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Pharmacogenomics of Osteoporotic Fractures
2014Osteoporosis is a prevalent disease that typically reduces bone strength and predisposes to fractures. It is a multifactorial disorder resulting from the interaction of genetic and acquired factors. Candidate gene studies and, more recently, genome-wide studies have identified a number of polymorphisms significantly associated with bone mass and ...
José A, Riancho, Flor M, Pérez-Campo
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Fractures of the Osteoporotic Spine
Orthopedic Clinics of North America, 1990Prior to fracture, the osteoporotic spine can be analyzed in several ways. After fracture occurs, however, a simple plain roentgenogram usually suffices to make the diagnosis of compression fracture. If severe deformity threatens, or if there is a neurologic lesion, the surgeon now has options not previously available.
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Biomechanics of osteoporotic fractures
Injury, 2007The objective of this review article is to present biomechanics concepts and data relevant to osteoporotic fractures. Fractures are mechanical events that occur when the applied load exceeds the fracture load (bone strength); both loading and strength must be considered to understand fracture risk.
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[The epidemiology of osteoporotic fractures].
Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna, 1995Fractures represent the most important consequence of osteoporosis, as well as the major determinant of the socio-economic costs of the disease. Distal forearm, vertebrae and proximal femur fractures are frequently associated with the disease. Colles' fractures generally occur in women, showing a progressive increase in incidence after the onset of ...
SARTORI, LEONARDO, MAGGI S.
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Treatment of Osteoporotic Fractures
Scandinavian Journal of Surgery, 2002Fractures are the most common problem associated with osteoporosis and despite advances in prevention and treatment of osteoporosis the number of fractures continue to increase. Along with the three classic locations hip, spine and wrist, there are several other fractures that commonly are related to osteoporosis.
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Neurosurgery, 1988
Traumatic sacral fractures are most often due to motor vehicle or industrial accidents and are commonly associated with pelvic, urogenital, and neurological injuries. In recent years, a more subtle type of sacral fracture, not associated with major trauma, has been described.
C E, Rawlings +3 more
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Traumatic sacral fractures are most often due to motor vehicle or industrial accidents and are commonly associated with pelvic, urogenital, and neurological injuries. In recent years, a more subtle type of sacral fracture, not associated with major trauma, has been described.
C E, Rawlings +3 more
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Mortality after osteoporotic fractures
Osteoporosis International, 2003The aim of this study was to examine the pattern of mortality following osteoporotic fractures at the spine, shoulder, hip, and forearm. We studied 2,847 patients with fractures at these sites identified from the radiology department in Malmö, Sweden.
Johnell, O +7 more
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Principles of osteoporotic fracture treatment
Best Practice & Research Clinical Rheumatology, 2013The number of osteoporotic fractures is still increasing and the overall management of these multimorbid patients is demanding. Surgical management of these fractures is challenging due to often comminuted fractures and poor purchase of implants.
C, Kammerlander +4 more
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RISK FACTORS FOR OSTEOPOROTIC FRACTURE
Endocrinology and Metabolism Clinics of North America, 1998Fracture prevention requires the identification of individuals at risk prior to fracture. Bone density, a history of previous fractures, biochemical markers, and the frequency and types of falls are important risk factors for fractures. There are also many other risk factors for bone loss, falls, and fractures.
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Efficacy of treatment of osteoporotic fractures
The American Journal of Medicine, 1995The efficacy of osteoporosis therapy can be considered at several different levels, ranging from the overall community to the individual patient. Efficacy has different connotations for each group within the community and for the individual, in whom life expectancy--among other parameters--is an important consideration.
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