Results 51 to 60 of about 48,647 (281)

When, where and how osteoporosis-associated fractures occur: An analysis from the global longitudinal study of osteoporosis in women (GLOW) [PDF]

, 2013
Objective: To examine when, where and how fractures occur in postmenopausal women. Methods: We analyzed data from the Global Longitudinal Study of Osteoporosis in Women (GLOW), including women aged ≥55 years from the United States of America, Canada ...
Anderson, Frederick A, Adachi, JD, Stephen H Gehlbach, Universitat Autònoma de Barcelona. Departament de Medicina, Adachi, Jonathan D., Chapurlat, Roland D., Frederick H Hooven, Díez Pérez, Adolfo, Nelson B Watts, Adachi, Jonathan D, Nieves, JW, Netelenbos, J.C., Lyn March, Boonen, S, Saag, Kenneth G., Compston, Juliet E., Roux, Christian, Pfeilschifter, Johannes, Rossini, Maurizio, Boonen, Steven, Pfeilschifter J, Ethel S Siris, Boonen S, Siris, E.S., Anderson, F.A., LaCroix, Andrea Z., Siris, Ethel S., Adami, Silvano, Adami, S., Watts NB, Jeri W Nieves, Lacroix, A.Z., Watts, NB, Gehlbach SH, Roux, C., Maurizio Rossini, Compston, JE, Gehlbach, S.H., Costa AG, Pfeilschifter, J., Rossini, M., Christian Roux, Boonen, S., Greenspan SL, Susan L Greenspan, Watts, N.B., Compston JE, Costa, Aline G. [UNIFESP], Greenspan, Susan L., Gehlbach, SH, March, L., Adami, S, Saag KG, Roux, C, Adachi JD, Saag, KG, Anderson, Frederick A., Greenspan, SL, Compston, Juliet E, Anderson FA Jr, Saag, Kenneth G, Hooven, Frederick H., Netelenbos JC, Cooper, C., March, Lyn, Díez Pérez A, Nieves, Jeri W., Cooper, C, Adachi, J.D., March, L, Nieves, Jeri W, Hooven, F.H., Andrea Z LaCroix, Silverman S, LaCroix, Andrea Z, Kenneth G Saag, Watts, Nelson B, Adolfo Díez-Pérez, Chapurlat, RD, Saag, K.G., Aline G Costa, Silverman, Stuart, Rossini, M, Juliet E Compston, Compston, J.E., Diez-Perez, A., Diez-Perez, Adolfo, Wyman, Allison, Stuart Silverman, Chapurlat, Roland D, Anderson Jr, Frederick A., Nieves JW, Silverman, S., Netelenbos, J. Coen, Jonathan D Adachi, Roux C, Cyrus Cooper, Gehlbach, Stephen H., Siris, Ethel S, Netelenbos, J Coen, Roland D Chapurlat, Siris, ES, Frederick A Anderson, March L, Pfeilschifter, J, Costa, A.G., Hooven, FH, Allison Wyman, LaCroix, AZ, Gehlbach, Stephen H, Lacroix AZ, Chapurlat, Roland, Wyman, A., Chapurlat, R.D., Greenspan, Susan L, Díez-Pérez, A, Silvano Adami, Anderson, FA, Cooper, Cyrus, Costa, Aline G, Chapurlat RD, Wyman, A, J Coen Netelenbos, Hooven, Frederick H, Hooven FH, Siris ES, Steven Boonen, Wyman A, Silverman, S, Costa, Aline G., Greenspan, S.L., Watts, Nelson B., Johannes Pfeilschifter, Netelenbos, JC, Nieves, J.W., Costa, AG, Cooper C   +136 more
core   +1 more source

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

Advanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao, Hai‐Jin Zeng, Zun Wang, Chun‐Gu Hong, Yi‐Juan Tan, Yan‐Xin Duan, Jing‐Yao Luo, Ming‐Jie Luo, Yi‐Wei Liu, Xin Wang, Yi Luo, Teng‐Fei Wan, Yong Zhou, Zheng‐Guang Wang, Guo‐Wen Hu, Hao Yin, Xin‐Yue Hu, Zhen‐Xing Wang, Ze‐Hui He, Si‐Yi Cheng, Wei Du, Zhe Guan, Hai‐Li Lang, Hong‐Ji Liu, Jia Cao, Peng Chen, Jiang‐Hua Liu, Hui Xie, Chun‐Yuan Chen   +28 more
wiley   +1 more source

Improved prediction of fracture risk leveraging a genome-wide polygenic risk score

Genome Medicine, 2021
Background Accurately quantifying the risk of osteoporotic fracture is important for directing appropriate clinical interventions. While skeletal measures such as heel quantitative speed of sound (SOS) and dual-energy X-ray absorptiometry bone mineral ...
Tianyuan Lu, Vincenzo Forgetta, Julyan Keller-Baruch, Maria Nethander, Derrick Bennett, Marie Forest, Sahir Bhatnagar, Robin G. Walters, Kuang Lin, Zhengming Chen, Liming Li, Magnus Karlsson, Dan Mellström, Eric Orwoll, Eugene V. McCloskey, John A. Kanis, William D. Leslie, Robert J. Clarke, Claes Ohlsson, Celia M. T. Greenwood, J. Brent Richards   +20 more
doaj   +1 more source

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen, Zhidong Liu, Yanhang Sun, Xiaojun Xu, Zhexiao Lan, Junhao Zhao, Peitao Xu, Guiwen Ye, Jinteng Li   +8 more
wiley   +1 more source

COMBINED POSTERIOR-ANTERIOR SURGERY FOR OSTEOPOROTIC DELAYED VERTEBRAL FRACTURE WITH NEUROLOGIC DEFICIT [PDF]

, 2014
2014-08With the aging of society, osteoporotic thoracolumbar compression fracture is a concern. This fracture occurs occasionally; however, some cases progress to neural compromise due to delayed vertebral body collapse requiring surgery.
MACHINO, MASAAKI, YUKAWA, YASUTSUGU, ISHIGURO, NAOKI, KATO, FUMIHIKO, NAKASHIMA, HIROAKI, ITO, KEIGO   +5 more
core   +1 more source

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

Advanced Science, EarlyView.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu, Meiqin Zhang, Ting Wu, Erfan Wei, Andrei Y. Hancharou, Zeying Wang, Zijuan Wang, Letian Lv, Likun Wu, Xingtong Pan, Qiyue Zhu, Xinyi Dong, Hao Liu, Yongsheng Zhou   +13 more
wiley   +1 more source

Osteoporotic vertebral fractures

Neurosurgical Focus, 2001
Osteoporosis is a significant public health problem. Vertebral fractures are the most common fracture in patients with osteoporosis, occurring in approximately 750,000 cases each year. The fractures may cause acute or chronic pain, reduce the quality of life, and shorten life expectancy.
openaire   +2 more sources

Hip fracture risk assessment: Artificial neural network outperforms conditional logistic regression in an age- and sex-matched case control study [PDF]

, 2013
Copyright @ 2013 Tseng et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution,
Li-Wei Hung, Shieh, J-S, Abbod, MF, Wo-Jan Tseng, Jinn Lin, Hung, L-W, Jiann-Shing Shieh, Maysam F Abbod, Tseng, Wo-Jan, Tseng, W-J, Lin, J   +10 more
core   +1 more source

A Periosteum‐Inspired Janus Piezoelectric Scaffold Using Bioenergetic‐Driven H‐Type Vascularization for Diabetic Bone Regeneration

Advanced Science, EarlyView.
A periosteum‐inspired Janus piezoelectric scaffold converts micromechanical forces into electrical signals and synergizes with controlled resveratrol release. This dual action reprograms endothelial metabolism, drives H‑type vessel formation, and restores bone–vessel coupling in diabetic bone defects.
Kai Wang, Kai Jiang
wiley   +1 more source

Treatment of osteoporotic vertebral fractures

Orthopaedics & Traumatology: Surgery & Research, 2021
Osteoporosis is a public health problem that is contributing to an increasing number of osteoporotic vertebral fractures. The aim of this lecture is to summarize the current state of knowledge about osteoporotic fractures by answering five questions. 1/How does the spine typically age and how is osteoporosis diagnosed?
Solène, Prost, Sébastien, Pesenti, Stéphane, Fuentes, Patrick, Tropiano, Benjamin, Blondel   +4 more
openaire   +2 more sources