Results 31 to 40 of about 41,228 (298)
Clinical presentation and etiology of osteomalacia/rickets in adolescents
This study was conducted to determine the causes and clinical presentations of osteomalacia/rickets in adolescents seen at the King Abdulaziz Medical City (KAMC), Riyadh.
Mohammad A Hazzazi+4 more
doaj +1 more source
Tumor-induced osteomalacia – a mystery illness beyond aches, pains, and depression
Objective. Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterized by chronic hypophosphatemia and osteomalacia. We present case of a patient with a protracted clinical course of TIO.
Ni Huajing (Jing)+2 more
doaj +1 more source
The case of oncogenic hypophosphatemic osteomalacia
Osteomalacia is a systemic bone disease, characterized by an excessive accumulation of non-mineralized osteoid and an imbalance in the organic matrix formation and mineralization.
Anna K. Eremkina+5 more
doaj +1 more source
Targeted FGFR Blockade for the Treatment of Tumor-Induced Osteomalacia.
Targeted FGFR Blockade for Tumor-Induced Osteomalacia This letter describes the treatment of a patient with tumor-induced osteomalacia due to a phosphaturic mesenchymal tumor.
Iris R. Hartley+13 more
semanticscholar +1 more source
In adults with X‐linked hypophosphatemia (XLH), excess FGF23 impairs renal phosphate reabsorption and suppresses production of 1,25‐dihydroxyvitamin D, resulting in chronic hypophosphatemia and persistent osteomalacia.
K. Insogna+9 more
semanticscholar +1 more source
Oncogenic osteomalacia associated with mesenchymal tumor in the middle cranial fossa: a case report
Introduction Tumor-induced osteomalacia is a paraneoplastic syndrome of hypophosphatemia. Osteomalacia causes multiple bone fractures and severe pain.
Chokyu Isao+3 more
doaj +1 more source
Key Clinical Message A thin patient with a history of eating disorders developed basicervical femoral neck fracture bilaterally and simultaneously due to vitamin D deficiency osteomalacia.
Kei Yokogawa+5 more
doaj +1 more source
Strontium potently inhibits mineralisation in bone-forming primary rat osteoblast cultures and reduces numbers of osteoclasts in mouse marrow cultures [PDF]
The basic mechanisms by which strontium ranelate acts on bone are still unclear. We show that an important action of strontium salts is to block calcification in cultures of osteoblasts, the bone-forming cells.
A Barbara+44 more
core +3 more sources
Abstract Rickets is the clinical consequence of impaired mineralization of bone matrix throughout the growing skeleton in children, whilst osteomalacia is the result of this disturbance after the growth plates have fused in adults. The three major causes of rickets and osteomalacia are vitamin D deficiency, renal tubular dysfunction, and abnormalities
Whyte, M, Thakker, R
openaire +4 more sources