Results 71 to 80 of about 7,611 (212)

Functional implications of lesion morphology in untreated osteochondral lesions of the talus

Journal of Orthopaedic Surgery and Research
Background Osteochondral lesions of the talus (OLTs) are a significant cause of chronic ankle pain and functional impairment. However, the relationship between lesion morphology and functional scores remains insufficiently studied, particularly in ...
Mehmet Orçun Akkurt, Ali Said Nazlıgül, Nihat Yiğit, Sadık Emre Erginoğlu, Nuri Koray Ülgen   +4 more
doaj   +1 more source

CD8+ T‐cells, CD86+ macrophages and TNF‐α signalling pathways are correlated with fetlock osteoarthritis in racehorses

Equine Veterinary Journal, EarlyView.
Abstract Background There is emerging evidence for the role of the immune system in osteoarthritis (OA) pathophysiology; however, little is known about how immune cells and the synovial transcriptome are altered in naturally occurring equine OA. Objectives To evaluate synovial fluid (SF) and synovial membrane (SM) immune cell populations and the SM ...
E. J. Secor, E. N. Chow, M. Thomas, L. Johnson, A. Siefert, B. Wagner, J. B. Engiles, H. L. Reesink   +7 more
wiley   +1 more source

The Stromal Vascular Fraction From Fat Tissue in the Treatment of Osteochondral Knee Defect: Case Report

Frontiers in Medicine, 2018
In this study we applied autologous fat tissue stromal vascular fraction (SVF) cells in combination with microfracturing technique in a 36-year-old man with an osteochondral lesion of the medial femoral condyle 8 months after the injury.
Ramil Z. Salikhov, Ramil Z. Salikhov, Ruslan F. Masgutov, Ruslan F. Masgutov, Mikhail A. Chekunov, Leysan G. Tazetdinova, Galina Masgutova, Oleg V. Teplov, Damir Galimov, Damir Galimov, Yuri Plakseichuk, Ramil Yagudin, Igor O. Pankov, Albert Rizvanov, Albert Rizvanov   +14 more
doaj   +1 more source

Matching TGF‐β1 Activation With Stress‐Responsive Charge‐Reversal Hydrogel Microspheres for the Treatment of Osteoarthritis

Exploration, EarlyView.
Based on the interaction between the weakly cross‐linked disulfide bonds that break under stress and charge‐reversal messenger molecules, we herein achieved nanoparticle charge reversal under stress and constructed a stress‐responsive charge‐reversal hydrogel microsphere system using microfluidic technology.
Feng Lin, Yiwen Xu, Lei Xiang, Yueliang Zhu, Yihan Li, Yaping Zhuang, Zengjie Zhang, Jiayu Chen, Heemin Kang, Ning Zhang, Xiaohua Yu, Wenguo Cui   +11 more
wiley   +1 more source

Osteochondral Lesions of Major Joints

The Eurasian Journal of Medicine, 2019
Abstract This paper provides information about osteochondral lesions (OCL) and example cases of OCL occurring in major joints, some of which are rarely seen. This simple tutorial is presented in question and answer format.
Durur-Karakaya, Afak, Durur-Subasi, Irmak, YILDIRIM, Ömer Selim   +2 more
openaire   +3 more sources

Holistic bone developing microenvironment engineered apoptotic extracellular vesicles recapitulate multidimensional developmental signatures in adult and senile bone repair

Interdisciplinary Medicine, EarlyView.
The developing bone was identified as an M2a‐like macrophage driven immune microenvironment with multidimensional developmental signatures. hME‐ApoEVs were successfully fabricated via stimulating the M2a‐like developing microenvironment in vitro and confirmed its recapitulation of developmental features.
Xiaoran Yu, Jieyun Xu, Yuan Zhao, Xinyu Guo, Hongcheng Chen, Junlong Xue, Yong Ao, Linjun Zhang, Xiaomeng Gao, Xueli Mao, Songtao Shi, Zetao Chen   +11 more
wiley   +1 more source

Minimally Invasive Management of Posterolateral Osteochondral Lesions of the Talus Using Posterior Ankle Arthroscopy and Autologous Iliac Osteochondral Grafts

Arthroscopy Techniques
Chronic osteochondral lesions of the talus often require bone grafts to support healing. When located posterolaterally, these lesions require an open lateral malleolar osteotomy for adequate exposure.
Parthiban Sivasamy, M.D., Taihei Miura, M.D., Ph.D., Yasuyuki Jujo, M.D., Ph.D., Masato Takao, M.D., Ph.D.   +3 more
doaj   +1 more source

Mapping Fatty Acid Composition in the Human Knee: Short‐Term Repeatability at 3T

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Alterations in periarticular lipid composition are implicated in musculoskeletal diseases, yet short‐term reliability of MRI‐based triglyceride composition mapping in the knee is not fully established. Purpose To evaluate 1‐week repeatability of proton‐density fat fraction (PDFF) and triglyceride fatty‐acid composition—saturated ...
Dimitri Martel, Anne Adlung, Baptiste Busi, Rollanda Bernadin, Yagni Shah, Thorsten Kirsch, Richard Kijowski, Guillaume Madelin, Amparo Ruiz   +8 more
wiley   +1 more source

Surgical caseload and annual volume influence cartilage treatment strategies in primary anterior cruciate ligament reconstruction

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate how surgeon and clinic volume, along with patient‐, injury‐ and surgery‐related factors, influence cartilage injury management in primary anterior cruciate ligament reconstruction (ACLR). Methods This retrospective cohort study analysed cartilage treatment (debridement, microfracture, other methods or left in situ) in ...
Dzan Rizvanovic, Markus Waldén, Magnus Forssblad, Anders Stålman   +3 more
wiley   +1 more source

Microfracture for full‐thickness chondral lesions of the knee in elite athletes leads to high return‐to‐play rates

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Injuries to the knee are common in elite athletes and often involve damage to the articular cartilage. Given the high demands of elite sport, full‐thickness articular cartilage defects in the knee can be career‐limiting or threatening.
David J. Haslhofer, Jobe Shatrov, Mary Jones, Wahid Abdul, Arman Motesharei, Simon V. Ball, Andy Williams   +6 more
wiley   +1 more source