Results 191 to 200 of about 21,635,005 (257)

Functional connectivity is linked to symbolic BOLD patterns: Replication, extension, and clinical application of the human "Complexome". [PDF]

Netw Neurosci
Romanello A, von Schwanenflug N, Franka M, Paul F, Prüss H, Krohn S, Finke C.   +6 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Adaptive Residual Correction Network for Efficient Single Image Super-Resolution. [PDF]

Sensors (Basel)
Tian J, Guo J, Feng B, Zhu H, Luo Y.
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Direct Molding of Luer Connections in PDMS Microfluidic Devices: Comparison with Conventional Interface Methods. [PDF]

Micromachines (Basel)
Layedra G, Vallejo Janeta AP, Gimenez R, Isa Jara R, Peñaherrera-Pazmiño AB, Mayorga-Ramos A, Rosero G, Perez MS, Lerner B.   +8 more
europepmc   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Experiments on Nonlocal Fluid-Flow Metamaterials. [PDF]

Adv Sci (Weinh)
Wang K, Chen Y, Wegener M.
europepmc   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Brain network topology and neural mechanisms in Sanda athletes: a comparative study across training levels. [PDF]

Front Neurosci
Chen Y, Jia Z, Zhao Z, Zhou J, Lin Y, Zhao B.   +5 more
europepmc   +1 more source

Walking the talk for dementia: building social networks and collaborations. [PDF]

Implement Sci Commun
Dawson WD, Reed J, Aguzzoli-Peres F, Irving K, Gelmon SB.   +4 more
europepmc   +1 more source