Results 21 to 30 of about 43,529 (272)

Osteomalacia Is Not a Single Disease

International Journal of Molecular Sciences, 2022
Among bone-material qualities, mineralization is pivotal in conferring stiffness and toughness to the bone. Osteomalacia, a disease ensuing from inadequate mineralization of the skeleton, is caused by different processes leading to decreased available ...
L. Cianferotti
semanticscholar   +1 more source

Diagnosis and Management of Tumor-induced Osteomalacia: Perspectives From Clinical Experience

Journal of the Endocrine Society, 2021
Purpose Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome of abnormal phosphate and vitamin D metabolism caused by typically small endocrine tumors that secrete fibroblast growth factor 23 (FGF23).
K. Dahir, M. Zanchetta, I. Stanciu, C. Robinson, Janet Y. Lee, R. Dhaliwal, J. Charles, R. Civitelli, M. S. Roberts, S. Krolczyk, T. Weber   +10 more
semanticscholar   +1 more source

Challenges in the management of tumor-induced osteomalacia (TIO).

Bone, 2021
Tumor-induced osteomalacia (TIO), also known as oncogenic osteomalacia, is a rare acquired paraneoplastic disease that is challenging to diagnose and treat.
M. Brandi, G. Clunie, P. Houillier, S. M. Jan de Beur, S. Minisola, R. Oheim, L. Seefried   +6 more
semanticscholar   +1 more source

Diffuse and Prolonged Bone Pain Revealing Tumor‐Induced Osteomalacia: A Case Report [PDF]

Clin Case Rep
ABSTRACT Tumor‐induced osteomalacia should be considered in patients with unexplained bone pain and fractures. Advanced imaging, such as Ga68‐DOTATATE PET/CT, enables precise tumor localization, and surgical excision can rapidly normalize phosphate metabolism and resolve symptoms, underscoring the importance of early diagnosis and intervention.
Amraei R, Karimi A, Nazarpoor S, Choobkar S.   +3 more
europepmc   +2 more sources

Burosumab for the Treatment of Tumor‐Induced Osteomalacia

Journal of Bone and Mineral Research, 2020
Tumor‐induced osteomalacia (TIO) is caused by phosphaturic mesenchymal tumors producing fibroblast growth factor 23 (FGF23) and is characterized by impaired phosphate metabolism, skeletal health, and quality of life.
S. M. Jan de Beur, P. Miller, T. Weber, M. Peacock, K. Insogna, R. Kumar, F. Rauch, D. Luca, T. Cimms, M. S. Roberts, Javier San Martin, T. Carpenter   +11 more
semanticscholar   +1 more source

Epidemiology of Tumor-Induced Osteomalacia in Denmark

Calcified Tissue International, 2021
Tumor-induced osteomalacia (TIO) is a rare, acquired condition of phosphate wasting due to phosphaturic mesenchymal tumors. Because the incidence and prevalence of TIO is unknown, we conducted an observational cohort study using national Danish health ...
B. Abrahamsen, Christopher D. Smith, S. Minisola   +2 more
semanticscholar   +1 more source

Transport of apolipoproteins A-I and A-II by human thoracic duct lymph [PDF]

, 1981
The daily transport of human plasma apolipoproteins A-I and A-II, triglyceride, and total cholesterol from the thoracic duct lymph into plasma was measured in 2 subjects before and 3 subjects after renal transplantation. Lymph triglyceride transport was ~
Anderson, DW, Brewer, HB, Bronzert, TJ, Forte, T, Lindgren, FT, Niblack, GD, Schaefer, EJ, Starzl, TE, Zech, LA   +8 more
core   +1 more source

Clinical presentation and etiology of osteomalacia/rickets in adolescents

Saudi Journal of Kidney Diseases and Transplantation, 2013
This study was conducted to determine the causes and clinical presentations of osteomalacia/rickets in adolescents seen at the King Abdulaziz Medical City (KAMC), Riyadh.
Mohammad A Hazzazi, Ibrahim Alzeer, Waleed Tamimi, Mohsen Al Atawi, Ibrahim Al Alwan   +4 more
doaj   +1 more source

Oncogenic Osteomalacia: An Approach to Diagnosis with a Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2017
Oncogenic osteomalacia, also known as tumour induced osteomalacia, is a rare paraneoplastic syndrome caused by mesenchymal tumours secreting Fibroblast Growth Factor-23 (FGF-23).
Biswajit Dey, Debasis Gochhait, Hema Subramanian, Madhusudhanan Ponnusamy   +3 more
doaj   +1 more source

Ideology and disease identity : the politics of rickets, 1929-1982 [PDF]

, 2013
How can we assess the reciprocal impacts of politics and medicine in the contemporary period? Using the example of rickets in twentieth century Britain, I will explore the ways in which a preventable, curable non-infectious disease came to have enormous ...
Apple, Arneil, Arneil, Benson, Berry, Bivins, British Paediatric Association, Carne, Chick, Dunnigan, Dunnigan, Dunnigan, Dunnigan, Ford, Ford, Ford, Ford, Frazer, Games, Grant, Heath, Hodgkin, Holmes, Hutt, Jameson, Kamminga, Kamminga, Lester, M'Gonigle, MacNalty, Magee, Marrack, McIntosh, McKay, Murcott, Orwell, Roberta Bivins, Robertson, Schwarz, Smerdon, Smith, Stanbury, Stewart, Swan, Walker, Webster, Webster, Webster, Webster, Whistler, Young   +50 more
core   +1 more source