Osteoporosis Diagnostics in Dental Radiology (Panoramic Radiograph): The Mini Osteoporosis Pre-Screening (MOPS). [PDF]
Geibel MA +4 more
europepmc +1 more source
Targeting Mitochondria in Aging‐Related Diseases: Therapeutic Potential and Obstacles
This article systematically summarized the specific mechanism of aging‐related diseases caused by mitochondrial dysfunction, and summarized the broad‐spectrum treatment methods and disease targeted treatment strategies for mitochondria. At the same time, it also pointed out the dilemma faced by mitochondrial targeted treatment.
Zijie Xiang +12 more
wiley +1 more source
The interplay between osteosarcopenia and intrinsic capacity: insights and associations with all-cause mortality in the Toledo Study for Healthy Aging. [PDF]
Baltasar-Fernandez I +36 more
europepmc +1 more source
Exploratory XPS Evidence for Ca–N Environments at the Organic–Mineral Interface in Bone
ABSTRACT Bone derives its remarkable mechanical properties from the nanoscale relationship between its organic matrix and mineral components. While interfacial interactions are known to affect bone mechanics, direct evidence of chemical bonding at this interface has been lacking.
Richard Leslie Abel +3 more
wiley +1 more source
Cone Beam Computed Tomography of Bonejaws in Patients With Primary Osteoporosis: A Systematic Review. [PDF]
Frassineti I +7 more
europepmc +1 more source
Addressing systemic biases in traditional aging clocks, we introduce PAAG, a context‐aware multi‐omics metric derived from the pre‐trained AOE‐Net. PAAG accurately captures localized aging acceleration, demonstrating superior predictive power for chronic disease risks and clinical outcomes across diverse aging populations.
Feng‐Ao Wang +12 more
wiley +1 more source
Preoperative osteosarcopenia predicts adverse outcomes in patients undergoing transcatheter aortic valve implantation. [PDF]
Sugiura H +3 more
europepmc +1 more source
Aging‐related decline of muscle Bmal1 drives bone loss in mice by disrupting Hmox1 and increasing IL‐1α, which promotes osteoclast activity. Time‐restricted feeding reestablishes diurnal Hmox1 expression, reduces IL‐1α, and alleviates osteoporosis, offering a potential therapeutic strategy. ABSTRACT Osteoporosis, a common metabolic bone disorder linked
Kai Huang +5 more
wiley +1 more source
Managing Periprosthetic Fracture of the Proximal Femur Using Total Hip Arthroplasty in a Patient with Sequelae of Poliomyelitis: Case Report and Literature Review. [PDF]
Magetsari RMSN +3 more
europepmc +1 more source
Expanding Phenotype of GINS1 Deficiency: A Case Report and Review of the Literature
The authors present a novel case and review of individuals with GINS1 deficiency, causing severe growth restriction and combined immunodeficiency. Only the ninth case of this ultrarare disorder, it highlights the role of these variants in disease, glaucoma as a feature, and the possibility of immunodeficiency without infections in affected individuals.
Michael P. Mackley +6 more
wiley +1 more source

