Results 21 to 30 of about 12,632 (137)

The dual role of CCND1 in heterotopic ossification: A Non-canonical Pathway for Celecoxib treatment

Heliyon
Objective: To explore the effective targets of Celecoxib in the treatment of heterotopic ossification using network pharmacology methods. Methods: Potential molecules related to heterotopic ossification were obtained by retrieving the GEO and CTD ...
Wei Liu, Junchao Huang, Jianhai Hu, Ziheng Bu, Zheng Zhou, Jianing Yu, Huajun Wang, Xinbo Wu, Peng Wu   +8 more
doaj   +1 more source

Extensive Circumferential Heterotopic Ossification Discovered at the Base of a Loop Ileostomy

Case Reports in Surgery, 2019
Heterotopic ossification is a rare phenomenon defined by the formation of bone within nonossifying soft tissues. A rare variant of heterotopic ossification is heterotopic mesenteric ossification (HMO), in which there is involvement of the mesentery and ...
Ahmad Bosaily, John Edminister, Samarchitha Magal, Mohammad Jamil, Amy Lynn, Glenn Hall   +5 more
doaj   +1 more source

Immunological and morphological analysis of heterotopic ossification differs to healthy controls

BMC Musculoskeletal Disorders, 2018
Background Formation of lamellar bone in non-osseus tissue is a pathological process called heterotopic ossification. It is the aim of this study to analyse the morphology and immunological status of patients with heterotopic ossification compared to ...
Klemens Trieb, Andreas Meryk, Sascha Senck, Erin Naismith, Beatrix Grubeck-Loebenstein   +4 more
doaj   +1 more source

Use of Acellular Dermal Matrix to Prevent Recurrence of Radioulnar Heterotopic Ossification

Plastic and Reconstructive Surgery, Global Open, 2019
Summary:. Radioulnar heterotopic ossification is a rare occurrence found in approximately 2% of all forearm injuries. Treatment is complicated by relatively high recurrence rates.
Daniel J. Gould, MD, PhD, Paymon Rahgozar, MD, Eric S. Nagengast, MD, David A. Kulber, MD   +3 more
doaj   +1 more source

Improvements in Patient‐Reported Outcomes and Few Reported Major Complications Following Hip Arthroscopy in Patients With Femoroacetabular Impingement Syndrome: A Systematic Review

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To systematically review the literature to evaluate complications and patient‐reported outcome measures (PROMs) after hip arthroscopy in patients with femoroacetabular impingement syndrome. Methods Five databases were searched for studies reporting complications and PROMs after hip arthroscopy in patients with femoroacetabular impingement ...
Frederik Nicolai Foldager, Julius David, Lisa Urup Tønning, Bjarne Mygind‐Klavsen, Christian Gatzka, Barbara Zimmerman, Inger Mechlenburg   +6 more
wiley   +1 more source

Severity of heterotopic ossification in patients following surgery for hip fracture: a retrospective observational study

BMC Musculoskeletal Disorders, 2019
Background Heterotopic ossification (HO) is a relatively common complication following hip surgery treated with open reduction and internal fixation, total arthroplasty or hemiarthroplasty.
Daichi Hayashi, Elaine S. Gould, Corey Ho, Dennis L. Caruana, David E. Komatsu, Jie Yang, Chencan Zhu, Musa Mufti, James Nicholson   +8 more
doaj   +1 more source

Dual Labral and Ligamentum Teres Reconstruction Achieves High Functional Outcomes and Arthroplasty‐Free Survivorship at 2 Years

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate the clinical outcomes and survivorship of hip arthroscopy with simultaneous labral and ligamentum teres (LT) reconstruction for the treatment of irreparable labral and LT tears, with a minimum follow‐up of 2 years. Methods Prospectively collected data were retrospectively reviewed for patients who underwent combined arthroscopic ...
Roger Quesada‐Jimenez, Krishi Rana, Matthew J. Strok, Ady H. Kahana‐Rojkind, Alexander K. Burt, Etan P. Sugarman, Benjamin G. Domb   +6 more
wiley   +1 more source

Peripheral inflammatory T cell subsets are effective predictive factors in the development of heterotopic ossification after posttraumatic elbow surgery

Heliyon
Heterotopic ossification refers to the pathological formation of extra-skeletal bone. It is a common complication of trauma or surgery that can cause disability and has no definitive cure.
Zengfeng Xin, Junhua Chen, Fengbo Huang, Siyu Guo, Yihan Yao, Yang Tang, Hang Li, Qinghua Lv, Ting Zhang   +8 more
doaj   +1 more source

A follow-up report on the published paper Social and clinical impact of COVID-19 on patients with fibrodysplasia ossificans progressiva

Orphanet Journal of Rare Diseases, 2023
Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder associated with increased immune activity and severe, progressive heterotopic ossification.
Hayley Wallace, Rhonda H. Lee, Edward C. Hsiao   +2 more
doaj   +1 more source

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source