Results 21 to 30 of about 6,433 (134)

A Functional RNAi Screen for Runx2-Regulated Genes Associated With Ectopic Bone Formation in Human Spinal Ligaments

Journal of Pharmacological Sciences, 2008
Ossification of the posterior longitudinal ligament of the spine (OPLL) is characterized by ectopic ossification in the spinal ligaments, which enlarges with time and compresses the spinal cord, resulting in serious neurological symptoms.
Masaki Kishiya, Toshitada Sawada, Kohta Kanemaru, Hitoshi Kudo, Takuya Numasawa, Toru Yokoyama, Sunao Tanaka, Shigeru Motomura, Kazumasa Ueyama, Seiko Harata, Satoshi Toh, Ken-Ichi Furukawa   +11 more
doaj   +1 more source

Non-coding RNAs in ossification of the posterior longitudinal ligament

Frontiers in Genetics, 2022
Ossification of the posterior longitudinal ligament (OPLL) is a kind of disease that involves a variety of factors leading to ectopic bone deposition of the spinal ligament.
Haoran Zhang, Qingyu Zhang, Zenong Yuan, Jun Dong   +3 more
doaj   +1 more source

Clinical Efficacy of Endoscopic-Assisted Resection of Single-Segment Ossification of the Posterior Longitudinal Ligament in the Treatment of Thoracic Spinal Stenosis

Frontiers in Surgery, 2022
ObjectiveTo explore the clinical efficacy, characteristics and safety of endoscopic-assisted resection of single-segment posterior longitudinal ligament ossification in the treatment of thoracic spinal stenosis (TSS).MethodFifteen TSS patients, including
Xingchen Li, Honghan Huang, Zhong Zheng, Yunxuan Liu, Guicai Wei, Xiaoxin Chen, Yusheng Xu   +6 more
doaj   +1 more source

Lumbar ossification of the ligamentum flavum reflects a strong ossification tendency of the entire spinal ligament

Scientific Reports, 2023
Patients with ossification of the ligamentum flavum (OLF) in the lumbar spine may be at high risk of developing concomitant ossification of the entire spinal ligament, but the etiology remains unclear.
Kazuha Nakabachi, Tsutomu Endo, Masahiko Takahata, Ryo Fujita, Yoshinao Koike, Ryota Suzuki, Yuichi Hasegawa, Toshifumi Murakami, Katsuhisa Yamada, Hideki Sudo, Mohamad Alaa Terkawi, Ken Kadoya, Norimasa Iwasaki   +12 more
doaj   +1 more source

Histological analysis of the spatio‐temporal development of porcine knee cartilage in embryonic and early postnatal stages

Animal Models and Experimental Medicine, EarlyView.
This study dynamically charts the developmental process of the knee joint cartilage from the embryonic stage through to postnatal life, revealing key developmental events including the origin of knee joint development, chondrification, primary ossification, secondary ossification, formation of the cartilage cancal, and formation of the growth plate. It
Yan Nie, Kai Wang, Xuewen Wang, Jinzhu Jing, Zhen Liang, Guoqiang Yan, Wen Feng Guo, Meng Zhang, Wei Zhang, Lei Xiang   +9 more
wiley   +1 more source

Spinal hypermobility accelerates ossification in posterior longitudinal ligaments: insights from an in vivo mouse model

Frontiers in Physiology
IntroductionOssification of the posterior longitudinal ligaments (OPLL) is characterized by heterotopic ossification in the posterior longitudinal ligament of spine.
Tao Tang, Tao Tang, Zhengya Zhu, Zhengya Zhu, Zhongyuan He, Zhongyuan He, Fuan Wang, Lin Chen, Jianfeng Li, Hongkun Chen, Jiaxiang Zhou, Jianmin Wang, Shaoyu Liu, Yunfeng Yao, Xizhe Liu, Zhiyu Zhou   +15 more
doaj   +1 more source

Current Topics in Pharmacological Research on Bone Metabolism: Promyelotic Leukemia Zinc Finger (PLZF) and Tumor Necrosis Factor-α-Stimulated Gene 6 (TSG-6) Identified by Gene Expression Analysis Play Roles in the Pathogenesis of Ossification of the Posterior Longitudinal Ligament

Journal of Pharmacological Sciences, 2006
.: To understand the molecular pathogenesis of ossification of the posterior longitudinal ligament of the spine (OPLL), an ectopic bone formation disease, we performed cDNA microarray analysis on cultured ligament cells from OPLL patients to understand ...
Ituro Inoue, Ryuji Ikeda, So Tsukahara
doaj   +1 more source

Anatomy and variation in the paraphyletic Mosasaurus lemonnieri assemblage from the Craie phosphatée de ciply, Belgium

The Anatomical Record, EarlyView.
Abstract Nineteenth century excavations of the Ciply‐Malogne Phosphatic Chalk Formation in Hainaut, Belgium, yielded over 50 partial mosasaur skeletons, the majority of which were referred to the species Mosasaurus lemonnieri Dollo, 1889. In the years since, this taxon has experienced a complicated taxonomic history, and its exceptional hypodigm has ...
Henry S. Sharpe, Hallie P. Street‐Sampson, Takuya Konishi, Michael W. Caldwell   +3 more
wiley   +1 more source

Clinical spectrum and importance of evaluation systems in degenerative cervical myeloradiculopathy

Indian Spine Journal, 2019
Degenerative cervical myelopathy includes facet joint arthropathy and/or intervertebral disc prolapse, as well as aberration (hypertrophy, calcification, or ossification) in the ligamentum flavum, and/or posterior longitudinal ligament.
Ganesh Swaminathan, Vetrivel Muralidharan, Baylis Vivek Joseph   +2 more
doaj   +1 more source

Histological description and bone compactness analysis of fossil (Aldabrachelys sp.) and extant Aldabra giant tortoise (Aldabrachelys gigantea) shell bone fragments

The Anatomical Record, EarlyView.
Abstract Aldabra Atoll, north of Madagascar and part of the Seychelles Outer Islands, is home to the Aldabra giant tortoise, Aldabrachelys gigantea, the only survivor of several species of giant tortoises that were once widespread on islands across the Western Indian Ocean.
Stefanie Herter, Nicole Klein, Massimo Delfino, Erik de Boer, Julian P. Hume, Jordan Bestwick, Frauke Fleischer‐Dogley, Annabelle Constance, Dennis M. Hansen, Torsten M. Scheyer   +9 more
wiley   +1 more source