Results 21 to 30 of about 9,917 (88)

Establishing the Prevalence of Osteomalacia in Arab Adolescents Using Biochemical Markers of Bone Health

Nutrients, 2022
Nutrition-acquired osteomalacia is a bone mineralization disorder associated with dietary calcium and/or solar vitamin D deficiency, risk factors considered common in the Middle Eastern region.
N. Al-Daghri, S. Yakout, Shaun Sabico, K. Wani, S. D. Hussain, N. Aljohani, S. Uday, W. Högler   +7 more
semanticscholar   +1 more source

Epidemiology of Tumor-Induced Osteomalacia in Denmark

Calcified Tissue International, 2021
Tumor-induced osteomalacia (TIO) is a rare, acquired condition of phosphate wasting due to phosphaturic mesenchymal tumors. Because the incidence and prevalence of TIO is unknown, we conducted an observational cohort study using national Danish health ...
B. Abrahamsen, Christopher D. Smith, S. Minisola   +2 more
semanticscholar   +1 more source

Burosumab for the Treatment of Tumor‐Induced Osteomalacia

Journal of Bone and Mineral Research, 2020
Tumor‐induced osteomalacia (TIO) is caused by phosphaturic mesenchymal tumors producing fibroblast growth factor 23 (FGF23) and is characterized by impaired phosphate metabolism, skeletal health, and quality of life.
S. M. Jan de Beur, P. Miller, T. Weber, M. Peacock, K. Insogna, R. Kumar, F. Rauch, D. Luca, T. Cimms, M. S. Roberts, Javier San Martin, T. Carpenter   +11 more
semanticscholar   +1 more source

Impaired bone microarchitecture and strength in patients with tumor‐induced osteomalacia

Journal of Bone and Mineral Research, 2021
Some studies based on bone biopsy have demonstrated that in patients with tumor‐induced osteomalacia (TIO) the mineralization process of the bone matrix is profoundly disturbed. However, the interrelationship between clinical and biochemical features and
M. Zanchetta, F. Jerkovich, S. Nuñez, Y. Mocarbel, Analia Pignatta, N. Elias, A. Díaz, J. Roganovich, C. Vigovich, M. C. Balonga, A. C. Cohen, Giselle Mumbach, Sofía González, L. Plantalech, E. Fradinger, J. Zanchetta   +15 more
semanticscholar   +1 more source

Tumor mesenquimal fosfatúrico con rosetas gigantes: causa poco frecuente de osteomalacia oncogénica

, 2012
De Beur, Econs, Farrow, Folpe, Fukumoto, McCance, Prader, Radaideh, Seufert, Uramoto   +9 more
core   +2 more sources

Osteomalacia and Vitamin D Status: A Clinical Update 2020

JBMR Plus, 2020
Historically, rickets and osteomalacia have been synonymous with vitamin D deficiency dating back to the 17th century. The term osteomalacia, which literally means soft bone, was traditionally applied to characteristic radiologically or histologically ...
S. Minisola, L. Colangelo, J. Pepe, D. Diacinti, C. Cipriani, Sudhaker D. Rao   +5 more
semanticscholar   +1 more source

FGF23-related hypophosphatemic rickets/osteomalacia: diagnosis and new treatment.

Journal of Molecular Endocrinology, 2020
FGF23 is a phosphaturic hormone produced by bone. FGF23 reduces serum phosphate by suppressing proximal tubular phosphate reabsorption and intestinal phosphate absorption.
S. Fukumoto
semanticscholar   +1 more source

Prevalence of biochemical osteomalacia in adults undergoing vitamin D testing

Clinical Endocrinology, 2021
Prolonged severe vitamin D deficiency can cause osteomalacia, but the 25‐hydroxyvitamin D (25OHD) concentration below which this occurs is unknown. We investigated the prevalence of biochemical osteomalacia in adults with a measurement of 25OHD.
M. Bolland, A. Avenell, A. Grey
semanticscholar   +1 more source

Interim Analysis of a Phase 2 Open‐Label Trial Assessing Burosumab Efficacy and Safety in Patients With Tumor‐Induced Osteomalacia

Journal of Bone and Mineral Research, 2020
Patients with tumor‐induced osteomalacia (TIO), an acquired paraneoplastic condition characterized by osteomalacia due to hypophosphatemia, exhibit a similar clinical picture to those with X‐linked hypophosphatemic rickets/osteomalacia (XLH).
Y. Imanishi, N. Ito, Y. Rhee, Y. Takeuchi, C. Shin, Yutaka Takahashi, Hiroki Onuma, Masahiro Kojima, M. Kanematsu, H. Kanda, Y. Seino, S. Fukumoto   +11 more
semanticscholar   +1 more source

FGF23: Nueva diana terapéutica en los trastornos de la homeostasis del fósforo [PDF]

, 2017
El tejido óseo representa la mayor parte del esqueleto, el cual cubre nuestros órganos y sostiene nuestra fisiología, y se encuentra en constante renovación. Sus funciones básicas son de soporte, protección, movimiento, homeostasis mineral, producción de
Redondo Jiménez, Esther
core   +1 more source