lett
Yang Y, Long Y.
europepmc   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

Beam-hardening correction in clinical x-ray dark-field chest radiography using deep-learning-based bone segmentation. [PDF]

Med Phys
Kaster L, Lochschmidt ME, Bauer AM, Dorosti T, Demianova S, Koehler T, Pfeiffer D, Pfeiffer F.   +7 more
europepmc   +1 more source

RNA‐Binding Protein RBM25 Targets the mRNA Stability of GTPase Rab22a to Restrict Viral Entry and Infection

Advanced Science, EarlyView.
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding, Huiying Chen, Yuyu Jiang, Chunyan Zhao, Jie Bai, Yan Xiang, Zeting Wang, Xixi Wang, Bing Rui, Wanda Tang, Yue Ding, Zhenzhen Zhan, Yunkai Zhang, Xingguang Liu   +13 more
wiley   +1 more source

Deep learning reconstruction of zero-echo time sequences to improve visualization of osseous structures and associated pathologies in MRI of cervical spine. [PDF]

Insights Imaging
Kaniewska M, Zecca F, Obermüller C, Ensle F, Deininger-Czermak E, Lohezic M, Guggenberger R.   +6 more
europepmc   +1 more source

Effects of High-Velocity Elbow Manipulation on Forearm Muscle Electromyographic Recovery in Karting Drivers: A Randomized Within-Participant Sham-Controlled Trial. [PDF]

J Clin Med
Studnicki R, Zarembski A, Wasilewska J, Trąbka B.   +3 more
europepmc   +1 more source

Integrated diagnostic evaluation of multiple malignant neoplasms via ^99mTc-MDP three-phase bone imaging: A case report. [PDF]

Oncol Lett
Lian JY, Lu JL, Zheng HY, Yuan SX, Zhang JS.   +4 more
europepmc   +1 more source

Quantification of Costal Cartilage Calcification Using ¹⁸F-NaF-PET/CT. [PDF]

J Imaging
Shehu V, Gandhi OH, Glennan P, Gujral J, Singh SB, Amanullah AA, Patil S, Gujral K, Raynor WY, Park PSU, Teichner EM, Subtirelu RC, Khan T, Werner TJ, Høilund-Carlsen PF, Gholamrezanezhad A, Revheim ME, Alavi A.   +17 more
europepmc   +1 more source

Explainable machine learning identifies knee morphology thresholds for arthroscopic medial meniscus posterior root tear: a retrospective cohort study. [PDF]

Front Med (Lausanne)
Zhang M, Guo F, Li Y, Zheng J, Yu Y, Chen M, Li R, Liao Y, Chen Q, He C.   +9 more
europepmc   +1 more source