Results 181 to 190 of about 28,897 (199)

Infective Endocarditis Caused by Abiotrophia defectiva: A Unique Case Complicated by Mitral Valve Perforation

open access: yesClinical Case Reports, Volume 13, Issue 4, April 2025.
ABSTRACT Abiotrophia defectiva, a nutritionally variant streptococcus, represents a rare yet serious cause of infective endocarditis (IE), accounting for 1%–2% of the total IE cases. It affects native valves in 10% of patients, and it is implicated in catastrophic complications.
Ra'ed Ababneh   +5 more
wiley   +1 more source

Post‐COVID‐19 Exacerbation of a Stable Fibrous Dysplasia: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 4, April 2025.
ABSTRACT Fibrous dysplasia (FD) is a rare, benign fibro‐osseous lesion characterized by replacement of normal bone with extensive fibrous stroma due to abnormalities in osteoblast differentiation. After puberty and during adulthood, FD lesions usually become quiescent. However, some cases show signs of regrowth and reactivation.
Mohammed Taib Fatih   +7 more
wiley   +1 more source

Synthesis of a Set of Staphylococcus Aureus Capsular Polysaccharide Type 1 Oligosaccharides Carrying Taurine Esters

open access: yesChemistry – A European Journal, Volume 31, Issue 24, April 25, 2025.
Staphylococcus aureus serotype 1 is a highly virulent pathogen and the capsular polysaccharide (CP1) has been shown to play an important role in virulence and be a target for opsonic antibodies. We here describe the synthesis of a set of CP1 oligosaccharides, varying in length and with different taurination patterns. Abstract Staphylococcus aureus is a
Kitt Emilie Østerlid   +4 more
wiley   +1 more source

Risk of Hypoglycemia Associated With Concomitant Use of Insulin Secretagogues and ACE Inhibitors in Adults With Type 2 Diabetes: A Systematic Review

open access: yesClinical Pharmacology &Therapeutics, Volume 117, Issue 4, Page 1005-1011, April 2025.
Insulin secretagogues and angiotensin‐converting enzyme inhibitors (ACEIs) are commonly co‐prescribed for patients with type 2 diabetes (T2D). Case reports suggesting that co‐administration of insulin secretagogues with ACEIs is associated with an increased risk of serious hypoglycemia have led to warnings regarding a drug–drug interaction in widely ...
Patricia Y. Chu   +4 more
wiley   +1 more source

Pamidronate‐Induced Clinical Remission in Chronic Non‐bacterial Osteomyelitis Is Associated with Reduced Vγ9Vδ2 T‐Cell Receptor Expression

open access: yesEuropean Journal of Immunology, Volume 55, Issue 4, April 2025.
In children with chronic non‐bacterial osteomyelitis, clinical and transcriptional changes in peripheral blood were examined after pamidronate treatment. Clinically effective treatment with pamidronate was associated with reduced expression of two genes (TRDV2 and TRGV9) that encode the subunits of the Vγ9Vδ2 T‐cell receptor.
Lily Watson   +6 more
wiley   +1 more source

Calcium Sulfate Bone Substitutes in Clinical Use: History, Material Properties, Application, and Outlook for the Future

open access: yesJournal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 113, Issue 4, April 2025.
ABSTRACT Calcium sulfate‐based materials have been used in medicine since the 19th century. Their application makes a significant part in the field of bone regeneration in biomedical engineering. Calcium sulfate is a versatile product that is used not only in the reconstruction of bone defects but also as an antibiotic carrier. Various types of calcium
Josina Straub   +6 more
wiley   +1 more source

Beyond Childhood: Adult and Adolescent Sickle Cell Disease and Outcomes in Northern Ghana

open access: yeseJHaem, Volume 6, Issue 2, April 2025.
ABSTRACT Background Adults and adolescents face different barriers to healthcare utilization compared to children. Objective To describe adult and adolescent sickle cell disease (SCD) and outcomes in northern Ghana. Methods This was a retrospective cohort study of SCD patients aged 13 years and above, admitted between January 1, 2021 and December 31 ...
Kwadwo Faka Gyan   +8 more
wiley   +1 more source

Systemic Inflammatory Diseases in Children With Sickle Cell Disease: A French Multicenter Observational Study on Diagnostic and Therapeutic Issues

open access: yesPediatric Blood &Cancer, Volume 72, Issue 4, April 2025.
ABSTRACT Background Systemic inflammatory diseases (SIDs) have been reported in patients with sickle cell disease (SCD), but clinical data in children are scarce. Objectives To identify clinical and laboratory features at diagnosis of SID in children with SCD and to describe their evolution.
Caroline Vinit   +19 more
wiley   +1 more source

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