Results 111 to 120 of about 23,011 (327)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Meniscal ossicle

open access: yes, 2019
Clinical History: A 29-year-old man presents with left knee pain after a bicycle fall 10 days prior, with occasional locking feeling and knee instability.
openaire   +2 more sources

Ossicle variation in Antarctic dendrochirote holothurians (Echinodermata) [PDF]

open access: yes, 1994
A study of ossicle variation in Cucumariidae coming from the Weddell Sea (antarctica), the specimens ranging from 4 to 70 mm long, confirms that Heterocucumis steineni (Ludwig, 1898), Heterocucumis antarctica (Vaney, 1906) and Heterocucumis godfroyi ...
Massin, C.
core  

Xenosaurus [PDF]

open access: yes, 2000
Number of Pages: 3Integrative BiologyGeological ...
Ballinger, Royce E.   +2 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Evaluation of 4 Outcomes Measures in Microtia Treatment: Exposures, Infections, Aesthetics, and Psychosocial Ramifications. [PDF]

open access: yes, 2017
BackgroundIn craniofacial microsomia, microtia and canal atresia pose formidable reconstructive challenges. We review our institutional experience in treating microtia and atresia to identify variables associated with 4 outcomes measures: complications ...
Bradley, James P   +7 more
core  

In vivo imaging of middle-ear and inner-ear microstructures of a mouse guided by SD-OCT combined with a surgical microscope [PDF]

open access: yes, 2014
We developed an augmented-reality system that combines optical coherence tomography (OCT) with a surgical microscope. By sharing the common optical path in the microscope and OCT, we could simultaneously acquire OCT and microscope views.
Casselman   +25 more
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Redescription of Psolus tessellatus Koehler, 1896 (Echinodermata, Holothuroidea) with neotype designation [PDF]

open access: yes, 2013
In the bycatch of a scientific campaign in the Bay of Biscay (VITAL 2002) a third specimen of Psolus tessellatus Koehler, 1896 was collected very close to the type locality.
Massin, Claude
core   +3 more sources

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