Results 51 to 60 of about 8,909 (263)

Long‐Term Expandable Periosteal Organoids Reconstruct a Functional Regenerative Niche That Support Hematopoietic Stem Cell Maintenance and Bone Repair

Advanced Science, EarlyView.
A robust periosteal organoid system enables long‐term expansion while preserving native cellular heterogeneity. These organoids recapitulate functional niche environments, support hematopoietic stem cell maintenance, and attenuate aging‐associated decline ex vivo.
Jia Qing, Lanxin Gu, Lipeng Fu, Xin Gao, Zechuan Li, Hui Zhang, Wenpeng Song, Huixin Lv, Yongsheng Zhou, Ping Zhang   +9 more
wiley   +1 more source

Juvenile Ossifying Fibroma of the Mandible Managed With Transoral Resection and Mandibular Reconstruction Harvesting Rib Graft: A Case Series With Literature Review

International Journal of Medicine and Health Development
Juvenile ossifying fibromas constitute a group of heterogenous, rare, benign fibro-osseous lesions that affect the craniofacial skeleton including the jawbones.
Pradeep Muralidhar, M. Jithendar, Genoey George, Prajna P. Nayak, Shaikh Md. Abdul Feroz, Rashmi A. Saibannavar, Suresh J. Babu, C. Swarnalatha, Abhishek S. Nayyar   +8 more
doaj   +1 more source

Ossifying Fibroma in the Sinonasal Tract: A Rare Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2014
Ossifying fibroma involving the sinonasal tract is an extremely rare occurrence. We are reporting a case of ossifying fibroma in the left maxillary sinus in a 19-year-old female who presented with a mass in the left cheek and nasal obstruction.
Shekhar Charavarty, Debashish Datta, Esha Boro, Bijita Dutta   +3 more
doaj   +1 more source

Fuyuan Huoxue Decoction Promotes Lumbar Interbody Fusion in Rats: Role of Macrophage‐Driven Inflammation and the TLR9/NF‐κB Pathway

Advanced Science, EarlyView.
Fuyuan Huoxue decoction improves lumbar interbody fusion in rats while reducing inflammatory macrophage activity and supporting bone‐forming stem cells. Experiments implicate extracellular DNA and TLR9/NF‐κB signaling in early responses. These findings point to coordinated control of inflammation and osteogenesis as a potential route to stronger spinal
Hongwei Gao, Han Wu, Shaorong Li, Weijian Wang, Yijian Guo, Shuai Cheng, Jiayi Sun, Jilong An, Wei Zhang   +8 more
wiley   +1 more source

Juvenile ossifying fibroma of mandible

Dentistry and Medical Research, 2014
Ossifying fibroma is a benign, slow growing, and expansile lesion of the jaws. It is classified as one of the benign fibro-osseous lesions of the jaws. The juvenile ossifying fibroma (JOF) is commonly found in children and young adults.
K Srivastava Ram, Anand Kumar, Iqbal Ali, Puneet Wadhwani, Anurag Saxena, Mariyam Iqbal Ali   +5 more
doaj   +1 more source

PHGDH‐Mediated Serine Metabolism in Nucleus Pulposus Cells Is a Potential Therapeutic Target for Intervertebral Disc Degeneration

Advanced Science, EarlyView.
When nucleus pulposus cells senesce, PHGDH decreases, reducing serine synthesis and glutathione, impairing antioxidant capacity. The intermediate α‐KG also drops, lowering JMJD3 demethylase activity, increasing H3K27me3 at the Rap1b promoter, and reducing Rap1b expression, whose down‐regulation in turn activates mTORC1 and suppresses autophagy ...
Hao‐Wei Xu, Sheng‐Jie Chang, Xiao‐Wei Liu, Shu‐Bao Zhang, Ying‐Jie Wang, Shan‐Jin Wang   +5 more
wiley   +1 more source

A Rare Form of Microcephalic Primordial Dwarfism due to NSMCE2 Deficiency (Seckel Syndrome Type 10): A Report of Macular Involvement

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Biallelic variants in NSMCE2 (MMS21), which encodes the SUMO E3 ligase subunit of the SMC5/6 chromatin‐maintenance complex, have recently been implicated in microcephalic primordial dwarfism (MPD), corresponding to Seckel syndrome type 10 (OMIM #617246).
Cristina Peduto, Céline Huber, Clément Paya, Isabelle Audo, Nathalie Boddaert, Valérie Cormier‐Daire   +5 more
wiley   +1 more source

Central ossifying fibroma of mandible: A case report and review of literature

Journal of Indian Academy of Oral Medicine and Radiology, 2015
Ossifying fibroma (OF) is a benign, non-odontogenic tumor of the jaw, a type of fibro-osseous lesion. Traditionally, this type of lesion was subclassified histologically into ossifying fibroma and cementifying fibroma according to the hard tissues formed,
Anand N Swami, Lata M Kale, Sunil Surendraprasad Mishra, Sneha H Choudhary   +3 more
doaj   +1 more source

Peripheral ossifying fibroma

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2009
The peripheral ossifying fibroma (POF) is a reactive gingival overgrowth occurring frequently in the anterior maxilla in teenagers and young adults. The pediatric patient with a POF has special management considerations compared to the adult, as it requires early recognition and treatment by the dentist. It requires proper treatment protocol with close
Das U, Azher U
openaire   +3 more sources

Prenatal Presentation of RMRP‐Related Skeletal Dysplasia: Clinical and Genomic Expansion

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT The RNA subunit of the mitochondrial RNA processing endoribonuclease complex is encoded by RMRP. Biallelic variants in RMRP are known for anauxetic dysplasia 1 (AD), cartilage‐hair hypoplasia (CHH), and metaphyseal dysplasia without hypotrichosis.
Radhakrishnan Periyasamy, Pascal Joset, H. E. Veenstra‐Knol, Nicole Corsten‐Janssen, Tuula Rinne, Irene Valenzuela, Marta Codina‐Solà, Carlota Rodó, Marjolaine Willems, Constance Wells, Renaud Touraine, Maayke de Koning, Gijs Santen, Iris Hollink, André Travessa, Alessandro Mauro Spinelli, Paolo Peruzzo, Moneef Shoukier, Roland Axt‐Fliedner, Thomas Menter, Gwendolin Manegold‐Brauer, Isabel Filges   +21 more
wiley   +1 more source