Results 201 to 210 of about 79,934 (285)

Correction: Triple-gene deletion for osteocalcin significantly impairs the alignment of hydroxyapatite crystals and collagen in mice. [PDF]

open access: yesFront Physiol
Xu Z   +12 more
europepmc   +1 more source

Valproic Acid Inhibits Ferroptosis and Improves Bone Integration in OVX Rats Through the AMPK/SIRT1 Pathway

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 8, August 2026.
ABSTRACT The prevalence of postmenopausal osteoporosis (PMOP) has been steadily increasing. Ferroptosis has been recognized as a critical factor influencing the bone‐forming ability of bone marrow mesenchymal stem cells (BMSCs). Valproic acid (VPA), an HDAC inhibitor, has been suggested to play a role in regulating osteoporosis development; however ...
Qing‐Song Gu   +8 more
wiley   +1 more source

Combined Effects of Puerarin and Adipose‐Derived Stem Cells on Alveolar Bone Preservation and Inflammation Control in Periodontitis Through p38MAPK Modulation

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 8, August 2026.
ABSTRACT This study evaluated the effects of puerarin and adipose‐derived stem cells (ADSCs), alone or combined, on p38MAPK activity, alveolar bone preservation, and inflammatory responses in a rat periodontitis (PD) model and in vitro. ADSCs were exposed to various puerarin concentrations to assess cell proliferation, osteogenic differentiation, and ...
Ting Yang, Xu Zhang, Liang‐Fu Zhang
wiley   +1 more source

Silk Fibroin‐Modified Titanium Implants for Bone Tissue Engineering: Structural Basis, Functionalization and Composite Strategies

open access: yesMacromolecular Bioscience, Volume 26, Issue 8, August 2026.
Silk fibroin coatings transform inert 3D‐printed porous titanium scaffolds into intelligent, bioactive implants. Leveraging its pH‐responsive structure and tunable degradation, silk fibroin enables spatiotemporal drug delivery, promotes osteoblast activity, and modulates macrophage immunity.
Jiajun Liu   +15 more
wiley   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang   +9 more
wiley   +1 more source

Effects of Menaquinone-7 on Bone Turnover Markers, Femoral Mechanical Resistance, and Histology in Young Ovariectomized Rats. [PDF]

open access: yesNutrients
Jecan A   +11 more
europepmc   +1 more source

Utilization of Des‐Gamma‐Carboxy‐Prothrombin in Estimating Vitamin K Status in People With Cystic Fibrosis: A Single Center Retrospective Review

open access: yesPediatric Pulmonology, Volume 61, Issue 8, August 2026.
ABSTRACT Background People with cystic fibrosis (CF) are at increased risk of fat‐soluble vitamin (A, D, E, and K) deficiencies secondary to exocrine pancreatic insufficiency (EPI). Estimation of vitamin K deficiency in routine clinical practice is challenging, and no uniform consensus exists due to lack of an accurate clinical test for the evaluation ...
Senthilkumar Sankararaman   +7 more
wiley   +1 more source

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