Results 101 to 110 of about 299,351 (228)

Development of a prediction model for recurrent vertebral fractures in patients two years after vertebral augmentation using noninvasive data: a retrospective study

BMC Musculoskeletal Disorders
Objectives By utilizing noninvasive data to analyze the risk factors for recurrent vertebral fractures in patients two years after vertebral augmentation and establishing a predictive model, the aim is to enhance the management of fragility fractures and
Yulu Fan, Weifeng Ma, Tao Li, Yu Kong, Na Zou   +4 more
doaj   +1 more source

Risk Factor Analysis of Osteoporotic Fractures of Post-menopausal Women

, 2009
[[abstract]]Osteoporotic fracture poses a substantial clinical, economic, and health-related burden to the individual, family, society and national heath-care system.
li pao kui
core  

Teriparatide Topical Delivery Supports Osseointegration in Ovariectomized Rats Receiving Cafeteria Diet and Bisphosphonate: An In Vivo Experimental Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Background Postmenopausal osteoporosis associated with cafeteria diet and bisphosphonate therapy may impair peri‐implant bone repair. Therefore, strategies to enhance osseointegration are needed. Aim This study investigated whether teriparatide‐coated implant surfaces enhance osseointegration in a rodent model of estrogen deficiency (OVX) and ...
Ana Cláudia Ervolino da Silva, Fábio Roberto de Souza Batista, Jaqueline Suemi Hassumi, Naara Gabriela Monteiro, Marina Santos Fernandes, Luana Marotta Reis Vasconcellos, Gabriel Mulinari‐Santos, Reinhard Gruber, Paulo Noronha Lisboa‐Filho, Roberta Okamoto   +9 more
wiley   +1 more source

YTHDF3 Enhances Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in Osteoporosis by Promoting TBX19 Expression

Cell Proliferation, EarlyView.
In this study, OP‐BMSCs were successfully isolated from OVX osteoporotic rats. Mechanistic investigations revealed that the RNA‐binding protein YTHDF3 significantly upregulates Tbx19 expression by enhancing the stability of Tbx19 mRNA. Elevated Tbx19 levels, in turn, activate key osteogenic molecules, effectively promoting the differentiation of OP ...
Qianke Tao, Qiaonan Ye, Chengpeng Yang, Yuping Xie, Xuemei Long, Long Bai, Zhiyuan Zhang, Qianwei Li, Dan Tan, Jingang Xiao   +9 more
wiley   +1 more source

Osteoporotic vertebral fractures: current concepts of conservative care.

, 2011
Introduction: Osteoporotic vertebral compression fractures (VCFs) are a growing public health problem with important socio-economic effects in western countries. In the USA, 10 million people over 50 suffer from osteoporosis.
DENARO, LUCA, Maffulli N, Denaro V., Loppini M, Longo UG   +4 more
core   +1 more source

Differentiation of Traumatic Osteoporotic and Non-Osteoporotic Vertebral AO A3 Fractures by Analyzing the Posterior Edge Morphology—A Retrospective Feasibility Study

, 2020
Background: Differentiation between traumatic osteoporotic and non-osteoporotic vertebral fractures is crucial for optimal therapy planning. We postulated that the morphology of the posterior edge of the cranial fragment of A3 vertebral fractures is ...
Sebastian Klingebiel, Michael J. Raschke, René Hartensuer, Thomas Vordemvenne, Jens Lohmaier, Steffen Roßlenbroich, Dirk Wähnert   +6 more
core   +1 more source

Genetically Proxied GIP‐GIPR Pathway Perturbation and Fracture Risk

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To determine whether genetic proxies for incretin pathway perturbation are associated with fracture risk and bone mineral density, providing human genetic evidence relevant to the skeletal safety of incretin‐based therapies. Materials and Methods We conducted drug‐target Mendelian randomisation using cis genetic variants near GIP, GIPR ...
Wenjie Cheng, Weijie Liu, Jie Wei, Chao Zeng, Houchen Lyu, Sizheng Steven Zhao   +5 more
wiley   +1 more source

Denosumab discontinuation and fracture risk: getting the balance right

Internal Medicine Journal, EarlyView.
Abstract Denosumab is a highly effective therapy for osteoporosis. Since its approval by the Therapeutic Goods Administration (TGA) in 2010, use of denosumab has surged across Australia, delivering substantial fracture‐prevention benefits to tens of thousands of patients. However, stopping denosumab may lead to acute loss of bone with an increased risk
Albert S. Kim, Christian M. Girgis
wiley   +1 more source

Incidence, prevalence, and predictors of osteoporotic fracture in adult lung transplant recipients

JHLT Open
Background: As life expectancy following lung transplantation (LT) improves, vulnerability to glucocorticoid-induced osteoporotic fractures is increased.
Elisabeth Ng, Shanal Kumar, Eldho Paul, Daniel Bennett, Luisa Rosi, Louise Fuller, Lauren Chiu, Shoshana Sztal-Mazer, Steven Ivulich, Greg Snell, Leon A. Bach, Kathryn L. Hackman   +11 more
doaj   +1 more source

Vertebroplasty and Kyphoplasty in the Treatment of Osteoporotic Vertebral Compression Fractures

, 2004
In our study which is carried out to detect the effect of kyphoplasty over acute vertebral fractures, 8 patients; presenting with 6 osteoporotic, 1 tumoral, 1 traumatic acute vertebra fractures underwent kyphoplasty procedure at a total of 12 levels.
Sedat Çağlı, Mehmet Zileli, Sertaç İşlekel, Işıl Taş, Simin Hepgüler   +4 more
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