Results 201 to 210 of about 51,628 (264)

Development and Validation of an AI‐Integrated System for Automated Fracture Detection and Pedicle Puncture Planning in Lumbar Osteoporotic Vertebral Compression Fractures Based on the Nine‐Grid Area Division Method

open access: yesOrthopaedic Surgery, Volume 18, Issue 6, Page 1266-1277, June 2026.
This study developed a three‐module AI‐integrated software. Its effectiveness was verified, and it was confirmed to have certain transformation potential. ABSTRACT Objective The clinical application of the Nine‐grid Area Division Method for pedicle puncture in L‐OVCF is limited by high technical thresholds and low efficiency.
Weiyang Zuo   +12 more
wiley   +1 more source

Osteoporotic spinal fractures: diagnosis and treatment.

open access: yes
Aim: The aim of this paper is to analyse the literature findings on osteoporotic vertebral fractures, provide reliable evidence on effective treatment strategies for osteoporotic vertebral fractures, and to describe a series of clinical cases ...
Riabec, Pavel,
core  

Osteoblast‐Derived Osteomodulin Suppresses Bone Loss in Osteoporosis by Inhibiting Osteoclastogenesis

open access: yesThe FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Osteoblast‐derived matricellular protein osteomodulin (OMD) critically regulates bone remodeling homeostasis via directly and competitively binding to RANKL, the master cytokine driving osteoclast formation. OMD shares overlapping binding sites on RANKL with osteoprotegerin and functional receptor RANK.
Meiling Jing   +9 more
wiley   +1 more source

SCD1 Regulates Osteoclast Differentiation by Modulating Arachidonic Acid Metabolism and Mitochondrial Homeostasis

open access: yesThe FASEB Journal, Volume 40, Issue 10, 31 May 2026.
This graphical abstract illustrates that SCD1 inhibition by A939572 or the targeted nanovesicle POCM‐NP@A939572 reprograms arachidonic acid metabolism via the COX1‐HPGDS‐PGD2 axis and impairs mitochondrial homeostasis, thereby suppressing osteoclastogenesis and alleviating bone loss in osteoporosis.
Yihao Zhao   +12 more
wiley   +1 more source

Metabolomic biomarkers of rest-activity rhythms in older men: results from the Osteoporotic Fractures in Men (MrOS) study. [PDF]

open access: yesSleep
Zhang L   +11 more
europepmc   +1 more source

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