Results 131 to 140 of about 587,980 (268)

Distinguishing and connecting self and others

, 2013
Als je de film "I am legend" hebt gezien, met Will Smith in de hoofdrol, heb je misschien hevige gevoelens van wanhoop en eenzaamheid ervaren. Omdat we geboren zijn als sociale dieren, is het om te overleven uiterst belangrijk om jezelf zowel te kunnen onderscheiden van, als te verbinden met anderen.
openaire   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Using Collaborative Model Building to Better Understand the Mechanisms of Alcohol-Involved Sexual Violence on College Campuses: Post Hoc Protocol. [PDF]

JMIR Res Protoc
Dougherty M, Burke JG, Alejandro J, Moore TR, Coulter RWS, Futcher R, Miller E, Mair C.   +7 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Rethinking social capital in wildfire resilience: the case of central Portugal. [PDF]

Disasters
Fachada C, Mendes JM.
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

The role of professional networks and institutional prestige in shaping the first career moves of scholars. [PDF]

PNAS Nexus
Rottenkolber A, Ali O, Mónus G, Li J, Kim J, Perrotta D, Akbaritabar A.   +6 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Predicting individual differences of fear and cognitive learning and extinction. [PDF]

Nat Commun
Gomes CA, Bach DR, Razi A, Batsikadze G, Elsenbruch S, Engler H, Ernst TM, Fellner MC, Fraenz C, Genç E, Klass A, Labrenz F, Lissek S, Merz CJ, Metzen D, Nostadt A, Pawlik RJ, Schneider JE, Tegenthoff M, Thieme A, Wolf OT, Güntürkün O, Quick HH, Kumsta R, Timmann D, Spisak T, Axmacher N.   +26 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source