Results 61 to 70 of about 26,453 (213)

Post-Gastrectomy Osteomalacia Mimicking Rheumatologic Disorders: A Case Report

Journal of the ASEAN Federation of Endocrine Societies, 2016
Osteomalacia is one of the post-gastrectomy complications resulting from the impaired absorption of vitamin D and calcium.1 Vitamin D deficiency or osteomalacia can be diagnosed by clinical, biochemical and radiographic parameters, and bone biopsy.
Than Than Aye, Htar Ni Aye
doaj  

Proximal myopathy in lacto-vegetarian Asian patients responding to Vitamin D and calcium supplement therapy - two case reports and review of the literature

Journal of Medical Case Reports, 2011
Introduction Severe proximal myopathy can occasionally be the first presenting complaint of patients with osteomalacia. This may lead to investigations and misdiagnosis of a neuromuscular disease, rather than a metabolic bone disease.
Sreenan Seamus, Barry Maurice, Thabit Hood, Smith Diarmuid   +3 more
doaj   +1 more source

How I treat iron‐refractory iron deficiency anaemia—An expert opinion‐based treatment guidance for children and adults

British Journal of Haematology, Volume 206, Issue 4, Page 1067-1076, April 2025.
In iron‐refractory iron deficiency anaemia, inappropriately elevated hepcidin levels impair enteral iron absorption and iron release from macrophages by interacting with ferroportin. Oral iron supplements (containing ~30 mg Fe2+ per 100 mg) are generally ineffective due to this hepcidin–ferroportin interaction although, in some cases, this can be ...
V. Hoving, A. E. Donker, S. E. M. Schols, D. W. Swinkels   +3 more
wiley   +1 more source

‘Bone Health—Across a Woman's Lifespan’

Clinical Endocrinology, Volume 102, Issue 4, Page 389-402, April 2025.
ABSTRACT Despite a high burden of osteoporosis and minimal trauma fractures worldwide, there is still a treatment gap in timely diagnosis and optimal treatment. There is also a lack of international consensus and guidelines on the management of bone fragility in premenopausal women.
Gabrielle Stokes, Madhuni Herath, Navira Samad, Anne Trinh, Frances Milat   +4 more
wiley   +1 more source

Osteomalacia: desde la sospecha clínica al tratamiento. Revisión del tema

Revista Colombiana de Endocrinología, Diabetes y Metabolismo, 2019
El propósito de este artículo es presentar una revisión de la literatura acerca de la epidemiología, fisiopatología, manifestaciones clínicas y manejo de la osteomalacia.
V. Duque, N. Barrera, J. Gómez, V. Guerra, L. Ceballos, N. Aristizábal   +5 more
doaj   +1 more source

Treatment and outcomes of tumor-induced osteomalacia associated with phosphaturic mesenchymal tumors: retrospective review of 12 patients

BMC Musculoskeletal Disorders, 2017
BackgroundTumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterized by severe hypophosphatemia and osteomalacia. Nonspecific symptoms make the diagnosis elusive. In addition, locating the responsible tumor(s) is challenging.
Q. Zuo, Hong Wang, Wei Li, X.-H. Niu, Yan-hong Huang, Jia Chen, Yuchen You, B. Liu, Ai-min Cui, Wei-dong Deng   +9 more
semanticscholar   +1 more source

Unlocking the Mysteries of Rare Disease Drug Development: A Beginner's Guide for Clinical Pharmacologists

Clinical and Translational Science, Volume 18, Issue 4, April 2025.
ABSTRACT Clinical pharmacologists face unique challenges when developing drugs for rare diseases. These conditions are characterized by small patient populations, diverse disease progression patterns, and a limited understanding of underlying pathophysiology.
Mariam A. Ahmed, Bilal AbuAsal, Jeffrey S. Barrett, Karim Azer, Yuen Yi Hon, Salwa Albusaysi, Elizabeth Shang, Meng Wang, Maria Burian, Noha Rayad   +9 more
wiley   +1 more source

Combined pathology of bone tissue: osteoporosis and osteomalacia in patient with Parkinson’s disease (Clinical case report)

Bolʹ, Sustavy, Pozvonočnik, 2017
The article describes a case of combined osteoporosis and osteomalacia in a patient with Parkinson’s disease and vertebral pain syndrome. Osteomalacia caused by deficiency and metabolic disorders of vitamin D leads to osteoid mineralization impairment ...
V.V. Povoroznyuk, A.S. Musiienko, T.V. Parakhina, M.A. Bystrytska   +3 more
doaj   +1 more source

“We Are the Sons of Our Own Deeds”: Comparing Skeletal Health and Frailty Indices in Deceased Individuals Across 2000 Years of Milanese History

American Journal of Biological Anthropology, Volume 186, Issue 3, March 2025.
ABSTRACT Objectives In bioarchaeology, the concepts of resilience and frailty, and their quantification through indices, have gathered significant attention. This study is the first to apply, evaluate, and compare skeletal frailty indices and aims to trace frailty over time while identifying methodological challenges in their use on a sample ...
Petrosino, L. Biehler‐Gomez, K. E. Marklein, M. Mondellini, C. Moro, M. Mattia, A. M. Fedeli, C. Cattaneo   +7 more
wiley   +1 more source

Extracellular matrix: Dystroglycan interactions—Roles for the dystrophin‐associated glycoprotein complex in skeletal tissue dynamics

International Journal of Experimental Pathology, Volume 106, Issue 2, March 2025.
Abstract Contributions made by the dystrophin‐associated glycoprotein complex (DGC) to cell–cell and cell‐extracellular matrix (ECM) interactions are vital in development, homeostasis and pathobiology. This review explores how DGC functions may extend to skeletal pathophysiology by appraising the known roles of its major ECM ligands, and likely ...
Mark Hopkinson, Andrew A. Pitsillides
wiley   +1 more source