Results 141 to 150 of about 344,896 (264)

Downregulation of EPAS1 and EGLN1 mRNA Expression Associated With High‐Altitude Adaptive Genetic Variants in Sherpa Highlanders

open access: yesAnnals of Human Genetics, Volume 90, Issue 3, Page 202-214, May 2026.
ABSTRACT Background and Aims Sherpa highlanders exhibit remarkable tolerance to hypoxia, most likely due to genetic adaptations shaped by natural selection at high altitude. This study examined the roles of endothelial PAS domain protein 1 (EPAS1) and egl‐9 family hypoxia‐inducible factor 1 (EGLN1) in the genetic mechanisms underlying this adaptation ...
Yunden Droma   +5 more
wiley   +1 more source

Clinical Outcomes and Non‐Invasive Testing in Metabolic Dysfunction‐Associated Steatohepatitis With Cirrhosis: A Systematic Review

open access: yesLiver International, Volume 46, Issue 5, May 2026.
ABSTRACT Background and Aims Metabolic dysfunction‐associated steatohepatitis (MASH) with cirrhosis lacks definitive treatments and poses an increasing healthcare burden globally. We undertook a systematic literature review (SLR) to better understand the disease burden in cirrhosis due to MASH.
Hannes Hagström   +8 more
wiley   +1 more source

Persistent Decline of the Piscivorous Cyprinid, Opsariichthys uncirostris, in Lake Biwa Despite Recovery Trends Among Other Native Species

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 2, April 2026.
Three‐lips is the sole piscivorous cyprinid in Japan, which pursues lures aggressively. This study surveyed the persistent decline of the species over thirteen years. This is a mature male individual caught in 2016. ABSTRACT Freshwater ecosystems are increasingly recognised as highly susceptible to anthropogenic disturbances.
Akio Imamura, Atsushi Maruyama
wiley   +1 more source

Underwater Endoscopic Mucosal Resection as a Salvage Strategy for a Non‐Lifting Early Sigmoid Colon Carcinoma After Failed Conventional Endoscopic Mucosal Resection: A Case Report

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Endoscopic mucosal resection (EMR) has been widely adopted as an endoscopic treatment for colorectal tumors. However, in non‐lifting lesions, EMR often becomes technically challenging, leading to piecemeal resection or residual tumor. Recently, underwater EMR (UEMR) has been developed as a novel technique that allows mucosal and submucosal ...
Hiroshi Sawaguchi   +4 more
wiley   +1 more source

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