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Lippincott's Bone and Joint Newsletter, 2009 Abstract In this chapter we will discuss the types of fractures that occur with osteoporosis and the reasons behind them. Additionally we will look at the treatments available for such . One in two women and one in five men over the age of 50 are at risk of a fracture (broken bone) due to osteoporosis.
Reiner Bartl, Bertha Frisch
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The prevention of osteoporotic fractures
The Journal of Bone and Joint Surgery. British volume, 2005The World Health Organisation defined osteoporosis in 1994 as a condition in which the bone mineral density (BMD) is 2.5 sds or more below the mean seen in young normal subjects.[1][1] By this definition, a quarter of all post-menopausal American Caucasians, in total 26 million white American ...
M K, Karlsson, P, Gerdhem, H G, Ahlborg
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Epidemiology of osteoporotic fractures
Osteoporosis International, 2004Several osteoporotic fractures such as hip fractures have a very high morbidity and mortality, and there are similar new findings for vertebral fractures. There have been several definitions of an osteoporotic fracture, and recently updated definitions have specified fractures occurring at a site associated with low BMD and which increase in incidence ...
Olof, Johnell, John, Kanis
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Current Osteoporosis Reports, 2014
Animal models are widely used to investigate the pathogenesis of osteoporosis and for the clinical testing of anti-resorptive drugs. However, osteoporotic fracture models designed to investigate novel ways to treat fractures of osteoporotic bone must fulfil requirements distinct from those of pharmacological testing.
A Hamish, Simpson, Iain R, Murray
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Animal models are widely used to investigate the pathogenesis of osteoporosis and for the clinical testing of anti-resorptive drugs. However, osteoporotic fracture models designed to investigate novel ways to treat fractures of osteoporotic bone must fulfil requirements distinct from those of pharmacological testing.
A Hamish, Simpson, Iain R, Murray
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The Osteoporotic Acetabular Fracture
Orthopedic Clinics of North America, 2013Fractures of the acetabulum are some of the most challenging fractures that face orthopedic surgeons. In geriatric patients, these challenges are enhanced by the complexity of fracture patterns, the poor biomechanical characteristics of osteoporotic bone, and the comorbidities present in this population.
Patrick D G, Henry +2 more
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Orthopedic Clinics of North America, 2013
Ankle fractures are one of the most common injuries in the elderly and their incidence is anticipated to increase over the next 20 years. Appropriate management of ankle fractures in this population requires an understanding of the issues unique to the elderly. Osteoporosis must be considered when counseling patients about their ankle fracture.
Joshua R, Olsen +2 more
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Ankle fractures are one of the most common injuries in the elderly and their incidence is anticipated to increase over the next 20 years. Appropriate management of ankle fractures in this population requires an understanding of the issues unique to the elderly. Osteoporosis must be considered when counseling patients about their ankle fracture.
Joshua R, Olsen +2 more
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Pharmacogenomics of Osteoporotic Fractures
2014Osteoporosis is a prevalent disease that typically reduces bone strength and predisposes to fractures. It is a multifactorial disorder resulting from the interaction of genetic and acquired factors. Candidate gene studies and, more recently, genome-wide studies have identified a number of polymorphisms significantly associated with bone mass and ...
José A, Riancho, Flor M, Pérez-Campo
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Fractures of the Osteoporotic Spine
Orthopedic Clinics of North America, 1990Prior to fracture, the osteoporotic spine can be analyzed in several ways. After fracture occurs, however, a simple plain roentgenogram usually suffices to make the diagnosis of compression fracture. If severe deformity threatens, or if there is a neurologic lesion, the surgeon now has options not previously available.
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Fracture risk following an osteoporotic fracture
Osteoporosis International, 2003The aim of this study was to examine the pattern of fracture risk following a prior fracture at the spine, shoulder or hip. We studied 1918 patients with fractures at these sites identified from the Department of Radiology in Malmo who were followed for 5 years.
Johnell, O +7 more
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Biomechanics of osteoporotic fractures
Injury, 2007The objective of this review article is to present biomechanics concepts and data relevant to osteoporotic fractures. Fractures are mechanical events that occur when the applied load exceeds the fracture load (bone strength); both loading and strength must be considered to understand fracture risk.
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