The dual role of CCND1 in heterotopic ossification: A Non-canonical Pathway for Celecoxib treatment
Objective: To explore the effective targets of Celecoxib in the treatment of heterotopic ossification using network pharmacology methods. Methods: Potential molecules related to heterotopic ossification were obtained by retrieving the GEO and CTD ...
Wei Liu+8 more
doaj
Heterotopic Ossification in Vertebral Interlaminar/Interspinous Instrumentation: Report of a Case
We present here a rare case of heterotopic ossification in interspinous/interlaminar Coflex device. The classical surgical indications for these implants are degenerative canal stenosis, discogenic low back pain, disk herniations, facet syndrome, and ...
Giuseppe Maida+2 more
doaj +1 more source
Use of Imatinib in the Prevention of Heterotopic Ossification [PDF]
Background: Heterotopic ossification (HO) is a common complication following orthopedic and trauma surgery, which may have substantial negative effects on the postoperative outcome. Angiogenesis appears to play a critical role in heterotopic ossification.
Lane, Joseph+5 more
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Altered macrophage infiltration upon tissue damage results in inadequate healing due to inappropriate remodeling and stem cell recruitment and differentiation.
M. Tirone+12 more
semanticscholar +1 more source
MASSIVE POSTTRAUMATIC HETEROTOPIC OSSIFICATION OF KNEE JOINT (CASE REPORT)
Heterotopic ossification is characterized by bone tissue formation in soft tissues that possess no osteogenic properties. The authors present a clinical case of a female patient with massive heterotopic ossification in anteromedial aspect of the right ...
M. S. Ryazantsev+6 more
doaj +1 more source
Heterotopic ossification in systemic sclerosis
Although myopathy or myositis may occur in systemic sclerosis (SSc) as well as soft tissue calcification, ossification is not a feature of the disease. Here we present an unusual case of extended calcification and, to a lesser degree, ossification of the right gluteal region, lateral thigh, and knee, with associated myopathy and functional impairment ...
Botzoris, V.+4 more
openaire +3 more sources
Heterotopic Ossification in Orthopaedic and Trauma surgery: A Histopathological Ossification Score
Heterotopic Ossification (HO) is a potential long-term complication in orthopaedic surgery. It is commonly classified according to the Brooker classification, which is based on radiological findings.
M. Ohlmeier+5 more
semanticscholar +1 more source
Use of Calcitonin in Recalcitrant Phantom Limb Pain Complicated by Heterotopic Ossification
A common complication following amputation is phantom sensation, which may include experiencing pain in the phantom limb. This study details the management of phantom limb pain in a 72-year-old man, in whom comorbid heterotopic ossification was present ...
Ricardo Viana, Michael WC Payne
doaj +1 more source
Challenges of heterotopic ossification—Molecular background and current treatment strategies
Heterotopic ossification (HO) is an abnormal formation of mature lamellar bone within extraskeletal soft tissues, such as muscles, tendons, and ligaments. This process is thought to be induced by inflammation associated with tissue injuries.
P. Łęgosz+4 more
semanticscholar +1 more source
Osificaciones heterotópicas tras artroplastia total primaria de rodilla [PDF]
Introducción. La osificación heterotópica tras artroplastia total de rodilla primaria es una complicación poco estudiada. Nos propusimos estudiar su incidencia en la serie de prótesis totales de rodilla de nuestro hospital, y su posible repercusión ...
Cabanes, F., Sangüesa, M. J.
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