Results 61 to 70 of about 9,010 (165)

Severe Hypercalcemia and Confusion in a Middle‐Aged Male: The Hidden Diagnosis of Parathyroid Carcinoma

Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.
Parathyroid cancer (PC) is one of the rarest causes of primary hyperparathyroidism (PHPT), typically exhibiting an indolent course but presenting with more severe symptoms compared to its benign counterparts. The diagnosis is most often made postoperatively through histopathological examination; however, certain clinical and biochemical features may ...
Helena Fahmi, Mahmoud Karaki, Fatima Yasmin, Layal Akl, Paola Atallah, Osamu Isozaki   +5 more
wiley   +1 more source

A patient with a history of breast cancer and multiple bone lesions: a case report

Journal of Medical Case Reports, 2017
Background Long-term severe hyperparathyroidism leads to thinning of cortical bone and cystic bone defects referred to as osteitis fibrosa cystica. Cysts filled with hemosiderin deposits may appear colored as “brown tumors.” Osteitis fibrosa cystica and ...
Marie-Angela Schnyder, Paul Stolzmann, Gerhard Frank Huber, Christoph Schmid   +3 more
doaj   +1 more source

Three Malagasy Cases of Severe Bone Complications Revealing Primary Hyperparathyroidism

Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.
Primary hyperparathyroidism (PHPT) is a metabolic disorder characterized by hypercalcemia with elevated or unsuppressed parathyroid hormone (PTH). It is rare in children but common in adults, particularly in women around the age of 50. In 85% of cases, PHPT is asymptomatic and is diagnosed following hypercalcemia and elevated PTH levels during routine ...
Zolalaina Andrianadison, Lalao Nomenjanahary Rakotonirina, Oliva Henintsoa Rakotonirainy, Mamonjisoa Olivier Andrianiaina, Mbola Narison Lala Rakotomahefa, Fahafahantsoa Rapelanoro Rabenja, Osamu Isozaki   +6 more
wiley   +1 more source

A rare case of “Brown tumor” of the axis with parathyroid adenoma and tertiary hyperparathyroidism

Journal of Craniovertebral Junction and Spine, 2023
“Brown tumors (BTs)” of the spine are benign rare lesions, seen in about 5%–13% of all patients with chronic hyperparathyroidism (HPT). They are not true neoplasms and are also known as osteitis fibrosa cystica or occasionally osteoclastoma. Radiological
Umesh Srikantha, Akshay Hari, Yadhu K Lokanath, D M Mahesh   +3 more
doaj   +1 more source

A Perfect Storm in Mineral Handling

Case Reports in Nephrology, Volume 2026, Issue 1, 2026.
Introduction One of the commonest complications of end‐stage renal disease (ESRD) is the disruption of normal mineral trafficking, with a major perturbation in the handling of calcium and phosphate. Background Here, we report a patient who presented some time ago along with his imaging, with some of the worst sequelae of these issues.
Wael L. Jebur, Stephen G. Holt, Poorani Gurumallesh Prabu   +2 more
wiley   +1 more source

A rare occurrence of primary hyperparathyroidism with brown tumor in the left maxilla

Gülhane Tıp Dergisi
Brown tumors are rare skeletal manifestations of hyperparathyroidism. It is a form of osteitis fibrosa cystica caused by hyperparathyroidism due to excessive secretion of parathyroid hormone. Then, hypercalcemia results in excessive osteoclastic activity
Muhammad Afiq Muhammed Fahimy, Siti Rahmah Hashim Isa Merican, Maya Mazuwin Yahya, Muhamamad Faeid Othman   +3 more
doaj   +1 more source

Brown Tumor of the Cervical Spines: A Case Report with Literature Review [PDF]

Asian Spine Journal, 2015
To report a rare case of axis brown tumor and to review literature of cervical spine brown tumor. Brown tumor is a rare bone lesion, incidence less than 5% in primary hyperparathyroidism.
Mohammad Dursi Alfawareh, Mohammed Mohamoud Halawani, Walid Ismail Attia, Khaled Naser Almusrea   +3 more
doaj   +1 more source

Biochemical Predictors and Clinical Characteristics for the Development of Cytopenia and Bone Marrow Involvement Among Patients With Primary Hyperparathyroidism

International Journal of Endocrinology, Volume 2026, Issue 1, 2026.
Background The clinical features associated with primary hyperparathyroidism (PHPT) giving rise to bone marrow fibrosis are poorly documented. We hypothesised that the severity of PHPT may contribute to the development of this complication. Methods We identified two clinical cases managed within our clinical service and reviewed case reports and cohort
Omer Abdelfadiel, Mohamed Abdalla, Ian Louis Ross, Sreeja Dattachoudhury   +3 more
wiley   +1 more source

Brown Tumors Mimicking Skeletal Metastases: A Diagnostic Pitfall in Primary Hyperparathyroidism

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Brown tumors are rare but important manifestations of primary hyperparathyroidism (PHPT). These benign, fibrotic, and erosive bony lesions result from localized rapid osteoclastic activity driven by excessive parathyroid hormone levels. Although brown tumors are considered one of the most pathognomonic signs of PHPT, they are infrequently ...
Uzma Akbar, Osama Ahmad, Fatima Sajjad, Khawar Saeed, Umer Dawar, Muhammad Salman Shah, Abdullah Afridi, Kamil Ahmad Kamil   +7 more
wiley   +1 more source

A Lost Opportunity: Early Nephrolithiasis as a Missed Indicator of Primary Hyperparathyroidism Over Eight Years

Clinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT Primary hyperparathyroidism may present with a diagnostic challenge due to its nonspecific initial symptoms, often delaying diagnosis. Nephrolithiasis, a common presentation, is often treated in isolation without consideration of an underlying hyperparathyroidism.
Prince Yaw Boahene, Solomon Gyabaah, Seth Kyei‐Fram, Paulinus Domeh, Afia Serwaa Bonsu, Bernard C. Nkum   +5 more
wiley   +1 more source