Results 101 to 110 of about 7,611 (212)

Sustained Hypoxia‐Inducible Factor 1‐Alpha Accumulation Disrupts the Articular Niche to Promote Osteoarthritis Pathogenesis

Aging Cell, Volume 25, Issue 7, July 2026.
Sustained HIF‐1α accumulation is not a compensatory shield, but a potent pathogenic driver of osteoarthritis. Continuous HIF‐1α signaling physically eradicates the avascular cartilage niche and primes the synovium for inflammation, establishing HIF‐1α as a critical target for disease‐modifying therapies.
Weiyuan Gong, Chu Tao, Xingyun Wang, Rongdong Liao, Jianglong Li, Xiongtian Guo, Minghao Qu, Jianmei Huang, Mingjue Chen, Fuxin Wei, Peng Wang, Lijun Lin, Di Chen, Qing Yao, Chunyi Wen, Guozhi Xiao   +15 more
wiley   +1 more source

Permanent tracheostomy meets 3D‐printing: Surgical technique and innovation

Equine Veterinary Education, Volume 38, Issue 7, Page 348-351, July 2026.
Summary This clinical commentary serves to accompany the recent case report from Debald et al. (2025) detailing the use of a removable, custom, 3D‐printed implant to manage a dynamically collapsing, permanent tracheal stoma. This creative use of an increasingly common technology provided a cost‐effective manner to successfully manage the complications ...
D. Major
wiley   +1 more source

[Osteochondral lesions of the talus in adolescents].

Acta orthopaedica et traumatologica turcica, 2004
Osteochondral lesions of the talus range from those confined to the hyaline cartilage covering the articular surface to those involving the subchondral bone. The lesion may not be apparent on the surface of the cartilage or it may be confined to the subchondral bone without cartilage involvement.
OZENCİ, A., AYDİN, Ahmet
openaire   +2 more sources

Subchondral and Osteochondral Unit Bone Damage in the Fetlock Region of Sport Horses Using Low-Field MRI: Case Series

Animals
Damage to the osteochondral unit is a common cause of lameness in horses. Published descriptions of MRI findings of osteochondral unit and subchondral damage are currently lacking, and only a few reports describe outcomes in sport horses.
Donatella De Zani, Vanessa Rabbogliatti, Silvia Rabba, Luigi Auletta, Maurizio Longo, Davide D. Zani   +5 more
doaj   +1 more source

Lateromedial and oblique radiographs detect most fetlock pathologies as effectively as a full series in horses

Equine Veterinary Journal, Volume 58, Issue 4, Page 934-945, July 2026.
Abstract Background Radiographic protocols for the metacarpo‐/tarsophalangeal joint during pre‐purchase examinations (PPE) vary internationally, but their impact on pathology detection remains unclear. Optimising imaging protocols is essential to balance diagnostic accuracy with workflow efficiency and radiation exposure.
A. Northwood, D. Berner
wiley   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Osteochondral lesion of the talus: still a problem? [PDF]

EFORT Open Rev, 2022
Krause F, Anwander H.
europepmc   +1 more source

Nanozymes at the Bio‐Nano Interface: From Synthesis, Defect Engineering, Catalytic Behavior in Biological Microenvironments, and Biosafety Implications

Advanced Materials Interfaces, Volume 13, Issue 11, 9 June 2026.
Nanozymes (NZs) have emerged as versatile artificial enzymes with tunable catalytic properties driven by atomic coordination, defect engineering, and surface chemistry. This review presents a bio–nano interface framework linking synthesis strategies, structural design, and catalytic behavior within complex biological microenvironments.
Karen Guadalupe Quintero‐Garrido, Aída Jimena Velarde‐Salcedo, Alejandro López‐Amador, Noé Arjona, Citlali Uitz Toalá, Carmen Gonzalez, Beatriz Liliana España‐Sánchez   +6 more
wiley   +1 more source

Primary Modified Broström Procedure Shows Superior Outcome to Revision to Lateral Ankle Ligament Reconstruction in Patients With Chronic Lateral Ankle Instability at 5‐Year Follow‐Up

Arthroscopy, Volume 42, Issue 6, Page 1041-1049, June 2026.
Purpose To compare the mid‐term clinical and radiological outcomes of primary modified Broström procedure (MBP) and revision to lateral ankle ligament reconstruction (LALR) in patients with chronic lateral ankle instability. Methods We retrospectively reviewed all the patients who underwent primary MBP or revision to LALR between November 2005 and ...
Jin Woo Lee, Kwang Hwan Park, Tae Hyun Kim, Yeo Kwon Yoon, Seung Hwan Han, Dong Woo Shim   +5 more
wiley   +1 more source

Next‐Generation Surgery: Integrating Artificial Intelligence, Genetic Technologies, Bioengineering and Rehabilitation Into Modern Practices

Exploration, Volume 6, Issue 3, June 2026.
This graphic abstract depicts the convergence of artificial intelligence, genetic technologies, bioengineering, and rehabilitation as the core pillars of next‐generation surgery. These domains collectively enhance preoperative planning, intraoperative precision, tissue reconstruction, and postoperative recovery, driving a paradigm shift toward ...
Dengxiong Li, Jie Wang, Zhipeng Wang, Ruicheng Wu, Zhouting Tuo, Fanglin Shao, Wenjing Ge, Ziyu Shu, Yubo Yang, Dilinaer Wusiman, Qingxin Yu, Luxia Ye, Alisha Pati‐Alam, Facai Zhang, Koo Han Yoo, Susan Heavey, William C. Cho, Dechao Feng   +17 more
wiley   +1 more source