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Performance of novel biomarkers for prediction of diabetic kidney disease in patients with diabetes mellitus. [PDF]
Ann MedZou LX, Hou ZL, Qian CH, Wang X, Sun L.
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Osteopontin promotes infarct repair
Basic Research in Cardiology, 2022Understanding how macrophages promote myocardial repair can help create new therapies for infarct repair. We aimed to determine what mechanisms underlie the reparative properties of macrophages. Cytokine arrays revealed that neonatal cardiac macrophages from the injured neonatal heart secreted high amounts of osteopontin (OPN).
I. Rotem +9 more
semanticscholar +3 more sources
The role of osteopontin in the progression of solid organ tumour
Cell Death and Disease, 2018 Osteopontin (OPN) is a bone sialoprotein involved in osteoclast attachment to mineralised bone matrix, as well as being a bone matrix protein, OPN is also a versatile protein that acts on various receptors which are associated with different signalling ...
Hailin Zhao, Qian Chen, Azeem Alam
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The multiple functions and mechanisms of osteopontin
Clinical Biochemistry, 2018Makbule Gezmen Karadağ
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Arteriosclerosis, Thrombosis, and Vascular Biology, 2007 Osteopontin is an arginine-glycine–aspartate (RGD) containing adhesive glycoprotein first identified in bone but subsequently detected in many other tissues, including, dentin, cartilage, kidney, and vascular tissues.1–3 It is expressed by a wide variety of inflammatory cells (eg, macrophages, T lymphocytes, NK cells), and, to a lesser extent, by ...
Lucy Liaw
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Osteopontin as a multifaceted driver of bone metastasis and drug resistance
Pharmacological Research, 2019 Xiaocong Pang, Kan Gong, Yi-Min Cui
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Drug News & Perspectives, 1998
Although osteopontin (OP) has been shown to play a role in bone mineralization and to mediate bone cell adhesion, its function in other tissues is not yet known. The sequences of OP from seven species have been reported; some of the sequences that are conserved in all seven species and their functions are mentioned.
M A, Chellaiah, K A, Hruska
openaire +2 more sources
Although osteopontin (OP) has been shown to play a role in bone mineralization and to mediate bone cell adhesion, its function in other tissues is not yet known. The sequences of OP from seven species have been reported; some of the sequences that are conserved in all seven species and their functions are mentioned.
M A, Chellaiah, K A, Hruska
openaire +2 more sources