Results 21 to 30 of about 1,820,592 (313)

OT-82, a novel anticancer drug candidate that targets the strong dependence of hematological malignancies on NAD biosynthesis

open access: yesLeukemia, 2020
Effective treatment of some types of cancer can be achieved by modulating cell lineage-specific rather than tumor-specific targets. We conducted a systematic search for novel agents selectively toxic to cells of hematopoietic origin.
L. Korotchkina   +22 more
semanticscholar   +1 more source

Infinite-body optimal transport with Coulomb Cost [PDF]

open access: yes, 2013
We introduce and analyze symmetric infinite-body optimal transport (OT) problems with cost function of pair potential form. We show that for a natural class of such costs, the optimizer is given by the independent product measure all of whose factors are
Cotar, Codina   +2 more
core   +3 more sources

LncRNA SOX2‐OT regulates AKT/ERK and SOX2/GLI‐1 expression, hinders therapy, and worsens clinical prognosis in malignant lung diseases

open access: yesMolecular Oncology, 2020
The involvement of LncRNA SOX2‐overlapping transcript (SOX2‐OT), SOX2, and GLI‐1 transcription factors in cancer has been well documented. Nonetheless, it is still unknown whether co‐expressed SOX2‐OT/SOX2 or SOX2‐OT/SOX2/GLI‐1 axes are epigenetically ...
A. Herrera-Solorio   +12 more
semanticscholar   +1 more source

HST Observations of the Host Galaxy of GRB970508 [PDF]

open access: yes, 1999
We report on observations of the field of GRB~970508 made in early August 1998, 454 days after outburst, with the STIS CCD camera onboard the Hubble Space Telescope.
A. S. Fruchter   +19 more
core   +2 more sources

Finding Phenotypic Biomarkers for Drought Tolerance in Solanum tuberosum

open access: yesAgronomy, 2023
Climate change models predict increased drought frequencies. Maintaining yield stability necessitates drought-tolerant crops. However, their breeding is challenging; drought tolerance is a multigene trait with significant environment interaction.
Karin I. Köhl   +2 more
doaj   +1 more source

Central oxytocin and food intake: focus on macronutrient-driven reward [PDF]

open access: yes, 2015
Centrally acting oxytocin (OT) is known to terminate food consumption in response to excessive stomach distension, increase in salt loading, and presence of toxins.
Klockars, Anica   +2 more
core   +3 more sources

A transaminase with β-activity from Variovorax boronicumulans for the production of enantiopure β-amino acids

open access: yesHeliyon, 2023
Enantioselective transamination of amino acids is a great challenge in biotechnology as suitable enzymes with wide substrate spectrum are rare. Here, we present a new transaminase from Variovorax boronicumulans (VboTA, Variovorax boronicumulans ω ...
Uwe Wegner   +6 more
doaj   +1 more source

Functional Outcomes of the Low Vision Depression Prevention Trial in Age-Related Macular Degeneration. [PDF]

open access: yes, 2017
Purpose: To compare the efficacy of behavioral activation (BA) plus low vision rehabilitation with an occupational therapist (OT-LVR) with supportive therapy (ST) on visual function in patients with age-related macular degeneration (AMD). Methods: Single-
Casten, Robin J.   +4 more
core   +3 more sources

Efficient Two-Round OT Extension and Silent Non-Interactive Secure Computation

open access: yesIACR Cryptology ePrint Archive, 2019
We consider the problem of securely generating useful instances of two-party correlations, such as many independent copies of a random oblivious transfer (OT) correlation, using a small amount of communication.
Elette Boyle   +6 more
semanticscholar   +1 more source

Long Noncoding RNA SOX2-OT: Regulations, Functions, and Roles on Mental Illnesses, Cancers, and Diabetic Complications

open access: yesBioMed Research International, 2020
SRY-box transcription factor 2 (SOX2) overlapping transcript (SOX2-OT) is an evolutionarily conserved long noncoding RNA. Its intronic region contains the SOX2 gene, the major regulator of the pluripotency of embryonic stem cells.
Pu-yu Li   +3 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy