Results 171 to 180 of about 31,235,632 (381)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Impact of EU Education Programmes on Challenging “Otherness”: Turkish Case

open access: diamond, 2013
Mehmet Nurettin Alabay   +1 more
openalex   +1 more source

EMPLOYMENT, GENDER, EDUCATION AND OTHER RELEVANT VARIABLES: THE FINANCIAL CRISIS IMPACT IN SPAIN [PDF]

open access: yes
The present paper aims to ascertain whether gender differences continue to exist in Spain’s working population. It sets out to obtain empirical evidence of the employment profile according to gender, quantify the extent to which self-employment or ...
Flora M. Diaz-Perez   +1 more
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

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