Results 131 to 140 of about 37,423 (189)

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Molecular Pathology of Advanced NSCLC: Biomarkers and Therapeutic Decisions. [PDF]

Cancers (Basel)
Winter M, Jeroch J, Wetz M, Rauschendorf MA, Wild PJ.   +4 more
europepmc   +1 more source

Chinese pan‐cancer patient genomic characteristics: A comprehensive analysis based on the National Cancer Center–Clinical Diagnostics Knowledgebase real‐world clinical sequencing cohort

Interdisciplinary Medicine, EarlyView.
We assembled National Cancer Center–Clinical Diagnostics Knowledgebase, a clinical genomic knowledgebase of 6935 tumors with matched normal samples, revealing key somatic alterations and actionable variants (70.2% of the cohort). Enrichment of certain different gene mutations was observed between Chinese and American populations, along with a strong ...
Hongrui Li, Shun Wang, Guowei Zhao, Jiangtao Li, Xin Li, Bingning Wang, Yi Zhang, Mengfei Yao, Lei Guo, Jianming Ying, Wenbin Li   +10 more
wiley   +1 more source

Impact of obesity on follicular fluid lipid composition and IVF/ICSI outcomes in Korean women: A lipidomic study. [PDF]

PLoS One
Ko YR, Kim MK, Kim JW, Han EJ, Kim SJ, Park JK, Ahn SY, Lee M, Oh S, Hwang S, Kim D, Lim HJ, Lee WS.   +12 more
europepmc   +1 more source

Holistic bone developing microenvironment engineered apoptotic extracellular vesicles recapitulate multidimensional developmental signatures in adult and senile bone repair

Interdisciplinary Medicine, EarlyView.
The developing bone was identified as an M2a‐like macrophage driven immune microenvironment with multidimensional developmental signatures. hME‐ApoEVs were successfully fabricated via stimulating the M2a‐like developing microenvironment in vitro and confirmed its recapitulation of developmental features.
Xiaoran Yu, Jieyun Xu, Yuan Zhao, Xinyu Guo, Hongcheng Chen, Junlong Xue, Yong Ao, Linjun Zhang, Xiaomeng Gao, Xueli Mao, Songtao Shi, Zetao Chen   +11 more
wiley   +1 more source

Kendrick Mass Defect Filtering Enables High-Throughput Untargeted Annotation of Minor Phytocannabinoids: Toward Streamlined Phytocannabinomics. [PDF]

ACS Meas Sci Au
Cerrato A, Cannazza G, Citti C, Laganà A, Paris R, Capriotti AL.   +5 more
europepmc   +1 more source

Placenta‐derived extracellular vesicles: Signal messengers shuttling across the maternal‐fetal barrier

Interdisciplinary Medicine, EarlyView.
In normal pregnancy, PEVs help maintain maternal–fetal immune tolerance while enabling controlled immune activation, promote endothelial migration, and support trophoblast invasion and syncytialization, strengthening antimicrobial defense. In pregnancy‐related disorders, dysregulated PEV signaling may drive endothelial dysfunction and hypertension, BBB
Jiale Du, Maliang Tao, Yanxuan Xiao, Zhijian Wang, Bo Situ, Lei Zheng   +5 more
wiley   +1 more source

Prebiotics and Gut Health: Mechanisms, Clinical Evidence, and Future Directions. [PDF]

Nutrients
Monteiro CRAV, Bogea EG, Campos CDL, Pereira-Filho JL, Almeida VSS, Vale AAM, Azevedo-Santos APS, Monteiro-Neto V.   +7 more
europepmc   +1 more source

The prevalence of food insecurity and its relationship with wellbeing in a large, cross‐sectional study of children and young people in England

JCPP Advances, EarlyView.
AbstractBackgroundWe aimed to assess the prevalence of food insecurity reported by children and young people in four areas of England in 2023 and examine its association with mental health and wellbeing.MethodsWe used data from the OxWell student survey, a large, diverse, cross‐sectional study of 38,430 students aged 8–19 years, conducted primarily in ...
Giacomo Bignardi, Mina Fazel, OxWell Study Team, Sarah‐Jayne Blakemore   +3 more
wiley   +1 more source

Lipid metabolism disorders and osteoarthritis: New evidence from multiple studies. [PDF]

Medicine (Baltimore)
Li Z, Du B, Su Y, Cui Y, Ren T, Yang Y, Ji S, Li Z.   +7 more
europepmc   +1 more source