Human Fibroblast‐Myeloid cell tissue atlas across lung, synovium, skin and heart
Background The availability of single‐cell RNA sequencing (scRNAseq data) in different tissues and disease states provides an opportunity to compare cellular subsets and identify common and unique cellular activation. In this study, we aimed to characterize shared and tissue‐specific myeloid and stromal phenotypes and to uncover key cellular subtypes ...
Lucy MacDonald +9 more
wiley +1 more source
Behavioral assessment of blue-fronted Amazon parrots (<i>Amazona aestiva</i> Linnaeus, 1758) subjected to experimentally induced osteoarthritis and rescue analgesia with tramadol in a laboratory environment. [PDF]
Xavier IM +5 more
europepmc +1 more source
Optimization of Arthroscopic All‐Inside Meniscus Repair With a Probe
Abstract Meniscal preservation is essential for knee function and long‐term joint health. All‐inside meniscus repair achieves outcomes comparable to the inside‐out technique, but technical challenges remain, including limited working space, suture cut‐out in degenerative tissue, unfavorable suture angles, and risk of cartilage injury or arthroscope ...
Hui‐Shan Angela Lim +1 more
wiley +1 more source
Global burden-integrated analysis of osteoarthritis research-to-translation dynamics, 1999-2023. [PDF]
Mukherjee R, Chang CM.
europepmc +1 more source
Abstract Osteochondral lesions of the knee, particularly in patients with early osteoarthritic changes, remain a clinical challenge. The Agili‐C implant (CartiHeal, Smith & Nephew), an aragonite‐based osteochondral scaffold, offers a single‐stage, off‐the‐shelf solution designed to regenerate both cartilage and subchondral bone.
Eric Wang +4 more
wiley +1 more source
Characterizing symptom burden in knee osteoarthritis: the predominant role of Kellgren-Lawrence grade 4 in functional decline and pain severity. [PDF]
Bozgeyik-Bagdatli S +3 more
europepmc +1 more source
Abstract Early meniscal repair and anatomic reconstruction in a multiligament knee injury optimizes outcomes and restores tibiofemoral mechanics. This technique describes a lateral meniscus posterior root and radial tear repair, with concomitant medial ramp repair, performed during single‐stage reconstruction of the anterior cruciate ligament ...
Romir Patel +6 more
wiley +1 more source
Evaluating the Effect of Electroacupuncture in Knee Osteoarthritis: Protocol for a Multicenter Randomized Controlled Trial [Letter]. [PDF]
Chen R, Zhang B, Li X.
europepmc +1 more source
Optimizing Anatomic Reduction of Vertical Meniscus Tears With All‐Inside Meniscus Repair
Abstract The lateral and medial meniscus play vital roles in load distribution across the knee joint and in the prevention of knee osteoarthritis. As such, every effort should be made to save and repair the meniscus when possible, as partial and total meniscectomies have been shown to impair the meniscus’ ability to effectively dissipate shock ...
Sophia Mavrommatis +4 more
wiley +1 more source
Abstract Multiligamentous knee injuries involving anterior cruciate ligament rupture and lateral‐sided instability, including proximal tibiofibular joint instability and lateral collateral ligament deficiency, present unique challenges in restoring knee stability.
Ryan J. Froom +4 more
wiley +1 more source

