Results 41 to 50 of about 36,128 (242)

Effects of a high‐fat diet on gut microbiota and possible implications for bone health in male Wistar rats

open access: yesLipids, EarlyView.
Abstract Diet plays an important role in the composition of gut microbiota. Emerging research suggests that bone homeostasis can also be influenced by the gut microbiota. The aim of this study was to assess possible alterations in gut microbiota in an experimental obesity model induced by a high‐fat diet (HFD) and the possible effects on parameters of ...
Fernanda Guedes Rodrigues   +6 more
wiley   +1 more source

Osteocytes as a record of bone formation dynamics: A mathematical model of osteocyte generation in bone matrix [PDF]

open access: yes, 2014
The formation of new bone involves both the deposition of bone matrix, and the formation of a network of cells embedded within the bone matrix, called osteocytes.
Buenzli, Pascal R
core   +3 more sources

Recent Advances in Injectable Hydrogel Biotherapeutics for Regenerative Dental Medicine

open access: yesMacromolecular Bioscience, EarlyView.
This review analyses multifunctional injectable hydrogels, natural or synthetic, physically or chemically crosslinked, that deliver exosomes, stem cells, and other bioactive cues to inflamed or damaged oral tissues. We discuss their immunomodulatory, antimicrobial, angiogenic, and osteogenic capacities, highlighting advances that enable regenerative ...
Renan Dal‐Fabbro   +6 more
wiley   +1 more source

Short-term Osteoclastic Activity Induced by Locally High Concentrations of Recombinant Human Bone Morphogenetic Protein–2 in a Cancellous Bone Environment [PDF]

open access: yes, 2009
Study Design. An experimental study investigating osteoclastic activity induced by rhBMP-2 in sheep. Objective. To examine the effects of increasing local rhBMP-2 concentration on osteoclastic response and peri-implant bone resorption.
Badura, Jeffrey   +5 more
core   +1 more source

Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis

open access: yesMed Research, EarlyView.
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang   +7 more
wiley   +1 more source

The healing pattern of osteoid osteomas on computed tomography and magnetic resonance imaging after thermocoagulation [PDF]

open access: yes, 2007
Objective To compare the healing pattern of osteoid osteomas on computed tomography (CT) and magnetic resonance imaging (MRI) after successful and unsuccessful thermocoagulation.
Bloem, Johan L.   +5 more
core   +2 more sources

Medial femorotibial and femoropatellar articular cartilage delamination following intra‐articular therapy with triamcinolone and gentamicin in five yearlings

open access: yesEquine Veterinary Education, EarlyView.
Summary Subchondral lucencies (SCLs) of the medial femoral condyle (MFC) are a cause of lameness in young horses, potentially affecting future athletic performance. Due to the widespread use of pre‐sales screening radiographs for Thoroughbred weanlings and yearlings, these lesions are frequently identified at various stages of progression without the ...
C. P. Beggan   +2 more
wiley   +1 more source

Transient Local Bone Remodeling Effects of rhBMP-2 in an Ovine Interbody Spine Fusion Model [PDF]

open access: yes, 2016
Background: Recombinant human bone morphogenetic protein-2 (rhBMP-2) is a powerful osteoinductive morphogen capable of stimulating the migration of mesenchymal stem cells (MSCs) to the site of implantation and inducing the proliferation and ...
Badura, Jeffrey   +7 more
core   +1 more source

Pathology reporting of hepatoblastoma resections: recommendations from the international collaboration on cancer reporting

open access: yesHistopathology, EarlyView.
This is the first international dataset for the reporting of hepatoblastoma resection specimens produced by the International Collaboration on Cancer Reporting (ICCR). The aim is to standardize pathology reports, facilitating international data comparisons and improving management of hepatoblastoma on a global level.
Dolores H López‐Terrada   +13 more
wiley   +1 more source

Buccal Bone Wall Thickness Dictates the Extent of Vertical Buccal Bone Loss Following Implant Placement: A Preclinical Study

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To assess buccal vertical bone resorption following implant placement in healed sites with varying buccal bone wall thicknesses. Materials and Methods In 11 miniature pigs, three tapered hybrid titanium implants were placed per hemi‐maxilla in healed bone. Sites were randomised into three groups based on buccal bone wall thickness: G1 (< 1.
Jean‐Claude Imber   +6 more
wiley   +1 more source

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