Results 61 to 70 of about 23,365 (210)

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source

OSTEOMALACIA DUE TO TYPE-I RENAL TUBULAR ACIDOSIS IN A MIDDLE AGED PAKISTANI WOMAN

Pakistan Armed Forces Medical Journal, 2009
Osteomalacia, one of the causes of reduced bone density, is a disorder of mineralization of newly formed bone matrix in adults. Though it is an uncommon disease in western world, but it is not that infrequent in Indian subcontinent.
Moizza Tahir, Jawad Khaliq Ansari
doaj   +2 more sources

Phosphopenic form of osteomalacia in a patient with FGF23 producing tumor

Научно-практическая ревматология, 2022
Oncogenic osteomalacia is an orphan disease caused by the overproduction of fibroblast growth factor 23 (FGF23) in tumors, which leads to impaired bone matrix mineralization. Typical laboratory changes are hypophosphatemia, increased alkaline phosphatase,
A. S. Pushkareva, E. E. Bibik, A. K. Eremkina, M. V. Degtyarev, N. G. Mokrysheva   +4 more
doaj   +1 more source

Systematic Optimization of an SLE‐DAPTAD LC–MS/MS Workflow for Simultaneous Quantification of Low‐Abundance Vitamin D3 Metabolites in Plasma

Rapid Communications in Mass Spectrometry, Volume 40, Issue 20, 30 October 2026.
ABSTRACT Rationale Liquid chromatography–tandem mass spectrometry (LC–MS/MS) analysis of vitamin D3 metabolites is analytically challenging because these compounds are structurally similar, strongly matrix‐associated, and have poor ionization efficiency.
Marzieh Amirmostofian, Michael D. Wiese, Paul H. Anderson, Peter Hoffmann   +3 more
wiley   +1 more source

Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs

The Anatomical Record, Volume 309, Issue 10, Page 2698-2724, October 2026.
Abstract Crocodilians, together with birds, are the only extant relatives to many extinct archosaur groups, making them highly important for interpreting paleopathological conditions in a phylogenetic disease bracketing model. Despite this, comprehensive data on osteopathologies in crocodilians remain scarce.
Alexis Cornille, Kyla Beguesse, Ewan Wolff, Clemens Zinner, Patrick Asbach, François Clarac, Florian Witzmann   +6 more
wiley   +1 more source

Tumor induced osteomalacia secondary to anaplastic thyroid carcinoma: A case report and review of the literature

Bone Reports, 2016
Context: Tumor induced osteomalacia related to anaplastic thyroid cancer has never been reported. Objective: We describe a case of tumor induced osteomalacia (TIO) in a patient with a fibroblast growth factor 23 (FGF-23) secreting anaplastic thyroid ...
Ejigayehu G. Abate, Victor Bernet, Cherise Cortese, Hillary W. Garner   +3 more
doaj   +1 more source

Review Article: Accelerating Coeliac Disease Clinical Trials—Beyond Celiac Meeting With Industry, Academics, Patients and the FDA

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 7, Page 890-896, October 2026.
A 2024 multi‐stakeholder meeting examined how to accelerate coeliac disease drug trials, highlighting key considerations in endpoint selection, symptom–histology alignment and feasibility. Progress requires patient‐centred trials showing symptomatic and intestinal improvement, appropriate gluten challenge, and early regulatory engagement, including ...
Lisa M. Fahey, Robert Anderson, Edwin Liu, Joseph A. Murray, Marie E. Robert, Jocelyn Anne Silvester, Kate Avery, Nelson Cheinquer, Kristie Grebe, Bhargav Tulabandula, Daniel A. Leffler, Beyond Celiac Coalition   +11 more
wiley   +1 more source

Bone histomorphometry in the evaluation of osteomalacia

Bone Reports, 2018
With the widespread use of measurement of bone mineral density to detect, diagnose, and monitor therapy in the management of osteoporosis, bone histomorphometry has largely been relegated to research settings and academic pursuits.
Arti Bhan, Shijing Qiu, Sudhaker D. Rao
doaj   +1 more source

Opportunistic Screening for Bone Demineralization by Whole Body CT in a Red‐Handed Howler Monkey (Alouatta belzebul) Under Human Care

Journal of Medical Primatology, Volume 55, Issue 5, October 2026.
ABSTRACT An eight‐year‐old male red‐handed howler monkey (Alouatta belzebul) underwent whole‐body computed tomography for gastrointestinal signs. Quantitative CT of the lumbar vertebrae opportunistically revealed severe bone hypoattenuation, demineralization, and deteriorated trabecular architecture.
Thaiza H. T. Fernandes, Ieverton C. C. Silva, João Marcelo Azevedo de Paula Antunes, Rhaysa Allayde Silva Oliveira, Julianne Moura da Silva, Yumma Bernardo Maranhão Valle, Webert Aurino Silva, Fabiano Séllos Costa   +7 more
wiley   +1 more source

Post-Gastrectomy Osteomalacia Mimicking Rheumatologic Disorders: A Case Report

Journal of the ASEAN Federation of Endocrine Societies, 2016
Osteomalacia is one of the post-gastrectomy complications resulting from the impaired absorption of vitamin D and calcium.1 Vitamin D deficiency or osteomalacia can be diagnosed by clinical, biochemical and radiographic parameters, and bone biopsy.
Than Than Aye, Htar Ni Aye
doaj