Results 11 to 20 of about 26,453 (213)

Osteomalacia and Vitamin D Status: A Clinical Update 2020

open access: yesJBMR Plus, 2021
Historically, rickets and osteomalacia have been synonymous with vitamin D deficiency dating back to the 17th century. The term osteomalacia, which literally means soft bone, was traditionally applied to characteristic radiologically or histologically ...
Salvatore Minisola   +5 more
doaj   +2 more sources

The Foot That Broke Both Hips: A Case Report and Literature Review of Tumor-Induced Osteomalacia

open access: yesCase Reports in Rheumatology, 2017
Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterized by hypophosphatemia and clinical symptoms of osteomalacia. Only discussed as case reports, there is still limited knowledge of this condition as a potentially curable cause ...
Sara Beygi   +2 more
doaj   +2 more sources

Bone histomorphometry in the evaluation of osteomalacia

open access: yesBone Reports, 2018
With the widespread use of measurement of bone mineral density to detect, diagnose, and monitor therapy in the management of osteoporosis, bone histomorphometry has largely been relegated to research settings and academic pursuits.
Arti Bhan, Shijing Qiu, Sudhaker D. Rao
doaj   +2 more sources

Follow-Up of Adefovir Dipivoxil Induced Osteomalacia: Clinical Characteristics and Genetic Predictors

open access: yesFrontiers in Pharmacology, 2021
Adefovir dipivoxil (ADV) is widely used for chronic hepatitis B therapy in China. To explore the clinical features and prognosis of ADV-induced osteomalacia and to analyze the association between osteomalacia and genetic variants in 51 drug transporters ...
Jiao Zhao   +5 more
doaj   +1 more source

Tumor-Induced Osteomalacia: A Systematic Clinical Review of 895 Cases

open access: yesCalcified Tissue International, 2022
Tumor-induced osteomalacia (TIO) is a rare and largely underdiagnosed paraneoplastic condition. Previous reviews often reported incomplete data on clinical aspects, diagnosis or prognosis. The aim of this study was to present a systematic clinical review
A. Bosman   +8 more
semanticscholar   +1 more source

TUMOR-INDUCED OSTEOMALACIA: A COMPREHENSIVE REVIEW.

open access: yesEndocrine reviews, 2022
Tumor-induced osteomalacia (TIO) is an ultrarare paraneoplastic syndrome due to overproduction of fibroblast growth factor 23 (FGF23), with profound effects on the morbidity of the patients affected.
S. Minisola   +8 more
semanticscholar   +1 more source

Global guidance for the recognition, diagnosis, and management of tumor‐induced osteomalacia

open access: yesJournal of Internal Medicine, 2022
Tumor‐induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by mesenchymal tumors that secrete fibroblast growth factor 23 (FGF23). Patients present with progressive bone pain, muscle weakness, and fragility fractures.
S. M. Jan de Beur   +14 more
semanticscholar   +1 more source

Tumor induced osteomalacia: a systematic review and individual patient's data analysis.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2022
CONTEXT Tumor induced osteomalacia (TIO) is a rare paraneoplastic syndrome, usually caused by small, benign and slow-growing phosphaturic mesenchymal tumors.
D. Rendina   +8 more
semanticscholar   +1 more source

Osteomalacia Is Not a Single Disease

open access: yesInternational Journal of Molecular Sciences, 2022
Among bone-material qualities, mineralization is pivotal in conferring stiffness and toughness to the bone. Osteomalacia, a disease ensuing from inadequate mineralization of the skeleton, is caused by different processes leading to decreased available ...
L. Cianferotti
semanticscholar   +1 more source

A Rare Case of Hypophosphataemic Osteomalacia in von Recklinghausen Neurofibromatosis

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2021
Background: Neurofibromatosis type 1 (NF1), also known as von Recklinghausen disease, is a one of the more common hereditary autosomal disorders. However, osteomalacia in neurofibromatosis type 1 is very rare tumour-induced osteomalacia; fibroblast ...
Yasmine Makhlouf   +6 more
doaj   +1 more source

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