Results 141 to 150 of about 224,404 (241)

Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang   +4 more
wiley   +1 more source

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

open access: yesPhytotherapy Research, Volume 40, Issue 11, Page 6709-6747, November 2026.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi   +5 more
wiley   +1 more source

The Effects of Risedronate Therapy Combined With Vitamin D and Calcium on Biochemical Markers of Bone Turnover and Bone Mineral Density in Postmenopausal Osteoporosis

open access: yes, 2004
The aim of the study was to investigate the effects of risedronate therapy combined with vitamin D and calcium on bone mineral density(BMD) and biochemical markers of bone turnover in patients with primary postmenopausal osteoporosis.
Sacide Atalay   +5 more
core  

Diffuse cranial vault hyperostosis associated with long‐term antiepileptic therapy: Autopsy findings and differential diagnostic considerations

open access: yesJournal of Forensic Sciences, Volume 71, Issue 6, Page 2981-2986, November 2026.
Abstract Diffuse cranial vault hyperostosis is an uncommon finding and may present a diagnostic challenge in clinical and forensic practice. We report the case of a 53‐year‐old woman with a long‐standing history of epilepsy treated with phenytoin and sodium valproate who collapsed at home suddenly and died despite resuscitative efforts.
Maria Piagkou   +7 more
wiley   +1 more source

Bone Anabolic Treatment in Patients With Chronic Kidney Disease: A Systematic Review

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 5, November 2026.
ABSTRACT Background Chronic kidney disease (CKD) associated osteoporosis leads to an increased risk of bone fracture in patients with CKD. Evidence on the efficacy and safety of anti‐osteoporotic medications is limited for this group. This systematic review aimed to examine the efficacy and safety of anabolic parathyroid hormone (PTH) treatment in ...
Huriye Seyma Kafa   +2 more
wiley   +1 more source

Two Years of Alendronate and Calcitonin Treatments for Osteoporosis in Postmenopausal Women - Original Investigation

open access: yes, 2006
This study was to compare and research the effects of alendronate and calcitonin treatments with 2 years duration in women with postmenopausal osteoporosis.
Gülnur Taşçı Bozbaş   +3 more
core  

YTHDF3 Enhances Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in Osteoporosis by Promoting TBX19 Expression

open access: yesCell Proliferation, Volume 59, Issue 11, November 2026.
In this study, OP‐BMSCs were successfully isolated from OVX osteoporotic rats. Mechanistic investigations revealed that the RNA‐binding protein YTHDF3 significantly upregulates Tbx19 expression by enhancing the stability of Tbx19 mRNA. Elevated Tbx19 levels, in turn, activate key osteogenic molecules, effectively promoting the differentiation of OP ...
Qianke Tao   +9 more
wiley   +1 more source

Comparison of Different Treatment Protocols in Osteoporosis

open access: yes, 2003
The aim of this study was to compare the effectiveness of different medical treatment protocols in osteoporosis. For this purpose 153 postmenopausal women who were diagnosed as osteoporosis were randomly divided into 4 groups and given different medical ...
Ali Aydeniz   +2 more
core  

Artificial Intelligence‐Driven Precision Bisphosphonate Therapy in Osteoporosis: Mechanisms, Clinical Applications, Risks, and Future Directions

open access: yesOrthopaedic Surgery, Volume 18, Issue 11, Page 2309-2319, November 2026.
This comprehensive review integrates 17 benchmark studies to illustrate the transition of osteoporosis management toward precision medicine. The schematic highlights three key clinical applications: AI‐driven opportunistic screening from routine CTs, precision pharmacotherapy selection, and the predictive prevention of adverse events like MRONJ ...
Xiang Yao   +7 more
wiley   +1 more source

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