Results 121 to 130 of about 23,011 (327)
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
BioMed Research International, 2015 Chronic inflammation, which is caused by recurrent infections, is one of the factors contributing to the pathogenesis of cholesteatoma. If reimplantation of autologous ossicles after a surgical intervention is intended, inactivation of planktonic ...
W. Masanta, R. Hinz, A. Zautner
semanticscholar +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Artificial Keys to the Genera of Living Stalked Crinoids (Echinodermata) [PDF]
, 2002 Two practical, illustrated, dichotomous keys to the 29 genera of living stalked crinoids are provided: one for entire animals and one for stalk ossicles and fragments. These are accompanied by (1) an overview of taxonomically important morphology, and (2)
Améziane, Nadia +2 more
core +1 more source
Nonbreeding Eastern Curlews Numenius madagascariensis Do Not Increase the Rate of Intake or Digestive Efficiency before Long-Distance Migration because of an Apparent Digestive Constraint [PDF]
, 2003 The possibility of premigratory modulation in gastric digestive performance was investigated in a long-distance migrant, the eastern curlew (Numenius madagascariensis), in eastern Australia.
Skilleter, Gregory A., Zharikov, Yuri
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
A Contribution to the Anatomy and Physiology of the Air-Bladder and Weberian Ossicles in Cyprinidae
, 1925 The Swim-bladder or Air-bladder of Fish is situated within the abdominal cavity between the alimentary canal and the vertebral column, but without the sac of the peritoneum which covers only its ventral portion.
H. M. Evans
semanticscholar +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Burial Data from Hacımusalar Höyük (Turkey) [PDF]
, 2015 This deposit contains data derived from osteological analyses of human skeletons excavated from the archaeological site of Hacımusalar Höyük (ancient Choma) in Turkey. Analyses were performed by Carrie L.
Sulosky Weaver, Carrie L
core