Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis
DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li +16 more
wiley +1 more source
Injectable and Assembled Calcium Sulfate/Magnesium Silicate 3D Scaffold Promotes Bone Repair by In Situ Osteoinduction. [PDF]
Zhu W +8 more
europepmc +1 more source
Pressure knapping west of the Rhine during the Mesolithic? New evidence from Kerkhove (Belgium). [PDF]
Vandendriessche H, Guéret C.
europepmc +1 more source
Influence of Intra-Articular Tunnel Aperture Morphology on Clinical Outcomes and Graft Rerupture After ACL Reconstruction. [PDF]
Iyetin Y +4 more
europepmc +1 more source
C1QTNF1-AS1/miR-346 axis suppresses osteosarcoma progression via dual inhibition of LDHA/PDK1-mediated Warburg effect. [PDF]
Zhang Y +7 more
europepmc +1 more source
Comparison of the exposure of the distal tibial articular surface for posterior pilon fractures via a medial or lateral malleolar osteotomy: a preliminary cadaveric study. [PDF]
Yang F +7 more
europepmc +1 more source
This paper asses changes in the exploitation of osseous raw material (namely deer antler) during the early Upper Palaeolithic in Europe. Through examining four variables; raw material procurement, blank production, object manufacture and equipment maintenance, the author establishes that the complex and innovative working of osseous materials is ...
José-Miguel Tejero
openalex +3 more sources

