Results 181 to 190 of about 708,008 (375)

Daily Walking and the Risk of Incident Functional Limitation in Knee Osteoarthritis: An Observational Study

, 2014
Daniel K. White, Catrine Tudor‐Locke, Yuqing Zhang, Roger A. Fielding, Michael P. LaValley, David T. Felson, K. Douglas Gross, Michael C. Nevitt, Cora E. Lewis, James C. Torner, Tuhina Neogi   +10 more
openalex   +2 more sources

β2-Adrenoceptor Deficiency Results in Increased Calcified Cartilage Thickness and Subchondral Bone Remodeling in Murine Experimental Osteoarthritis

, 2022
Gundula Rösch, Dominique Muschter, Shahed Taheri, Karima El Bagdadi, Christoph Dorn, Andrea Meurer, Frank Zaucke, Arndt F. Schilling, Susanne Grässel, Rainer H. Straub, Zsuzsa Jenei‐Lanzl   +10 more
openalex   +1 more source

Patient-specific risk profile associated with early-onset primary osteoarthritis of the shoulder: is it really primary? [PDF]

, 2021
Fabian Plachel, Doruk Akgün, Jan-Philipp Imiolczyk, Marvin Minkus, Philipp Moroder   +4 more
openalex   +1 more source

FSTL1 Orchestrates Metabolic‐Epigenetic Crosstalk: Glycolysis‐Dependent H3K18 Lactylation Drives Cartilage Fibrosis in Osteoarthritis

Advanced Science, EarlyView.
FSTL1 promotes glycolysis during chondrocyte fibrosis by triggering the HIF‐1 signaling pathway, which causes lactate to accumulate. The buildup of lactate leads to changes in histone lysine lactylation, which in turn enhances the expression of genes associated with fibrosis.
Feng Lu, Yunyuan Yu, Guangrong Yin, Huiqun Hu, Shishuo Li, Yuting Tang, Yimin Liu, Maoyuan Li, Liang liang Wang, Chao Xu, Gongyin Zhao, Baojun Zhou, Yuji Wang   +12 more
wiley   +1 more source

Neuromodulation as a Potential Disease-Modifying Therapy for Osteoarthritis

, 2022
Carlos J. Cruz, L. Savannah Dewberry, Kevin J. Otto, Kyle D. Allen   +3 more
openalex   +2 more sources

Editorial: Inflammation and Biomarkers in Osteoarthritis [PDF]

, 2021
Ali Mobasheri, João Eurico Fonseca, Oreste Gualillo, Yves Henrotin, Raquel Largo, Gabriel Herrero‐Beaumont, Francisco Airton Castro Rocha   +6 more
openalex   +1 more source

Multi‐Omics Reveal the Dysregulated Gut‐Joint Axis in Knee Synovitis: Data from Two Osteoarthritis Studies in China

Advanced Science, EarlyView.
The “gut‐joint axis” in knee synovitis is uncovered. Integrated multi‐omics studies are conducted in two independent osteoarthritis cohorts. Synovitis is characterized an increased F/B ratio, as well as alterations of 3‐HIA, geranic acid, and TWEAK. Upregulated TWEAK receptor is found in high‐grade synovitis, and inversely correlated with lower TWEAK ...
Xiaoshuai Wang, Yi Liu, Ziying Sun, Jia Li, Zhihao Lu, Jiayuan Huang, Shixian Hu, Peihua Cao, Xiaolong Cao, Shangru Li, Jianzhao Ruan, Jinhui Liu, Jingyu Xie, Haitao Sun, Tianyu Chen, Shengfa Li, Zhaohua Zhu, Zhibo Wen, Rocky S. Tuan, David John Hunter, Zhong Alan Li, Dongquan Shi, Changhai Ding   +22 more
wiley   +1 more source

A Lightweight Browser-Based Tool for Collaborative and Blinded Image Analysis

Journal of Imaging
Collaborative manual image analysis by multiple experts in different locations is an essential workflow in biomedical science. However, sharing the images and writing down results by hand or merging results from separate spreadsheets can be error-prone ...
Philipp Schippers, Gundula Rösch, Rebecca Sohn, Matthias Holzapfel, Marius Junker, Anna E. Rapp, Zsuzsa Jenei-Lanzl, Philipp Drees, Frank Zaucke, Andrea Meurer   +9 more
doaj   +1 more source

LOXL2 in anabolic response to chondrodysplasia mice progressive TMJ and knee osteoarthritis [PDF]

, 2019
Osteoarthritis (OA) is a degenerative joint disease that affects an estimated 9.6 % of men and 18 % of women over 60 years of age. However, there is no chondroprotective agent that is approved for clinical application.
Alsaqer, Saqer
core  

The gut microbiome-joint connection: implications in osteoarthritis

, 2019
Lacey J. Favazzo, Honey Hendesi, David A. Villani, Sarah Soniwala, Qurratul-Ain Dar, Eric M. Schott, Steven R. Gill, Michael J. Zuscik   +7 more
openalex   +1 more source