Results 51 to 60 of about 1,382 (169)

UHPLC–MS based metabolomics study of the ErZhi formula on skeletal muscle against osteosarcopenia focusing on energy metabolism

Animal Models and Experimental Medicine, Volume 9, Issue 6, Page 1235-1247, June 2026.
ErZhi formula (EZF) is composed of Ligustri Lucidi Fructus (LLF) and Ecliptae herba (EH). Ovariectomized (OVX) and sham rats received 12‐week intragastric treatment with EZF, alendronate, and vehicle saline. Gastrocnemius tissues were harvested to systematically evaluate pharmacodynamic changes in skeletal muscle morphology, mitochondrial ...
Yuqing Pang, Ningning Li, Yujie Ding, Shuzhen Hou, Jing Liu, Xiuxue Liu, Erwei Liu, Xiaopeng Chen   +7 more
wiley   +1 more source

Vitamin D and osteosarcopenia [PDF]

Current Opinion in Clinical Nutrition & Metabolic Care, 2017
The review summarizes recent epidemiological studies that examined the relationship between osteoporosis and sarcopenia to assess the impact of vitamin D status or supplementation on health outcomes related to these two medical conditions.Osteoporosis and sarcopenia are major public health problems, but whether these two diseases should be considered ...
Bruyère, Olivier, CAVALIER, Etienne, Reginster, Jean-Yves   +2 more
openaire   +2 more sources

Prognostic significance of osteosarcopenia and its effects on immune response in patients with stage II/III gastric cancer

Cancer Immunology, Immunotherapy
Background Osteosarcopenia, characterized by muscle loss and osteoporosis, has emerged as a prognostic marker for various malignancies. However, its impact on the immune response in gastric cancer remains unclear.
Yuki Hirase, Takaaki Arigami, Daisuke Matsushita, Masataka Shimonosono, Yusuke Tsuruda, Ken Sasaki, Kenji Baba, Yota Kawasaki, Takao Ohtsuka   +8 more
doaj   +1 more source

Association of osteosarcopenia with physical frailty and cachexia in patients undergoing hemodialysis: the REPnet-HD study

Renal Replacement Therapy
Aim The association between osteosarcopenia and the development of physical frailty (PF) or cachexia in patients undergoing hemodialysis (HD) remains unclear.
Masakazu Saitoh, Naoto Usui, Sho Kojima, Yoichi Sato, Yoshifumi Abe, Akihiro Sakuyama   +5 more
doaj   +1 more source

Disability, Frailty and Depression in the community-dwelling older adults with Osteosarcopenia

BMC Geriatrics, 2021
Background The purpose of this study was to investigate the prevalence of osteosarcopenia in the over 60-year-old community and to evaluate whether osteosarcopenia is associated with disability, frailty and depression.
Ki-Soo Park, Gyeong-Ye Lee, Young-Mi Seo, Sung-Hyo Seo, Jun-Il Yoo   +4 more
doaj   +1 more source

From Pixels to Prediction: Reviewing the Role of Artificial Intelligence in Body Composition Analysis

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Evaluation of body composition (BC) is a set of biomarkers, including fat, muscle and bone, that allows the quantification of an individual's composition at different levels of complexity (whole body, tissues, macroscopic and microscopic). Recently, BC has gained medical interest due to its impact on health outcomes in both oncologic and non ...
Marta Zerunian, Benedetta Masci, Stefano Nardacci, Federico Perconti, Lapo Nardoni, Vincenzo Solimene, Michela Polici, Francesco Pucciarelli, Tiziano Polidori, Domenico De Santis, Andrea Laghi, Damiano Caruso   +11 more
wiley   +1 more source

Low geriatric nutritional risk index is associated with osteosarcopenia in older patients with type 2 diabetes mellitus

BMC Musculoskeletal Disorders
Background The association between the geriatric nutritional risk index (GNRI) and osteosarcopenia in older adults with type 2 diabetes mellitus (T2DM) is not clear. Methods A total of 573 individuals with T2DM were included in this cross-sectional study.
Xiaoye Duan, Jagadish K. Chhetri, Lina Sun, Zhijing Mu, Junling Fu, Shuangling Xiu   +5 more
doaj   +1 more source

Aging‐Related Muscle Bmal1 Decline Contributes to Bone Loss in Mice via Enhancing IL‐1α–Mediated Osteoclastogenesis

Aging Cell, Volume 25, Issue 6, June 2026.
Aging‐related decline of muscle Bmal1 drives bone loss in mice by disrupting Hmox1 and increasing IL‐1α, which promotes osteoclast activity. Time‐restricted feeding reestablishes diurnal Hmox1 expression, reduces IL‐1α, and alleviates osteoporosis, offering a potential therapeutic strategy. ABSTRACT Osteoporosis, a common metabolic bone disorder linked
Kai Huang, Jun Qian, Yike Wang, Feng Zhang, Youjia Xu, Qiaocheng Zhai   +5 more
wiley   +1 more source

Lacto-ovo-vegetarian diet is inversely associated with the osteosarcopenia in older adults

BMC Geriatrics
Objective Osteosarcopenia adversely affects the quality of life and physical health of older adults. We sought to explore the association between dietary patterns and osteosarcopenia in community-dwelling older adults.
Runnian Huang, Junwei Hu, Yi Li, Sijia Yang, Xin Li, Tianbo Hou, Zibo Ning, Chunhua Ma, Xiaoyue Yuan, Zheng Wang, Tiantian Zhang, Difei Wang   +11 more
doaj   +1 more source

The Role of Extracellular Vesicles MicroRNAs in Sarcopenia: From Aging to Multi‐Morbidity

AGING MEDICINE, Volume 9, Issue 2, Page 185-195, April 2026.
Exosomes transporting miRNAs play a crucial bidirectional regulatory role in the process of sarcopenia, both in natural aging and under various pathological conditions. ABSTRACT Sarcopenia, defined as progressive loss of skeletal muscle mass and function, occurs during aging and has also been recognized for its detrimental effects in various disease ...
Bingyu Huang, Zhao Peng, Lin Kang
wiley   +1 more source