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Osteoarthritis

Home Healthcare Now, 2023
The clinical appearance and radiological pattern of osteoarthritis have been identified in the skeletons of dinosaurs some 50-70 million years old, and in Egyptian mummies, and in ancient skeletons in England. Osteoarthritis patterns of joint involvement, often referred to as primary osteoarthritis, can be seen in the hands, spinal facet joints, hips ...
Deborah, Hale, Katherine, Marshall
openaire   +4 more sources

Inflammation in osteoarthritis: the latest progress and ongoing challenges

Current Opinion in Rheumatology, 2022
Purpose of review The understanding of inflammation in osteoarthritis is rapidly evolving. This review highlights important basic science, mechanistic, and clinical findings since 2020 that underscore the current notion of osteoarthritis as an ...
Alexander J. Knights   +2 more
semanticscholar   +1 more source

Osteoarthritis

Best Practice & Research Clinical Rheumatology, 2010
Internationally, prevalence estimates for osteoarthritis show wide variability depending on the age and sex of the studied population, the method of case identification used, and the specificity of joint sites included. Currently, there is no generally agreed "gold standard" for identifying cases of osteoarthritis in epidemiologic studies. Despite this
Busija, Lucy   +6 more
openaire   +3 more sources

Osteoarthritis

Best Practice & Research Clinical Rheumatology, 2008
Osteoarthritis (OA) is a chronic degenerative disorder characterized by cartilage loss. Its prevalence is high, and it is a major cause of disability. The cause of OA is not known; however, current evidence indicates that it is multifactorial. Major risk factors for osteoarthritis are age, female sex, obesity, geographic factors, occupational knee ...
Siddharth Kumar, Das, Abid, Farooqi
openaire   +2 more sources

Osteoarthritis

Science of Aging Knowledge Environment, 2004
In this case study, we describe the symptoms, evaluation, and management of a woman with osteoarthritis (OA). OA is the most common form of arthritis worldwide and it is a major cause of disability in the elderly. Although there are several aging-related changes in the musculoskeletal system that may contribute to the pathogenesis of this disease ...
Najia, Shakoor, Richard F, Loeser
openaire   +4 more sources

Osteoarthritis

The Lancet, 2019
Osteoarthritis is a leading cause of disability and source of societal cost in older adults. With an ageing and increasingly obese population, this syndrome is becoming even more prevalent than in previous decades. In recent years, we have gained important insights into the cause and pathogenesis of pain in osteoarthritis.
Hunter, DJ, Bierma - Zeinstra, Sita
openaire   +2 more sources

Osteoarthritis

The Lancet, 2015
Osteoarthritis is a major source of pain, disability, and socioeconomic cost worldwide. The epidemiology of the disorder is complex and multifactorial, with genetic, biological, and biomechanical components. Aetiological factors are also joint specific.
Glyn-Jones, S   +6 more
openaire   +7 more sources

Osteoarthritis

Rheumatic Disease Clinics of North America, 2011
The pathogenesis of osteoarthritis (OA) appears to be the result of a complex interplay between mechanical, cellular and biochemical forces. Obesity is the strongest risk factor for disease onset in the knee, and mechanical factors dominate the risk for disease progression. OA is a highly prevalent and disabling disease.
openaire   +2 more sources

Pain in Osteoarthritis

Veterinary Clinics of North America: Equine Practice, 2010
This article focuses on pain associated with osteoarthritis (OA). It first describes the basic biology of articular cartilage and other joint structures and the defining features of the osteoarthritic disease process. Subsequently, the possible origins of pain in OA are discussed before embarking on how to manage this clinical entity.
van Weeren, P.R., de Grauw, J.C.
openaire   +3 more sources

Osteoarthritis in the hand

The Journal of Hand Surgery, 1983
Patients who have disabling osteoarthritis of the hand are frequently given the wrong diagnosis, poor professional advice and inadequate treatment programmes. The exact cause of primary osteoarthritis remains unknown; however, an interplay of genetic factors, mechanical factors and biomechanical alterations in cartilage seems to be important.
A B, Swanson, G D, Swanson
openaire   +3 more sources

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