Results 211 to 220 of about 9,199 (246)

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

Comparison of incisive canal remodeling and root resorption in extraction vs. non-extraction fixed orthodontic retraction: a CBCT study. [PDF]

Front Physiol
Al-Rokhami RK, Gao D, Dang X, Jiang R, Zhang G, Sakran KA.   +5 more
europepmc   +1 more source

Epithelioid and spindle cell rhabdomyosarcoma of the rib with FUS-TFCP2 fusion: A case report and literature review. [PDF]

Oncol Lett
Ye D, Wu M, Zong J, Zeng W, Yan G, Zhou J, Wang W.   +6 more
europepmc   +1 more source

Rigid locked antegrade versus retrograde intramedullary nailing in treating acute humeral shaft fractures: a systematic review with meta-analysis. [PDF]

EFORT Open Rev
Lanuza Lagunilla L, Muriel García A, Díaz Heredia J, Ruiz Díaz R, González Sastre V, Ruiz Ibán MÁ.   +5 more
europepmc   +1 more source

On the technology of late Aurignacian burin and scraper production, and the importance of the Paviland lithic assemblage and the Paviland burin. [PDF]

, 2008
Dinnis, Rob
core  

Evaluating the efficacy of eggshell-derived hydroxyapatite (EHA) and synthetic hydroxyapatite (SHA) in bone regeneration of maxillofacial defects-a randomized double-blind pilot comparative clinical-radiological study. [PDF]

J Oral Biol Craniofac Res
Changani K, Managutti A, Menat S, Patel N, Kattimani V, Panchal D, Girija EK.   +6 more
europepmc   +1 more source

First stage in technological production of Stone Age animal teeth pendants: evidence from Zvejnieki (Latvia) and wider social implications. [PDF]

Archaeol Anthropol Sci
Macāne A, Nordqvist K, Mannermaa K, Needham A, Pomstra D, Alcobendas GC, Reblis J, Zagorska I, Little A.   +8 more
europepmc   +1 more source

Endodontic bioceramics: current and futurity aspects. [PDF]

Front Oral Health
M R, Shetty K, Mallya L, Shetty KP.
europepmc   +1 more source

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Osseous raw material exploitation and typological varyability at mesolitic Alibeg (the Iron Gates region, Romania)

2017
The Mesolithic settlements in the Iron Gates have yielded rich assemblages of antler, bone and Sus scrofa canines, exemplified here by the site of Alibeg (Romania). These raw materials represent for the Iron Gates region, a hallmark of local Mesolithic. The typological categories identified are bevelled tools, scrapers, preforms and blanks.
Boroneanţ Adina, Mărgărit Monica
openaire   +1 more source