Osteomalacia and Vitamin D Status: A Clinical Update 2020
JBMR Plus, 2021 Historically, rickets and osteomalacia have been synonymous with vitamin D deficiency dating back to the 17th century. The term osteomalacia, which literally means soft bone, was traditionally applied to characteristic radiologically or histologically ...
Salvatore Minisola +5 more
doaj +2 more sources
Bone histomorphometry in the evaluation of osteomalacia
Bone Reports, 2018 With the widespread use of measurement of bone mineral density to detect, diagnose, and monitor therapy in the management of osteoporosis, bone histomorphometry has largely been relegated to research settings and academic pursuits.
Arti Bhan, Shijing Qiu, Sudhaker D. Rao
doaj +2 more sources
The Foot That Broke Both Hips: A Case Report and Literature Review of Tumor-Induced Osteomalacia
Case Reports in Rheumatology, 2017 Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterized by hypophosphatemia and clinical symptoms of osteomalacia. Only discussed as case reports, there is still limited knowledge of this condition as a potentially curable cause ...
Sara Beygi +2 more
doaj +2 more sources
Osteomalacia Following Iron Infusion Therapy in a Patient With Rendu-Osler-Weber Syndrome: F-18-FDG PET/CT Discrimination of a Stress Fracture in the Setting of a Musculoskeletal Tumor Mimic. [PDF]
Clin Case RepABSTRACT This case report highlights a rare occurrence of osteomalacia induced by hypophosphatemia secondary to ferric carboxymaltose (FCM) therapy in a patient with hereditary hemorrhagic telangiectasia (HHT, or Rendu‐Osler‐Weber syndrome). A 21‐year‐old man presented with left tibial pain without prior trauma, accompanied by severe hypophosphatemia ...
Vasios IS +4 more
europepmc +2 more sources
Tumor-Induced Osteomalacia: A Systematic Clinical Review of 895 Cases
Calcified Tissue International, 2022 Tumor-induced osteomalacia (TIO) is a rare and largely underdiagnosed paraneoplastic condition. Previous reviews often reported incomplete data on clinical aspects, diagnosis or prognosis. The aim of this study was to present a systematic clinical review
A. Bosman +8 more
semanticscholar +1 more source
Osteomalacia in Adults: A Practical Insight for Clinicians
Journal of Clinical Medicine, 2023 The term osteomalacia (OM) refers to a series of processes characterized by altered mineralization of the skeleton, which can be caused by various disorders of mineral metabolism. OM can be genetically determined or occur due to acquired disorders, among
L. Arboleya +4 more
semanticscholar +1 more source
TUMOR-INDUCED OSTEOMALACIA: A COMPREHENSIVE REVIEW.
Endocrine reviews, 2022 Tumor-induced osteomalacia (TIO) is an ultrarare paraneoplastic syndrome due to overproduction of fibroblast growth factor 23 (FGF23), with profound effects on the morbidity of the patients affected.
S. Minisola +8 more
semanticscholar +1 more source
Global guidance for the recognition, diagnosis, and management of tumor‐induced osteomalacia
Journal of Internal Medicine, 2022 Tumor‐induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by mesenchymal tumors that secrete fibroblast growth factor 23 (FGF23). Patients present with progressive bone pain, muscle weakness, and fragility fractures.
S. M. Jan de Beur +14 more
semanticscholar +1 more source
Tumor induced osteomalacia: a systematic review and individual patient's data analysis.
Journal of Clinical Endocrinology and Metabolism, 2022 CONTEXT Tumor induced osteomalacia (TIO) is a rare paraneoplastic syndrome, usually caused by small, benign and slow-growing phosphaturic mesenchymal tumors.
D. Rendina +8 more
semanticscholar +1 more source
Osteomalacia as a Complication of Intravenous Iron Infusion: A Systematic Review of Case Reports
Journal of Bone and Mineral Research, 2022 Randomized control trials (RCTs) have shown that certain intravenous iron preparations can induce high levels of fibroblast growth factor 23 (FGF‐23) and persistent hypophosphatemia.
T. Vilaca +4 more
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