Results 31 to 40 of about 43,529 (272)

FGF23-related hypophosphatemic rickets/osteomalacia: diagnosis and new treatment.

Journal of Molecular Endocrinology, 2020
FGF23 is a phosphaturic hormone produced by bone. FGF23 reduces serum phosphate by suppressing proximal tubular phosphate reabsorption and intestinal phosphate absorption.
S. Fukumoto
semanticscholar   +1 more source

Osteoporosis and osteomalacia - clinical and diagnostic problems

Travmatologiâ i Ortopediâ Rossii, 2016
Aim: to define main clinical and diagnostical problems related to osteoporosis and osteomalacia. Literature data showed that not only osteoporosis but osteomalacia may be the reason for decreasing of mechanical properties of skeleton with risk of low ...
A. S. Avrunin
doaj   +1 more source

Interim Analysis of a Phase 2 Open‐Label Trial Assessing Burosumab Efficacy and Safety in Patients With Tumor‐Induced Osteomalacia

Journal of Bone and Mineral Research, 2020
Patients with tumor‐induced osteomalacia (TIO), an acquired paraneoplastic condition characterized by osteomalacia due to hypophosphatemia, exhibit a similar clinical picture to those with X‐linked hypophosphatemic rickets/osteomalacia (XLH).
Y. Imanishi, N. Ito, Y. Rhee, Y. Takeuchi, C. Shin, Yutaka Takahashi, H. Onuma, Masahiro Kojima, M. Kanematsu, H. Kanda, Y. Seino, S. Fukumoto   +11 more
semanticscholar   +1 more source

Autoimmune hyperphosphatemic tumoral calcinosis in a patient with FGF23 autoantibodies [PDF]

, 2018
Hyperphosphatemic familial tumoral calcinosis (HFTC)/hyperostosis-hyperphosphatemia syndrome (HHS) is an autosomal recessive disorder of ectopic calcification due to deficiency of or resistance to intact fibroblast growth factor 23 (iFGF23). Inactivating
Burbelo, Christopher J. Romero, Daniela Egli-Spichtig, Emily Farrow, Farzana Perwad, Ichikawa, Lori C. Guthrie, Mary Scott Roberts, Michael J. Econs, Michael T. Collins, Peter D. Burbelo, Rachel I. Gafni, Shimada, Shoji Ichikawa, Uchida   +14 more
core   +1 more source

Oncogenic osteomalacia associated with mesenchymal tumor in the middle cranial fossa: a case report

Journal of Medical Case Reports, 2012
Introduction Tumor-induced osteomalacia is a paraneoplastic syndrome of hypophosphatemia. Osteomalacia causes multiple bone fractures and severe pain.
Chokyu Isao, Ishibashi Kenichi, Goto Takeo, Ohata Kenji   +3 more
doaj   +1 more source

OR13-3 Effects of Iron Isomaltoside versus Ferric Carboxymaltose on Hormonal Control of Phosphate Homeostasis: The PHOSPHARE-IDA04/05 Randomized Controlled Trials [PDF]

, 2019
Iron isomaltoside (IIM) and ferric carboxymaltose (FCM) are newer intravenous iron preparations that can be administered in high-doses to rapidly correct iron deficiency anemia (IDA).
Achebe, Maureen, Carpenter, Thomas, Econs, Michael, Imel, Erik, Peacock, Munro, Rubin, Janet, Thomsen, Lars, Weber, Thomas, Wolf, Myles, Zoller, Heinz   +9 more
core   +1 more source

Nutritional rickets & osteomalacia: A practical approach to management

The Indian journal of medical research, 2020
Defective mineralization of the growth plate and preformed osteoid result in rickets and osteomalacia, respectively. The leading cause of rickets worldwide is solar vitamin D deficiency and/or dietary calcium deficiency collectively termed as nutritional
S. Uday, W. Högler
semanticscholar   +1 more source

Burosumab therapy in children with x-linked hypophosphatemia [PDF]

, 2018
BACKGROUND X-linked hypophosphatemia is characterized by increased secretion of fibroblast growth factor 23 (FGF-23), which leads to hypophosphatemia and consequently rickets, osteomalacia, and skeletal deformities.
Boot, Annemieke M, Carpenter, Thomas O, Chen, Chao-Yin, Hogler, Wolfgang, Imel, Erik A, Kakkis, Emil, Linglart, Agnes, Mao, Meng, Martin, Javier San, Padidela, Raja, Portale, Anthony A, Skrinar, Alison, van\u27t Hoff, William, Whyte, Michael P   +13 more
core   +2 more sources

Osteomalacia due to Vitamin D Deficiency: A Case Report

Türk Osteoporoz Dergisi, 2020
Osteomalacia is a metabolic bone disease characterized by demineralization of the newly formed osteoid in adults. Vitamin D deficiency due to insufficient vitamin D intake, inadequate exposure to sunlight, and malabsorption of vitamin D are the most ...
Banu Ordahan, Kaan Uslu, Hatice Uğurlu
doaj   +1 more source

Simultaneous bilateral basicervical femoral neck fractures in a patient with osteomalacia: A case report and literature review

Clinical Case Reports, 2023
Key Clinical Message A thin patient with a history of eating disorders developed basicervical femoral neck fracture bilaterally and simultaneously due to vitamin D deficiency osteomalacia.
Kei Yokogawa, Keita Nagira, Toru Yonei, Tetsuya Otsuka, Hiroshi Hagino, Hideki Nagashima   +5 more
doaj   +1 more source