Results 41 to 50 of about 10,418 (205)

Further understanding on osteopetrotic femoral fractures: a case report and literature review

BMC Surgery, 2021
Background Osteopetrosis is a genetic disease characterized by defects in osteoclast formation and function. There were a few cases of subtrochanteric femur fractures treated with dynamic hip screw (DHS) in patients with osteopetrosis, but unfortunately ...
Haiqi Ding, Hongjiang Chen, Haiming Lin, Jiankun Xu, Zhonglian Huang, Wensheng Li, Jun Hu   +6 more
doaj   +1 more source

COX‐2 in Fracture Callus Chondro‐Osseous Junction Osteoclasts Regulates Chondrocyte Hypertrophy and Callus Vasculogenesis

Journal of Orthopaedic Research, Volume 43, Issue 11, Page 1973-1986, November 2025.
ABSTRACT Cyclooxygenase‐2 (COX‐2) activity is necessary for bone fracture healing to proceed normally. COX‐2 is encoded by Ptgs2 and is expressed by several cell types during fracture healing, suggesting that COX‐2 regulates multiple processes to affect fracture healing.
Marc Teitelbaum, Hsuan‐Ni Lin, Maya D. Culbertson, Charlene Wetterstrand, J. Patrick O'Connor   +4 more
wiley   +1 more source

Granulocyte Transfusions in Pediatric Hemato‐Oncology: Neutrophil Response and CRP Kinetics

Pediatric Blood &Cancer, Volume 72, Issue 11, November 2025.
ABSTRACT Background Granulocyte transfusions (GTXs) are used in neutropenic pediatric hemato‐oncology patients with infections unresponsive to antimicrobial therapy, but their clinical benefit remains uncertain. Methods We retrospectively reviewed all pediatric patients who received GTXs between 2013 and 2023 at a tertiary medical center.
Aviv Sever, Ron Rabinowicz, Shlomit Barzilai‐Birenboim, Salvador Fisher, Ronit Goldman Levi, Assaf Yanir, Jerry Stein, Efraim Bilavsky, Joanne Yacobovich, Vered Yahalom   +9 more
wiley   +1 more source

A Case Report of Malignant Infantile Osteopetrosis

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2011
BACKGROUND AND OBJECTIVE: Infantile osteopetrosis is a rare genetic fetal and metabolic congenital osteo- disorder. It results from dysfunction or lack of osteoclasts. Most of patients die from anemia, bleeding and infection.
Khorashadizadeh F, Bayani Gh, Soltani Z
doaj  

Osteopetrosis complicated by multilevel spondylolysis

Radiology Case Reports
Osteopetrosis is a heterogenous group of inheritable disorders which manifests as increased bone density and brittleness. The most common and mildest variant typically presents in adulthood with bone pain and pathologic fractures, including spondylolysis.
William W. Pryor, III, MD, Carolina V. Guimaraes, MD, Lane F. Donnelly, MD   +2 more
doaj   +1 more source

Salvianolic Acid A Mitigates Osteoporotic Bone Loss by Repressing Reactive Oxygen Species via the Nrf2–HO‐1 Pathway

Phytotherapy Research, Volume 39, Issue 11, Page 4977-4990, November 2025.
ABSTRACT Osteoporosis, characterized by osteoclastic bone resorption, has been the focus of research. Studies implicate that reactive oxygen species (ROS) accumulate intracellularly during osteoclastogenesis. Salvianolic acid A (SAA), a compound derived from Salvia miltiorrhiza, has been widely used to treat cardiovascular and cerebrovascular disorders,
Hao Qiu, Chenhui Cai, Ying Zhang, Sizhen Yang, Xu Hu, Tongwei Chu   +5 more
wiley   +1 more source

UK recommendations for chimerism testing and monitoring following allogeneic haematopoietic stem cell transplantation (HSCT): Best practice consensus guidelines from the British Society for Blood and Marrow Transplant and Cellular Therapies (BSBMTCT), NHS England Genomic Laboratory Hub (GLH) Haematological Malignancies Working Group, UK Cancer Genetics Group (UKCGG) and the UK National External Quality Assessment Service for Leucocyte Immunophenotyping (UK NEQAS LI)

British Journal of Haematology, Volume 207, Issue 5, Page 1802-1814, November 2025.
Summary In allogeneic haematopoietic stem cell transplantation (HSCT), important clinical decisions depend upon assessment of chimerism, including immunosuppressant dosing and donor lymphocyte infusions (DLI), which in turn can have major impacts on disease control, graft‐versus‐host disease (GVHD), immunity and ultimately patient survival.
Andrew Clark, Hazel Clouston, Kanchan Rao, Najeem Folarin, Josu De la Fuente, Angela Hamblin, Eduardo Olavarria, Debbie Richardson, Polly Talley, Victoria Potter, Justin Loke, Terri McVeigh, John Snowden   +12 more
wiley   +1 more source

Three cases of Osteopetrosis in a family

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2004
Background and Objective: Osteopetrosis is a rare congenital bone disease, characterized by generalized increase in skeletal density. It has been recognized several types of osteopetrosis with varying severity.
N Nakhjavani
doaj  

Maxillary osteomyelitis in Albers-Schönberg disease: A rare presentation

Journal of Dr. NTR University of Health Sciences, 2018
Osteopetrosis (Albers-Schönberg disease) is a rare congenital disorder in which the bones become overly dense. This results from an imbalance between the formation of bone and the breakdown of bone.
Borra Venkata Naga Koti Jyothi Pavan, Gouri Shankar Kejriwal, Bagadi Lava Kumar   +2 more
doaj   +1 more source

Congenital Nasal Choristoma (Hairy Polyp) in a Term Neonate: A Case Report and Review of the Literature

Clinical Case Reports, Volume 13, Issue 10, October 2025.
A term newborn with nasal mass caused by choristoma (hairy poly). ABSTRACT We describe the case of a term Hispanic male neonate with a nasal septum/inferior turbinate choristoma. The presented case report includes a review of the historical, radiological, surgical, and histological features, and the literature on this entity.
Surasak Puvabanditsin, Ali G. Saad, Arun Sangam, Anthony Poltronetti, Su Young Park, Amrryn Halari, Rajeev Mehta   +6 more
wiley   +1 more source