Results 1 to 10 of about 32,063 (268)

Osteomalacia and Vitamin D Status: A Clinical Update 2020

open access: yesJBMR Plus, 2021
Historically, rickets and osteomalacia have been synonymous with vitamin D deficiency dating back to the 17th century. The term osteomalacia, which literally means soft bone, was traditionally applied to characteristic radiologically or histologically ...
Salvatore Minisola   +5 more
doaj   +2 more sources

Tumor-Induced Osteomalacia: A Systematic Clinical Review of 895 Cases

open access: yesCalcified Tissue International, 2022
Tumor-induced osteomalacia (TIO) is a rare and largely underdiagnosed paraneoplastic condition. Previous reviews often reported incomplete data on clinical aspects, diagnosis or prognosis. The aim of this study was to present a systematic clinical review
Ariadne Bosman
exaly   +2 more sources

Burosumab Improved Histomorphometric Measures of Osteomalacia in Adults with X-Linked Hypophosphatemia: A Phase 3, Single-Arm, International Trial

open access: yesJournal of Bone and Mineral Research, 2019
In adults with X‐linked hypophosphatemia (XLH), excess FGF23 impairs renal phosphate reabsorption and suppresses production of 1,25‐dihydroxyvitamin D, resulting in chronic hypophosphatemia and persistent osteomalacia.
Karl L Insogna   +2 more
exaly   +2 more sources

The Foot That Broke Both Hips: A Case Report and Literature Review of Tumor-Induced Osteomalacia

open access: yesCase Reports in Rheumatology, 2017
Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterized by hypophosphatemia and clinical symptoms of osteomalacia. Only discussed as case reports, there is still limited knowledge of this condition as a potentially curable cause ...
Sara Beygi   +2 more
doaj   +2 more sources

Nutritional Rickets and Osteomalacia in the Twenty-first Century: Revised Concepts, Public Health, and Prevention Strategies

open access: yesCurrent Osteoporosis Reports, 2017
Purpose of ReviewNutritional rickets and osteomalacia are common in dark-skinned and migrant populations. Their global incidence is rising due to changing population demographics, failing prevention policies and missing implementation strategies.
S. Uday, W. Högler
exaly   +2 more sources

Bone histomorphometry in the evaluation of osteomalacia

open access: yesBone Reports, 2018
With the widespread use of measurement of bone mineral density to detect, diagnose, and monitor therapy in the management of osteoporosis, bone histomorphometry has largely been relegated to research settings and academic pursuits.
Arti Bhan, Shijing Qiu, Sudhaker D. Rao
doaj   +2 more sources

Tumour-induced osteomalacia

open access: yesNature Reviews Disease Primers, 2017
Salvatore Minisola   +2 more
exaly   +3 more sources

Case Report: Phosphaturic mesenchymal tumor presenting solely as knee pain without hypophosphatemia [PDF]

open access: yesFrontiers in Oncology
Phosphaturic mesenchymal tumor (PMT) is a rare tumor disease that often leads to tumor-induced osteomalacia (TIO). The typical manifestations of this disease include hypophosphatemia and osteomalacia. The main symptom in most PMT patients is diffuse pain
Qianqian Cao, Cheng Cheng, Zhipeng Dai
doaj   +2 more sources

Follow-Up of Adefovir Dipivoxil Induced Osteomalacia: Clinical Characteristics and Genetic Predictors

open access: yesFrontiers in Pharmacology, 2021
Adefovir dipivoxil (ADV) is widely used for chronic hepatitis B therapy in China. To explore the clinical features and prognosis of ADV-induced osteomalacia and to analyze the association between osteomalacia and genetic variants in 51 drug transporters ...
Jiao Zhao   +5 more
doaj   +1 more source

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